VITAMINS

Online ISSN : 2424-080X
Print ISSN : 0006-386X

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Volume 13

Displaying 351-400 of 405 articles from this issue

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STUDIES ON THE INDUSTRIAL PRODUCTION OF FLAVIN ADENINEDINUCLEOTIDE (II) : EXPERIMENTS ON THE STABILITY OF FLAVIN ADENINE DINUCLEOTIDE IN THE MYCELIUM

Masakazu IZUMIYA, Kyubei MINOURA

Article type: Article
1957 Volume 13 Pages 593-594
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_593

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The stability of FAD in mycelia of Eremothecium ashbyii was found to be as follows. (1) When mycelia containing FAD were incubated at 37℃ for an hour in the phosphate buffer of pH 5.3 and 7.4,their FAD content changed from 1.36mg per g to 1.26 and 1.27mg per g respectively. (2) When wet mycelia containing FAD were dehydrated with six volumes of dry acetone, the FAD content was decreased from 6.29 to 4.17mg per g. After this sample had been stored in a desiccator at room temperature for six months, little change in the FAD content was observed. (3) When mycelia containing FAD were made vermiform and dried at 75-78℃ for four hours, or when they were dried up on a hot porous the for 1-2 minutes, the FAD content was decreased from 6.26mg per g to 4.45 and 4.51mg per g respectively. These samples were stored similarly for six months and similar results were obtained.

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THE EFFECT OF VITAMIN B_6 AND ITS ANTAGONISTS ON THE HEME BIOSYNTHESIS IN THE CULTURE OF RAT BONE MARROW

Kozo YAMADA, Shuhei OGAWA

Article type: Article
1957 Volume 13 Pages 595-597
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_595

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The effect of cycloserine, isonicotinic acid hydrazid, pyridoxal, 2-methyl-4-amino-5-hydroxymethylpyrimidine, and desoxypyridoxine on the heme biosynthesis in rat hone marrow was studied by using radioisotope Fe^<55>. 1) The incorporation of Fe^<55> into heme in vitamin B_6 deficient rats increased proportionally to increase in the amount of vitamin B_6 administered with the diet. The incorporation increased also in vitro by the addition of pyridoxal to the reaction system of vitamin B_6 deficient group. 2) Cycloserine, isonicotinic acid hydrazid, and desoxypyridoxine inhibited the incorporation of Fe^<55> into heme in vitro. The inhibitions could not be restored by pyridoxal. 3) The incorporation of Fe^<55> into heme was smaller in the rat administered with cycloserine, compaired with the control and it could not be restored by pyridoxal. 4) 2-Methyl-4-amino-5-hydroxymethylpyrimidine increased the incorporation of Fe^<55> in vitro.

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 598-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_598

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STUDIES ON THE EFFICIENCIES OF THIAMINE DERIVATIVES : (I) THE STABILITIES OF THIAMINE DERIVATIVES ADDED TO WHEAT FLOUR

Yasuto WATANABE, Yoshimasa FUJII, Sakae SUGANO

Article type: Article
1957 Volume 13 Pages 599-602
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_599

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Thiaminehydrochloride, thiaminedicetylsulfate, dibenzoylthiamine and thiaminemonorhodanate were added to various kinds of wheat flour and stored at room temperature for 30 days in summer, and then their stabilities were compared. The stabilities were found to be independent of the kind of flour. The stability was found to vary according to the kinds of derivatives.

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 603-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_603

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THE INFLUENCE OF SYNTHETIC DIET ON THE TOXICITY OF HYDROXYMETHYLPYRIMIDINE IN MICE

Tsuneo MURAKAMI

Article type: Article
1957 Volume 13 Pages 604-606
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_604

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Abderhalden observed that the toxicity of 2-methyl-4-amino-5-hydroxymethylpyrimidine (OMP) was greater in the mice fed DK diet than in those reared on the ordinary diet. The author examined the toxicity of OMP in pyridoxine deficient mice. When fed on synthetic pyridoxine-deficient diet for 5 days, the dose of OMP causing the death of 50 per cent animals fell to about 1/3.5 of that in normal animals, and the dose was smaller than that in the case with Dk diet.The time required for appearance of fatal convulsion by OMP was shorter in pyridoxine-dificient animals than in those with the ordinary or DK diet.

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STUDIES ON THE FLUORESCENT SUBSTANCES IN THE BLOOD (I) : ON THE FLUORESCENT SUBSTANCES INHIBITING THE DETERMINATION OF RIBOFLAVIN BY LUMIFLAVIN METHOD IN THE BLOOD

Mamoru SUGIURA

Article type: Article
1957 Volume 13 Pages 607-610
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_607

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The determination of riboflavin content of various animals by lumiflavin method has shown that there exist fluorescent substances which have a great influence on measure of riboflavin value. These fluorescent substances consist, chiefly, of substances having Rf 0.55 and 0.82. These fluorescent substances can be completely eliminated by the chloroform extraction and oxidation by potassium permanganate.

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STUDIES ON THE FLUORESCENT SUBSTANCES IN THE BLOOD : (II) IDENTIFICATION OF THE FLUORESCENT SUBSTANCES FOUND IN THE BLOOD

Mamoru SUGIURA

Article type: Article
1957 Volume 13 Pages 611-619
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_611

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The examination of the fluorescent substances in the blood by rabbit blood has made clear the fluorescent substances found in it. Five kinds of fluorescent substances are found in the blood besides riboflavin. The investigation has been pursued with the application of spot colour reaction derived from paper partition chromatography, spector examination, contrivance of development solvent and bioassay. The result has shown that folic acid derivative in violet fluorescent substance, 3-hydroxykynurenine in yellow-green fluorescent substance, kynurenine in blue fluorescent substance and protoporphyrin in red-brown fluorescent substance have been identified. In yellow-brown fluorescent substance, a substance which seems to have a relation with protoporphyrin has been presumed.

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 619-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_619_1

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 619-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_619_2

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STUDIES ON THIAMINASE (I) : PURIFICATON OF THIAMINASE II

Eiichi SAKAKIBARA, Masuyuki KATUMATA

Article type: Article
1957 Volume 13 Pages 620-624
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_620

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An attempt was made to purify the thiaminase II from the culture broth of Bacillus aneurinolyticus Kimura et Aoyama. A crude enzyme preparation was obtained by an osmotic concentration method as a precipitate at 25-60% saturation of ammonium sulfate. The crude enzyme preparation was dissolved in phosphate buffer (pH 7.4) and fractionated with several ion exchange resins. The enzymic activity of a protein solution which passed throuth the cation exchanger, such as Amberlite IR-120 or IRC-50 was decreased, while that of a solution which passed through the anion exchanger, such as Amberlite IRA-400 or IR-4B was considerably increased. Form the above results and the examination of the absorption spectrum of protein solutions, it was supposed that the crude enzyme preparation contained an enzyme-protein, metallic ions and an acidic substance having an absorption maximum at 250 mμ.

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 624-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_624_1

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 624-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_624_2

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1957 Volume 13 Pages 625-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_625_1

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 625-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_625_2

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 625-626
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_625_3

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 626-627
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_626

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 627-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_627_1

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 627-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_627_2

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 627-628
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_627_3

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 628-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_628_1

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Article type: Article
1957 Volume 13 Pages 628-629
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_628_2

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 629-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_629_1

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 629-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_629_2

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 629-630
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_629_3

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 630-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_630_1

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 630-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_630_2

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 630-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_630_3

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BACTERIAL AUXOTROPHS : ISOLATION, IDENTIFICATION, PRESERVATION AND MUTATION RATE

Byoji HAYASHI, Hideo NAKAYAMA

Article type: Article
1957 Volume 13 Pages 631-645
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_631

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 645-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_645_1

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 645-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_645_2

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 645-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_645_3

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 646-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_646_1

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Article type: Article
1957 Volume 13 Pages 646-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_646_2

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 646-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_646_3

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 646-647
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_646_4

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 647-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_647_1

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 647-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_647_2

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 647-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_647_3

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Article type: Article
1957 Volume 13 Pages 647-648
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_647_4

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[title in Japanese]

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Article type: Article
1957 Volume 13 Pages 648-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_648_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

Article type: Article
1957 Volume 13 Pages 648-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_648_2

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 648-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_648_3

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 648-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_648_4

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 649-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_649_3

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 649-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_649_4

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 649-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_649_5

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 649-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_649_6

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 649-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_649_7

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[title in Japanese]

[in Japanese]

Article type: Article
1957 Volume 13 Pages 650-
Published: 1957
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.13.0_650_1

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