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Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
11 巻, 9-10 号
(9・10)
選択された号の論文の23件中1~23を表示しています
  • 原稿種別: 目次
    1962 年 11 巻 9-10 号 p. 419-420
    発行日: 1962/10/30
    公開日: 2017/02/10
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  • 吉利 和, 鈴木 秀郎
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 267-279
    発行日: 1962/10/30
    公開日: 2017/02/10
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  • 宮本 昭正, 可部 順三郎, 牧野 荘平
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 280-283,336
    発行日: 1962/10/30
    公開日: 2017/02/10
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    Inhalative provocation test is the excellent diagnostic method to detect the causative agent of bronchial asthma but the possibility of its danger due to possible pulmonary stretch reflex or anaphylactic shock has always been annoying. To investigate this aspect, acute distension of the lung was produced in 10 dogs by the way of deviced expiratory resistance. No dramatic change in electrocardiogram was observed unless hypoxia was kept long. Even if there occurred some changes such as extrasystole, wandering pace maker, bradycardia etc, it reversed quite easily when the distension of the lung was relieved. Considering our past clinical experience and this result, it was postulated that the test can be carried out quite safely unless patient has significant cardiac diseases.
  • 石崎 達, 横張 竜一, 荒木 英斉, 宮本 昭正, 広瀬 俊一, 可部 順三郎, 大塚 正紀, 牧野 荘平
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 284-289,336
    発行日: 1962/10/30
    公開日: 2017/02/10
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    According to the clinical investigation of 120 outpatients with bronchial asthma in our clinic during the period from Jan. to Dec. 1950 two types were recognized, namely nasal and bronchial type. Patient with predominant symptoms of rhinorrhoe and sneezing prior to the onset of asthma and or during asthmatic attacks, was classified under nasal type. Patient without such symptoms was classified under bronchial type. Between these two types there were some differences in clinical and laboratory findings as follows: 1. Nasal type was observed more frequently among the patients who had the onset of bronchial asthma in younger ages. 2. While the frequency of asthmatic attacks in nasal type was remarkably elevated in September, October and November, it did not change so much through a year in bronchial type. 3. Examinations regarding inhalatory allergens, namely intracutaneous, conjunctival, and inhalative tests were positive in 70.5%, 30%, and 48% respectively in nasal type, while they were 49.2%, 10.5% and 25% in bronchial type. 4. Incidence of eosinophilia in peripheral blood is more frequently in nasal type while leucocytosis is more predominant in bronchial type. 5. Accelarated erythrocyte sedimentation rate was observed more frequently in bronchial type. 6. Urinary proteins and abnormal electrocardiographic findings appeared in 6% and 21% in nasal type, while 33% and 50% in bronchial type. From these results following conclusion was drawn that the nasal type was more allergic and the bronchial type more infectious in etielogical point of view.
  • 樋口 健太郎, 松村 武正, 田中 一, 松田 健一郎, 熊谷 朗, 野口 義圀, 平井 義雄, 川上 保雄, 高橋 昭三, 石坂 公成, ...
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 290-296
    発行日: 1962/10/30
    公開日: 2017/02/10
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  • 遠城寺 宗徳, 田中 一, 岸 営美
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 297-298,337
    発行日: 1962/10/30
    公開日: 2017/02/10
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    According to the results of redness, thicknes and a wheal, when injected 0.05 cc of one thousandth house dust extract at the various parts of body surface, the most adequate method of skin test was found to be as follows, the time of judgment was 10 minutes and the part of injection was the side of flexion of forearm.
  • 遠城寺 宗徳, 田中 一, 松田 健一郎
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 299-300,337
    発行日: 1962/10/30
    公開日: 2017/02/10
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    1) At the injected part of skin with thick extract previously, the skin reaction seemed to be reduced. It seems that the consumption of local reagin was more severe than the part of skin injeted with thin extract. 2) At the injected part of desensitization, the skin reaction was found to be reduced compared with that before injection of extract. 3) The skin reaction at the sensitized part injected with the mixed inactive sera of asthmatic child with house dust extract who was desensitised, was reduced compared with the skin reaction at the same part of skin with mixed inactive sera of healthy child and asthmatic child who was not desensitized.
  • 松村 龍雄, 黒梅 恭芳, 館野 幸司, 木村 利定
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 301-303,337
    発行日: 1962/10/30
    公開日: 2017/02/10
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    Some observations were made on the extractions method of the house dust. Serum antibody were examined by the BDB-test, and the results of the specific desensitization therapy were followed in children with house dust asthma.
  • 熊谷 朗, 八倉 隆保, 七星 正久
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 304-306
    発行日: 1962/10/30
    公開日: 2017/02/10
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  • 高島 宏哉, 比下 潔, 春名 英彦
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 307-310,338
    発行日: 1962/10/30
    公開日: 2017/02/10
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    In an attempt to ascertain the difference of skin reactivity to "Allerpas" and house dust extracts between the asthmatics and the non-asthmatics and to investigate the relationship of the skin reactivity to some clinical findings in the former, the skin reaction test with these extracts was performed. The results obtained were as follows: 1. The skin reaction, being estimated 20 minutes after the intracutaneous injecton of the extracts, was considered "positive" when it showed a more than 16 mm. area of erythema or/and a wheal formation of more than 5 mm. in diameter. 2. The "Allerpas" and the house dust extracts showed positive skin reactions in 82.5% and in 78.4% of the 143 patients with bronchial asthma respectively, who had no previous "Allerpas" therapy, while in 91 healthy children only 19.8% showed the positive skin reaction to "Allerpas", and 21.0% to the house dust extracts. 3. The extracts of staphylococcus caused a positive skin reaction in the greatest number of the cases with a positive reactivity to "Allerpas", while streptococcal and pneumococcal component in the "Allerpas" solution caused a positive skin reaction not so frequently, and the extracts of E. coli and Mycobact. Tbc. showed a positive reaction in smaller number of the cases. 4. There was no relationship between the skin reactivity to "Allerpas" and the frequency of the episodes of recurrents upper respiratory infections in the past history of the patients with bronchial asthma. 6. The skin reaction test in the 60 patients with bronchial asthma showed a diminished reactivity to "Allerpas" after the "Allerpas" therapy, but there was no relationship between the result of the therapy and the intensity of the skin reactivity and it was impossible to consider the change of the reactivity as an indicator of the effects of the "Allerpas" therapy.
  • 大島 良雄, 石崎 達, 村中 正治, 宮本 昭正, 牧野 荘平
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 311-313,338-33
    発行日: 1962/10/30
    公開日: 2017/02/10
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    A rural population in Ehime Prefec. was surveyed for this purpose. The number of this population was 532 in total; antigens used were such as House dust, ragweed, pine tree, (1:1000 per each), and dirofilaria immitis (1:10,000). Volume of antigen injected was 0.05 ml or 0.02 ml in accordance with the survey scheme. Results were analysed statistically and concluded as follows. 1) Wheal trend to react more positive in number in 0.05 ml than in 0.02 ml of injected antigen, meanwhile there is no difference in erythema between 0.05 ml and 0.02 ml of injected antigen. And positive ratios of wheal and erythema were almost equal in 0.02 ml of injected antigen. 2) There is no necessity to inject antigen solution exactly so far inject equally as possible. 3) Variation of skin reaction due to the difference of the sites on flexor surface of the lower arm was small in range, but upper and ulnar sides of that was tended to react more largely in size bote of wheal and erythema. 4) Marginal point between negative and positive reaction in distribution curves both of wheal and erythema was constant unrelated with the site of injection volume oI injecting antigen or difference of antigen.
  • 荒木 英斉
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 314-315
    発行日: 1962/10/30
    公開日: 2017/02/10
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  • 広瀬 俊一, 石坂 公成
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 316-317
    発行日: 1962/10/30
    公開日: 2017/02/10
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  • 野口 義圀, 永井 隆吉, 平井 義雄
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 318-319,339
    発行日: 1962/10/30
    公開日: 2017/02/10
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    The intradermal skin tests were carried out with ten different food antigens, i.e., yellow tail, bonito, salmon, pampano, cuttlefish, lobster, crab, whole egg, beef and pork ham in groups as patients with acute or chronic urticaria (Group I), other skin patients who had acute or chronic urticaria in their past history (Group II), patients with urticaria due to physical causes (Group III), and normal persons (Group IV). The highest positive reaction was observed in the Group I, following Groups II, III and IV in descending order. However, the positive reaction of the skin test due to crab antigen had been shown in each group with extremely high rate. The study of the intradermal skin tests done in the small fishing town in Ehime Prefecture, using each 0.02 ml. of crab and lobster antignes with 1:1,000 and 1:10,000 dilutions, respectively, revealed that the wheal and erythema over 10 mm in diameter had been found only in some cases of the crab antigen with 1:1,000 dilution.
  • 三沢 敬義
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 320-323,339-34
    発行日: 1962/10/30
    公開日: 2017/02/10
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    Wir haben neuerdings mit Hilfe der Intrakutanprobe uber 100 Allergenextrakte bei den verschiedenartigsten Allergikern gepruft. Bei den Asthmatikern in Japan fallen diese Intrakutanproben oft positivaus. Die Intrakutanprobe mit nutritiven Allergenen, die nicht immer fur spezifisch gehalten wird, fallt bei Asthmatikern haufig stark positiv aus. Wir sahen bei den Asthmatikern in Japan haufig stark positive Intrakutanprobe gegen die Allergenextrakten von Buchweizenmehl, Makrele, Auster, Krebs und Hummer. In Japan bekamen wir am haufigsten eine positive Intrakutanprobe mit Allergenextrakten aus Hausstaub bei unseren in Tokio woeneden Asthmatikern, die jedoch klinisch nicht immer uberempfindlich gegen Hausstaub waren. In 80% bei mannlichnen Asthmatikern und in 69% bei weiblchen Asthmatikern in Japan zeigt die Intrakutanprobe mit Allergenextrakten aus Hausstaub einen positiven Ausfall. Bei der Halfte von ihnen wird ein Asthmaanfall nach der Einatmung von Hausstaub provoziert. Bei den nicht-allergischen Gesunden fallt die Intrakutanprobe mit Allergenextrakten aus Hausstaub auch oft positiv aus. Bei den Urticaria-Kranken fallt die Intrakutanprobe mit Allergenextrakten aus Hausstaub oft positiv aus, jedoch liegt der Prozentsatz des positiven Ausfalls mit Allergenextrakten aus Hausstaub bei den Urticariafallen viel niedriger als derjenige der Asthmatiker. Wir sahen bei unseren Urticariafallen ein haufig stark positive Intrakutanprobe gegen die Allergenextrakte von Auster, Krebs, Makrele, Lachs und Buchweizenmehl. Bei den Patienten mit allergischen Gastrointestinopathien fallen bei uns die Intrakutanproben mit Allergenextrakten von Makrele, Lachs, Krebs, Hummer, Auster und Buchweizenmehl auch relativ haufig positiv aus. Nach unserer klinischen Erfahrung treten Urticaria und allergische Gastrointestinopathie besonders nach dem Genuss von Krebs, Hummer, Auster und besonderen Seefischen, auch Makrele, Schweinefleisch, Buchweizennudeln und Yamwurzein auf. Bei den Heufieber-Kranken, die in Japan relativ selten sind, fallt die Intrakutanprobe mit Allergenextrakten aus Ambrosia (ragweed), Brassica cernua (common yellow mustard), Brennessel (nettle), Gansefuss (rough pigweed), Buchweizenmehl und Hausstaub haufig sehr stark aus. Die Ergebnisse unserer Intrakutanproben zeigen, dass bei den Allergikern in Japan die Uberempfindlichkeit gegen Buchweizenmehl auffallend haufiger ist als diejenige gegen Weizenmehl. In 50% bei mannlichen Kranken und in 70% bei weiblichen Kranken mit allergischen Gastrointestinopathien fallt die Intrakutanprobe mit Allergenextraten aus Buchweizenmehl stark positiv aus. Die intrakutanprobe mit Allergenextrakten aus Weizenmehl zeigt nur in 10% bei mannlichen Kranken und in 20% bei weiblichen Kranken mit allergischen Gastrointestinopathien einen positiven Ausfall. Ansonsten konnen wir hier in Japan relativ haufig die alimentare Kuhmilchallergie beobachten, die nach dem Genuss von Kuhmilch und zwar besonders von kalter Kuhmilch sofort allergische Gastrointestinopathie oder Urticaria hervorruft. Die Intrakutanprobe mit Kuhmilchextrakten zeigt nur in 10% bei mannlichen Kranken und in 30% bei weiblichen Kranken von gestrointestinaler Allergie einen positiven Ausfall, und in 21, 4% bei mannlichen Urticariafallen und in 23, 3% bei weiblichen Urticariafallen einen positiven Ausfall. Die allergische Reaktion gegen Erdbeeren beobachten wir in Japan ausserst selten. Bei Asthmatikern und nicht-allergischen Gesundedn fallt die Intrakutanprobe mit Allergenextrakt aus Erdbeeren negativ aus. Nur in 5, 7% bis 14, 3% der Urticaria-Kranken und in 0 bis 5% der gastrointestinalen Allergiker fallt die Intrakutanprobe gegen. Erdbeeren positiv aus. Nach unserer klinischen Erfahrung treten Asthmaanfalle, Urticaria, Gastrointestinopathie und Ekzeme relativ haufig besonders nach dem Genuss von Bambussprossen, Eiersflanzen und Spinat auf. Auf Grund unserer experimentellen Versuchen konnten wir beweisen, dass die asthmogene und urticariogene Wirkung der
  • 樋口 謙太郎, 松村 武正
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 324-325,340
    発行日: 1962/10/30
    公開日: 2017/02/10
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    The authors examined both methods comparatively for 50 cases of skin diseases, such as urticaria, eczema, dermatitis, neurodermatitis and others. Most of the patients have shown positive response by pricktest with the extracts of A_4 (eggs and milk), A_5 (vegetatives), A_6 (meats), A_8 (fishes), A_9 (shells and shellfishes) in food-extracts. Especially the arteficial urticaria resulted positive by all extracts. On the other hand it was positive in higher percentage by intracutane test with hausedust, shells and shellfishes and positive cases with hausedust related with the dusty circumstance or occupation. The relationship of pricktest with intracutane test (I.T/P.T) was found as 46%〜66%.
  • 川村 太郎, 笹川 正二, 木下 正子
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 326-327
    発行日: 1962/10/30
    公開日: 2017/02/10
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  • 高橋 昭三, 高島 盛輝, 谷江 澄子, 豊泉 忠, 川上 保雄
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 328-330,341
    発行日: 1962/10/30
    公開日: 2017/02/10
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    The sensitivity to four airborne molds (Aspergillus, Penicillium, Cladosporium and Alternaria), which were found most frequently in the Tokyo area, was investigated through skin tests. The mold allergens used were heat-extracted solutions. Fifty-nine per cent of the asthmatics and 18.7 per cent of the non-asthmatics showed positive immediate skin reactions to one or more mold extracts and there was a significant difference in both groups. Therefore, it seemed that these molds would play an important role as asthmogenic allergens. In the skin tests with six heat-killed bacterial vaccines (Streptococcus hemolyticus et viridans, Staphylococcus aureus et albus, Diplococcus pneumoniae and Neisseria), the incidence of the positive reactions to one or more bacterial vaccines in the asthmatics and nonasthmatics was 60 per cent and 25 per cent, respectively and showed an obvious difference. This suggested that bacteria would act as allergens. Positive skin reactions to tomato and lobster extracts showed high incidences in the patients with urticaria.
  • 杉田 和春
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 331-341
    発行日: 1962/10/30
    公開日: 2017/02/10
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    Some allergenic extracts produce erythema and wheal in intracutaneous testings. These reactions seem to bo induced by the entanglement of complicated determinant group of antigens and complicated reactive group of antibodies. We should perform hyposensitization therapy using the allergenic extracts which react to be the most positive and react to considerably low dilution test we should fail to treat the determinant group and reactive group causing allergic manifestations. When several kinds of allergenic extracts react mutually to the same degree by intracutaneous tests, we think they have common antigens, and so we have studied their frequency. The following are the percentages of the patients whose intradermal reaction was as strong as with House dust: 0.7% with Coryptomeria japonica, 3.3% with Poa pratehsis, 3.8% with Plantago lanceolata, 0.6% with Dactylis glomerata, 10.8% with Typha angustata, 5.2% with Paleum pratens, 8.5% with Festuca rubra, 5.4% with Ambrosia elatior, 7.5% with Miscanthus sinensis, 8.1% with Hormodendrum pedrosoi, and the average percentage of all the above was 6.5%. As for other common antigens, research is now being carried out.
  • 阿部 守邦, 柿沼 光明, 浅野 武彦
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 332-333,342
    発行日: 1962/10/30
    公開日: 2017/02/10
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    1) Intradermal tests with pollen extracts of timothy, orchard grass, meadow fescue, short ragweed and red pine were carried out in 37 allergic patients with bronchial asthma (34) and allergic rhinitis (3). Positive results obtained with each pollen extract were varing from 5.5 to 24% in the allergic patients and from 0 to 14% in non-allergic subjects. (Table) 2) Positive intradermal tests were obtained with house dust extract in 56.1% of 77 patients with bronchial asthma and allergic rhinitis, while 16.4 of 73 non-allergic subjects showed positive reactions. The allergic patients were divided in two groups, namely, the group of younger age less than 30 years and that of older age more than 31 years. positive reactions to house dust extract were observed more frequently in the younger group (83.8%) than in the older group (37.8%). In the non-allergic subjects 20.4% were positive in the younger group and 13.8% in the older group with same house dust extract. (Table 2) 3) The relationship between the allergenic potency in intradermal tests and the contents of total nitrogen, protein nitrogen and polysaccharides were studied in 10 patients with bronchial asthma by use of 5 different house dust extracts. Dose-response curves of each extract, namely, the mean values of diameters of erythemas plotted against to A) dilutions in weight by volume B) polysaccharides contents C) protein nitrogen contents and D) total nitrogen contents, were shown. The allergenic potencies were widely different in each extract and could not be corrected by chemical measures.
  • 佐藤 靖雄, 寺尾 杉, 荒木 英斉
    原稿種別: 本文
    1962 年 11 巻 9-10 号 p. 334-335,342
    発行日: 1962/10/30
    公開日: 2017/02/10
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    To define the reacted level of the specific and none-specific reaction, intradermal skin test with many kinds of allergen extract solution are employed to 58 allergic rhinitis patients and 55 control groups. Resulting from the difference of the skin test data, clinically the color of intranasal mucous membrane and hereditary factors, we attempt to classify the allergic rhinitis to four groups.
  • 原稿種別: 文献目録等
    1962 年 11 巻 9-10 号 p. 336-342
    発行日: 1962/10/30
    公開日: 2017/02/10
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  • 原稿種別: 付録等
    1962 年 11 巻 9-10 号 p. App6-
    発行日: 1962/10/30
    公開日: 2017/02/10
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