VITAMINS

Online ISSN : 2424-080X
Print ISSN : 0006-386X

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Volume 10

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 69-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_69_2

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 69-70
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_69_3

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 70-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_70_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 70-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_70_2

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 70-71
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_70_3

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 71-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_71_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 71-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_71_2

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 71-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_71_3

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 71-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_71_4

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 71-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_71_5

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 72-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_72_1

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 72-73
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_72_2

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 73-74
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_73

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 74-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_74

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CLINICAL STUDIES ON VITAMINS OF B-GROUP

Katashi INOUYE

Article type: Article
1956Volume 10 Pages 75-83
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_75

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 83-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_83_1

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 83-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_83_2

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MUSCLE CHRONAXIE VALUES IN POLIOMYELITIS PATIENTS FOLLOWING TREATMENT WITH THE GLUTAMYLCHOLINE-THIAMINE INTRASPINAL INJECTION METHOD

Masatomo MIYAKE, Kazuo KINUGASA, Tokuzo KOOKA

Article type: Article
1956Volume 10 Pages 84-86
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_84

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Alterations in the chronaxie values were examined in poliomyelitis patients and experimentally infected poliomyelitis monkeys following intraspinal injection of glutamylcholine and thiamine. It was found that the muscle chronaxie approached normal values following treatment.

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STUDIES ON CHANGES IN THE SKIN TEMPERATURE IN POLIOMYELITIS PATIENTS AND EXPERIMENTALLY INFECTED POLIOMYELITIS MONKEYS TREATED BY THE INTRASPINAL INJECTION OF GLUTAMYLCHOLINE

Shigeo SHIMIZU, Sumio NAMBA, Kazuo KINUGASA, Yoshio MANDOKORO

Article type: Article
1956Volume 10 Pages 87-89
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_87

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A marked rise in skin temperature is observed following an intraspinal injection of glutamylcholine and thiamine in poliomyelitis patients. The skin temperature was examined from the time of onset to full recovery in experimentally infected poliomyelitis monkeys. Changes in the skin temperature following intraspinal injection of glutamylcholine were also examined.

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 89-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_89_1

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 89-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_89_2

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CHANGES IN THIAMINE IN THE DEVELOPING CHICK EMBRYO

Toshiro KUBOYAMA

Article type: Article
1956Volume 10 Pages 90-93
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_90

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Thiamine metabolism was followed in developing chick embryos. There is no change in the total thiamine content during the entire course, but with development of the embryo, thiamine is transferred to the body of the chick and it is in the bound form. With development of the amnion and yolk sac, there is a gradual decrease in the free form, but the thiamine present in the amnion and amnionic fluid is for the greater part, the free form. The thiamine content of the chick increases with development and is found in the greatest quantities in the brain and muscles. The other organs in the order of their thiamine content are the heart, liver and intestines.

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THE CAROTINOIDE CONTENT OF COLOSTRUM

Kunie KANEDA

Article type: Article
1956Volume 10 Pages 93-95
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_93

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The carotin and vitamin A levels of the blood of the mother was examined prior to and postpartum. Before delivery, the carotin level is high and vitamin A is reduced and this relationship becomes reversed postpartum. In the later stages of pregnancy, liver dysfunction is seen. It is thus suggested that the mechanism by which large amounts of carotinoide appear in the colostrum is based on a disturbance in the transformation of vitamin A from carotin resulting due to a liver dysfunction occurring as a part of pregnancy toxicosis.

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 95-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_95_1

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 95-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_95_2

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STUDIES ON THIAMINE-DECOMPOSING THERMOSTABLE FACTORS : (III) ISOLATION OF A THIAMINE-DECOMPOSING THERMOSTABLE FACTOR FROM LEAVES OF SWEET POTATO

Sadahito SAKAMOTO

Article type: Article
1956Volume 10 Pages 96-98
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_96

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After extracting the thiamine-decomposing thermostable factor (SF) from leaves of sweet potato (I pomoea batatas) with several organic solvents, SF was transferred to ethyl acetate layer, from which it was isolated as yellow needles. The crystals were identified as isoquercitrin by determining melting point, paper chromatogram, absorption spectrum, elementary analysis, and preparing phenylosazone, as well as acetyl and methyl derivatives. Thiamine-decomposing activity of some flavonoids, e.g. isoquercitrin, is accerelated by manganese and the element was detected in the leaves by spectroscopic analysis.

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 98-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_98

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REACTION OF THIAMINE AND ITS PYRIMIDINE MOIETIES WITH 2,4-DINITROFLUOROBENZENE

Chikataro KAWASAKI, Shigeru AONUMA, Tsutomu MIMURA

Article type: Article
1956Volume 10 Pages 99-102
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_99

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The formation of dinitrophenyl derivatives from thiamine and its pyrimidine moieties by reaction with 2,4-dinitrofluorobenzene (DNFB) in alkaline solution was investigated. Thiamine was easily converted into the dinitrophenyl derivative of its thiol-form. 2-Methyl-4-amino-5-aminomethylpyrimidine and 2-methyl-4-amino-5-hydroxymethyl-pyrimidine were also quantitatively transformed to their dinitrophenyl derivatives, while 2,5-dimethyl-4-aminopyrimidine was recovered unchanged from the reaction mixture with DNFB. Thus the amino group at the 4-position of pyrimidine moiety of thiamine was proved inert to DNFB. These dinitrophenyl derivatives are separated and identified more easily by paper chromatography, compared to their parent substances.

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THE ESTIMATION OF COCARBOXYLASE IN BLOOD OF BERIBERI AND SOME OTHER DISEASES

Susumu YAMASHITA

Article type: Article
1956Volume 10 Pages 102-107
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_102

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There have been many reports on the content of the free and combined formes of thiamine in blood of verious diseases, but only a few which directly estimated cocarboxylase in blood of patients. The author was able to determine cocarboxylase and the so-called cocarboxylase index in blood successfully, using brewers' yeast. The results can be summerized as follows : 1) Cocarboxylase in blood naturally is diminished in the blood of beriberi-patients, but not in cases of ankylostomiasis and diabetes mellitus, although beriberi-alike hypaesthesia in extremities is found very often in latter diseases. 2) The manifest decrease of cocarboxylase in blood was found in pulmonary tuberculosis and malignant tumors, especially cancer of stomach, too. 3) In hepatic diseases the cocarboxylase index usually was not differed from that in healthy people. For the esterification of thiamine with phosphoric acid the liver function might not be excluded entirely but some other important factor must be taken into consideration.

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 107-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_107_1

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 107-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_107_2

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STUDIES ON PANTOTHENIC ACID METABOLISM IN LIVER DAMAGE : (I) THE URINARY EXCRETION OF PANTOTHENIC ACID IN NORMAL SUBJECTS AND IN PATIENTS WITH LIVER DISEASES

Tatsuyuki UESHIMA

Article type: Article
1956Volume 10 Pages 108-114
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_108

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The urinary content of pantothenic acid (PaA) was measured using Lactobacillus arabinosus 17-5. The microbiological assay for PaA was essentially similar to that of Skeggs. The urinary content of PaA of patients with various liver diseases was less than that of normal subjects. The increase of urinary PaA following an intramuscular adminstration of 20mg Ca-PaA was also less marked in patients with liver diseases, but the increase was more marked in patients with severe hepatic damage in comparison with that of normal subjects. The simultaneous intravenous infusion of 20 ml of 40% glucose solution caused a definite decrease in urinary PaA following the administration of 20 mg Ca-PaA in normal adults, but slight increase in most patients with liver disease.

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STUDIES ON ANTIOXIDANTS FOR VITAMIN A : (XX) EFFECTS OF PHENOLDISULFIDES ON THE STABILITY OF VITAMIN A

Goichiro KATSUI, Hiroshi KUYUMA

Article type: Article
1956Volume 10 Pages 115-117
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_115

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Investigations on the antioxidant activity to vitamin A of phenoldisulfides synthesized by the authors indicated that the activity of the compounds tested were generally weak, except thymoldisulfide and mono-t-butyl-p-cresoldisulfide which showed a considerable activity. It was, however, found that these disulfide compounds had the effect for protecting vitamin A from oxidation by removing such metal ions as copper ion promoting the oxidation of the vitamin.

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 117-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_117

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STUDIES ON THE LIPOTROPIC ACTION OF N-CARBOBENZOXY-L-GLUTAMYLCHOLINE

Nobuo WATARAI

Article type: Article
1956Volume 10 Pages 118-124
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_118

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The lipotropic action of N-carbobenzoxy-L-glutamylcholine was studied in the white rat from the standpoint of its effect towards the hepatic enzyme system and chemical analysis of liver fat. It was found that N-carbobenzoxy-L-glutamylcholine intensifies the activity of the transmethylase and cholinoxidase and prevents reduction of the phospholipids (especially lecithin) and inhibits deposition of neutral fat in the liver.

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 124-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_124_1

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 124-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_124_2

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 124-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_124_3

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DETERMINATION OF VITAMIN C

Shuntaro OGAWA, Eiichi HIRAOKA

Article type: Article
1956Volume 10 Pages 125-129
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_125

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 129-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_129_1

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 129-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_129_2

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 129-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_129_3

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[title in Japanese]

[in Japanese]

Article type: Article
1956Volume 10 Pages 130-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_130_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 130-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_130_2

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 130-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_130_3

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 130-131
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_130_4

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 131-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_131_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 131-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_131_2

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 131-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_131_3

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1956Volume 10 Pages 132-
Published: 1956
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.10.0_132_1

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