巻号一覧
9 巻, 1 号
選択された号の論文の14件中1～14を表示しています
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原稿種別: 表紙
1960 年 9 巻 1 号 p. Cover1-
発行日: 1960/01/01
公開日: 2016/10/20
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原稿種別: 表紙
1960 年 9 巻 1 号 p. Cover2-
発行日: 1960/01/01
公開日: 2016/10/20
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国頭 昌一原稿種別: 本文
1960 年 9 巻 1 号 p. 1-15,93
発行日: 1960/01/01
公開日: 2016/10/20
ジャーナル フリーGuinea pigs were passively sensitized with anti-horse rabbit serum and shocked with horse serum. General anesthesia with ether and the injections of Chlorpromazine, Buscopan, Hexamethonium bromide or Predonin were performed before the shocking injection in order to investigate the protective effect against the death by anaphylactic shock. The protective effect of the artificial respiration and the injection of d-Tubocurarine chloride against anaphylaxis was also tested. From the results obtained it might be concluded that the combination of antigen and antibody might be carried out regardless of blocking the autonomous nervous system, and the death due to anaphylactic shock might be mainly caused by the whole body spasms, particularly by the spasms of the thoracic muscle. It the spasms were inhibited, the animals were removed from asphyxia and the animals life were prolonged but died before long. Considering from the reduction of carbon dioxide, the fall of pH and the increase of amino acid nitrogen in the arterial blood, secondary shock will lead animals to death and if the animals were protected from the secondary shock the animals may be protected from the death. Therefore the removal of the acute asphyxia may be the most effective protecting method against the death by anaphylactic shock.抄録全体を表示PDF形式でダウンロード (2055K) -
林 豊田原稿種別: 本文
1960 年 9 巻 1 号 p. 16-29,93-94
発行日: 1960/01/01
公開日: 2016/10/20
ジャーナル フリーExperimental Studies were carried out on the prolonging or the relief of life in anaphylactic shock, which is a typical pattern of the acute death. The author studied the process of it from the viewpoint of electrocardiogram, respiratory curve, blood pressure, and the pathohistological findings, but not a change was observed in the guinea pig relieved from the death. Kunito, a colaborator of the author, found that the course of the death in anaphylactic shock was acute asphyxia and succeeded in prolonging life of the animals by means of the mechanical and pharmacological method, but could not protect them completely and resulted them the delayed type of the death. The present author pointed out that the latter was due to the development of the secondary shock from the findings on the change of arterial blood gases, and established a method of the complete protection against the secondary shock. Similar curves of the blood pressure were obtained in the cases of the death due to anaphylactic shock and the acute asphyxia and the delayed type of death due to the chronic asphyxia. As to the respiration more prolonged inspiratory dyspnoea was observed than in the case of the acute asphyxia, and the characteristic rectangular waves were recognized in the delayed type of the death. It may be a course of dyspnoea, together with the contraction of the bronchi and atelectasis of the lung demonstrated histilogically and will play an important role in the development of the secondary shock, as in the case of the chronic asphyxia due to the forced respiration. In addition, the organs manifested the paren-cymatous changes as described in the literatures of the secondary shock in the case of the delayed type of death. On the other hand, in the case of death due to anaphylactic shock rupture of cardiac muscle was observed in the heart. This was a characteristic finding and it was also observed in the electrocardiogram myocardial injury appeared from the earlier stage. Not a common finding was observed between the death due to anaphylactic shock and the various types of shock.抄録全体を表示PDF形式でダウンロード (3828K) -
池上 春雄原稿種別: 本文
1960 年 9 巻 1 号 p. 30-41,94
発行日: 1960/01/01
公開日: 2016/10/20
ジャーナル フリーIn 1951 Okabayashi demonstrated in the sensitized rabbit a characteristic focal lesion induced by the repeated subcutaneous injections of antigen at the same site of the back. It was later designated as "prolonged Arthus phenomenon" by him. The author studied on the prolonged Arthus phenomenon which had been brought our in the sensitized rabbit following the repeated subcutaneous injections of egg whit at the same site of the auricule. In twenty-fifth day of the experiment there occurred so-called allergic demarcating inflammation; that is a prolonged granulating inflammation characterized by formation of a layer of the fibrinoid necrosis. More-over, it was histologically shown that the allergic demarcating inflammation was subject to an antiphlogistic or prophlogistic influence following the administration of cortisone or DOCA respectively. The administration of cortisone resulted the development of a markedly weakened demarcating inflammation, while that of DOCA was followed by a severe demarcation with the deeper demarcating inflammation.抄録全体を表示PDF形式でダウンロード (2759K) -
児島 成男原稿種別: 本文
1960 年 9 巻 1 号 p. 42-59,94-95
発行日: 1960/01/01
公開日: 2016/10/20
ジャーナル フリーThe change of the enzymatic system of the guinea pig by anaphylaxis, Forssman shock, histamine or acetylcholine shock and the injection of the bacterial exotoxin (diphtheria, tetanus) were investigated histochemically. As the enzyme in the tissues alkali and acid phosphatase (Kolle method), succinate dehydrogenase (Wechstein et Meisel method) and amine oxydase (reduction method with kallium tellurite acid by Takamatsu) were studied. By these histochemical methods the activities and localizations of the enzymes in the normal and shocked guinea pigs were clarified. From the results of the experiments the change of the enzyme by various shocks depend upon the kinds of the enzyme, the tissue and the localization of the cells. Comparing to the control group, the enzymatic activity after the shocks was observed to be increased in some cases, but in other cases it was observed to be decreased. The most remarkable change of alkali and acid phosphatase, lipase, cholinesterase, succinate dehydrogenase and amine oxydase were observed in anaphylaxis, next in Forssman shock and then in the case of the guinea pig injected the bacterial toxin. Not a remarkable change was observed in cholinesterase in histamine and acetylcholine shocks.抄録全体を表示PDF形式でダウンロード (3009K) -
真木 実原稿種別: 本文
1960 年 9 巻 1 号 p. 60-74,95
発行日: 1960/01/01
公開日: 2016/10/20
ジャーナル フリーProf. S. Matsukura and co-workers have ever demonstrated that the infection by E. Coli might have a significant role in the mechanism of producing cholecystitis. The author studied serologically on the patients suffering from cholecystitis and considered that there exists allergy by the components of E. Coli in cholecystitis. So the author studied experimentally on the relation between the infection of E. Coli and the cholecystitis by allergic and Schwartzman type reaction in the dog. Cholecystitis could not be recognized in the normal dog, even if a great number of living E. Coli were injected into the gall-blader. However, the dog sensitized with horse serum or treated with the filtrate of E. Coli produced the allergic or Schwartzman type cholecystitis, when the horse serum or the filtrate of E. Coli were reinjected. Moreover the cholecystitis produced by the injection together with E. Coli into the gall-bladder were more remarkable. These facts were clearly demonstrated by the autopsy and the patho-histological changes. From the results obtained above mentioned it might be concluded that the infection by E. Coli may strengthen the producing mechanism of cholecystitis by allergic or Schwartzman reactin. Above all, the calculi were observed in the gall-bladder cases. These finding may give a important suggestion to the theory on the forming of the calculi and the mechanism of the cholecystitis.抄録全体を表示PDF形式でダウンロード (2945K) -
梶谷 恵佑原稿種別: 本文
1960 年 9 巻 1 号 p. 75-92,95-96
発行日: 1960/01/01
公開日: 2016/10/20
ジャーナル フリーRabbits were mainly used in the experiments on vagal action current in anaphylaxis. By perfusing 5-HT or ATP into the left ventricle of the rabbit, the fall of blood-pressure bradycardia alteration were produced as same as in anaphylaxis and at the same time the increase of the amplitude and frequency of the spikes in the vagal action current were recognized. On the other hand, a remarkable increase of 5-HT and ATP was observed in the left ventricle of the rabbit in anaphylaxis. By the transecting method of the vagal branches it was clarified that the cardiac branch of the left vagus might have the major role in the development of anaphylaxis. The remarkable change of the vagal action current was observed in anaphylaxis; the intensity of it was of it over 100-200μv and and its transmission rate was 3-15 m/sec; moreover, when such a remarkable electric change was observed, shock response always developed. When the receptors of the vagus nerve were blocked, no change was observed in the vagal action current, even if anaphylaxis were developed. Anaphylactic shock did not develop when the prechiasmatic area and sympathetic zone c were destroyed and not a change of the vagal action current was observed in such a case. Destruction of the posterior hypothalamus and sympathetic zone b could not prevent the development of anaphylaxis and also the remarkable change was observed in the vagal action current. The sympathetic nerve may not play an important role in the development of anaphylaxis, nor effect any change to its action current. In conclusion, anaphylaxis may be developed as the responses through the cardiac branch of the left vagus nerve by such activators as 5-HT or ATP.抄録全体を表示PDF形式でダウンロード (3268K) -
原稿種別: 文献目録等
1960 年 9 巻 1 号 p. 93-96
発行日: 1960/01/01
公開日: 2016/10/20
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原稿種別: 付録等
1960 年 9 巻 1 号 p. 97-
発行日: 1960/01/01
公開日: 2016/10/20
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原稿種別: 文献目録等
1960 年 9 巻 1 号 p. 98-
発行日: 1960/01/01
公開日: 2016/10/20
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原稿種別: 付録等
1960 年 9 巻 1 号 p. App1-
発行日: 1960/01/01
公開日: 2016/10/20
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原稿種別: 表紙
1960 年 9 巻 1 号 p. Cover3-
発行日: 1960/01/01
公開日: 2016/10/20
ジャーナル フリーPDF形式でダウンロード (76K) -
原稿種別: 表紙
1960 年 9 巻 1 号 p. Cover4-
発行日: 1960/01/01
公開日: 2016/10/20
ジャーナル フリーPDF形式でダウンロード (76K)
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