アレルギー
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
9 巻, 12 号
選択された号の論文の14件中1~14を表示しています
  • 原稿種別: 表紙
    1960 年 9 巻 12 号 p. Cover5-
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
  • 原稿種別: 表紙
    1960 年 9 巻 12 号 p. Cover6-
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
  • 的場 八千代
    原稿種別: 本文
    1960 年 9 巻 12 号 p. 941-949,1004
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
    The antigenicity of the pollens of American giant and common ragweed which are regarded as the most important factor in asthma and hey feber and butakusa which grows in Japan, originating for the American ragweed botanically are compared, of 120 asthma patients who were intradermally tested with butakusa pollen extract, 15 showed a positive reaction (2: 3 plus positive, 3: 2 plus positive, 10: 1 plus positive). 10 of these positive patients were intradermally tested with a further 2 pollen extracts-American giant and common ragweed, and also were exposed to the above mentioned 3 pollen. Three cases showed wheezing after nasal inhalation of butakusa pollen, 1 case after nasal inhalation of giant ragweed, 1 case after common ragweed pollen. 8 patients were tested by the passive transfer method of Prausnitz Kuestner and 3 showed a positive result. But there was no definite correlation between the positive result and clinical symptom. Sera of intradermal test positive and negative patients were tested for hemagglutinability of tannic acid and protein treated red blood cells, but hemagglutination did not develop. The author performed antigen-antibody studies with the precipitation ring test, Ouchterlony test and hemagglutination test, using tannic acid and protein treated red blood cells, and found that giant, common and butakusa pollen are serologically different and butakusa pollen is far different form giant ragweed pollen and even different from common ragweed pollen, too.
  • 金子 康男, 進藤 宙二, 芳賀 邦夫, 根津 尚光, 樋渡 喜一, 高倉 熈景, 羽生 順一
    原稿種別: 本文
    1960 年 9 巻 12 号 p. 950-967,1004-1
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
    Scattered data in the previous reports concerning the correlation among humoral antibodies, tuberculin skin reaction and the BCG administration on primary school children are brought together and discussed. From the readjusted results were drawn the followings. 1) The level of tuberculous humoral antibodies, in general, is elevated after the BCG administration, and maintained its level for more than three months. After one year, almost all of the cases are proved to be negative of humoral antibodies inspite of positive tuberculin skin reaction. 2) Difference in pattern of tuberculous infection between urban and rural lives which can not be defined by only the tuberculin skin test, can be seen by referring to humoral antibodies. 3) The levels of humoral antibodies in cases suffered from the BCG ulceration as well as in the naturally infected cases, in general, are high and maintained for long duration. Thus, the case with high level of humoral antibodies, even when they are proved to be negative reactors in the tuberculin skin test, might be excluded from the indication of the BCG administration. 4) It is considered that repeated tuberculin skin test as well as the BCG administration might cause the so-called early or late turn out of positive skin reaction. 5) At the stage, shortly after the BCG administration or natural infection, positivity of the tuberculin skin reaction tested with such high diluted tuberculin solution as 1:10,000 is proved to be specifically high. Further, the BCG ulceration is observed very often in cases who were proved to be positive in the tuberculin skin test with such high diluted tuberculin solution. Thus the authors are of the opinion that both of the detection of humoral antibodies and the tuberculin skin test with high diluted tuberculin solution may be effective for the early diagnosis and prevention of the BCG ulceration.
  • 宮本 昭正
    原稿種別: 本文
    1960 年 9 巻 12 号 p. 968-974,1005
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
    The skin test (scratch and intracutaneous), the eye test and the provocative test by inhalation of antigens were studied and the results were compared in 72 incidences in 31 extrinsic asthmatic patients at National Jewish Hospital (Denver, Colorado). As far as the objective tests were concerned, the provocative test with inhalation of antigens seemed to be the most accurate and logical approach to detect the causal agents of bronchial asthma. The relationship between the inhalation test and the eye test (γ=-0.64) was fairly close but there was a significant number of incidences (11 totally) in which the inhalation tests were positive but the eye tests were negative, giving the conclusion that, in the cases of bronchial asthma, one can not entirely upon the outcome of the eye test for the detection of causal agents, even though the eye tests were much more reliable than skin tests. Delayed reaction by the inhalation of causal agents was observed in 4 incidences among 35 positive result. The provocative test can be used to determine the progress of effective hyposensitization and to predict the prognosis of the patient.
  • 舘野 幸司
    原稿種別: 本文
    1960 年 9 巻 12 号 p. 975-982,1005-1
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
    Antigenicity of a mouse brain substance in Japanese B encephalitis vaccine against experimental animals, was detected by complement fixation test and collodion particle method. The circulating antibodies against the mouse brain substance were bound in the rabbits injected the vaccine, and that the antibodies reacted not only to mouse brain, but also to rabbit and human brain. It was also found histologically that the inflammatory changes might be due to brain allergy. The above results are considered to indicate that the mouse brain substance in vaccine may have the antigenicity against rabbits.
  • 舘野 幸司
    原稿種別: 本文
    1960 年 9 巻 12 号 p. 983-985,1006
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
    In the first vaccination performed by the routine method in 56 cases of schoolboys and schoolgirls, antigenicity against normal childrens of Japanese Bencephalitis vaccine were detected by complement fixation test and collodion particle method. These was no one who developed systemical or neurological manifestations after vaccination. In about 40% of all the investigated childrens antibody-titer against mouse brain and human brain in sera 3 weeks after vaccination, was elevated over the antibody-titer in pre-vaccination sera. The above results are considered to indicate that the mouse brain substance in vaccine may have the antigenicity against normal children.
  • 新井 義夫, 鈴木 広造, 高橋 昌己
    原稿種別: 本文
    1960 年 9 巻 12 号 p. 986-991,1006
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
    For the purpose of investigating the change of histamine and serotonin contents in the cells in producing anaphylactic shock, mast cells and leucocytes were isolated from the peritoneal fluid of the rat by Glick's technique (1956). This technique was almost satisfactory for isolating mast cells and leucocytes. Female albino rats, weighing 150 gms, pretreated with H. pertussis vaccine were passively sensitized with anti-egg-albumin rabbit serum (antibody-titer X64) and shocked with 2% egg-albumin 24 hours after the sensitization. Histamine was extracted by Dweutsch's method and determined biologically; Serotonin was extracted and determined by Udenfriend and Weissbach's method. The results obtained were as follows; 1) Histamine and serotonin contents in peritoneal fluid were decreased after anaphylaxis. It was also demonstrated that histamine contents in mast cells remarkably decreased and serotonin decreased slightly. 2) In leucocytes histamine also decreased clearly, however, not a change of serotonin content of it was observed after anaphylaxis.
  • 村井 ウタ
    原稿種別: 本文
    1960 年 9 巻 12 号 p. 992-1003,1007
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
    The immunological roles of leukocyte in the clinical allergy, especially bacterial one, were investigated, using the skin reaction as an index which followed the intracutaneous injection of leukocytes. Granulocytes and lymphocytes were seperated from the peripheral blood sample chiefly by means of sedimentation and centrifugation. The leukocytes thus obtained were crushed with the sonic vibration and injected intracutaneously. The leukocytes obtained from patients with various focal infections were injected to patients with various diseases and to normal subjects. Positive skin reactions were observed in patients with rheumatic endocarditis, rheumatic valvular diseases, rheumatoid arthritis, chronic glomerulonephritis, neurocirculatory asthenia, "abdominal neurosis", lupus erythematodes, food allergy, aplastic anemia, and pulmonary tuberculosis. In most of these diseases it appears that there exist allergic reactions caused by the hemolytic streptococcal infections and this probably played an important role in their pathogenesis. Positive skin reactions were generally observed more frequently in cases of lymphocyte injection than in cases of granulocyte injection. It is suggested that leukocytes, especially lymphocytes, have property to combine themselves with the bacteria (chiefly hemolytic streptococci) or antigenic bacterial substances and serve for the transportation of the latter.
  • 原稿種別: 文献目録等
    1960 年 9 巻 12 号 p. 1004-1007
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
  • 原稿種別: 索引
    1960 年 9 巻 12 号 p. 1008-1011
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
  • 原稿種別: 付録等
    1960 年 9 巻 12 号 p. App3-
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
  • 原稿種別: 表紙
    1960 年 9 巻 12 号 p. Cover7-
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
  • 原稿種別: 表紙
    1960 年 9 巻 12 号 p. Cover8-
    発行日: 1960/12/01
    公開日: 2016/10/20
    ジャーナル フリー
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