VITAMINS

Online ISSN : 2424-080X
Print ISSN : 0006-386X

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Volume 21

Displaying 101-150 of 341 articles from this issue

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 193-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_193_3

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ELECTROLYTE METABOLISM IN PYRIDOXINE DEFICIENT RATS

Keisuke TSUJIOKA

Article type: Article
1960 Volume 21 Pages 194-196
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_194

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In the previous paper it was found that pyridoxine deficient rats exhibited a significantly impaired water metabolism. Since water balance and electrolytes metabolism bear a close relationship, it is of interest to study electrolytes metabolism in this deficiency. This paper presents data on serum, liver, brain, kidney and muscle contents and urinary excretion of sodium and potassium in pyridoxine deficient rats. After administration of NaCl, urinary Na and K excretion in the deficient rats was not different from that in control animals. Pyridoxine deficient rats, when administered with KCl, excreted more Na than controls did. Normal rats when injected with pyridoxal, excreted more Na and K. In the deficient animals there was found a marked elevation of muscle Na and a definite reduction of muscle K, but was without any alterations in Na and K contents in liver, brain, kidney and serum.

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 196-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_196_1

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 196-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_196_2

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SOME PHYSIOLOGICAL ACTIONS OF ETHYLTHIAMINE

Tadashi SHIMIZU

Article type: Article
1960 Volume 21 Pages 197-201
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_197

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Recently Aramaki found that 2-ethylthiamine had nearly the same growth-promoting activity as thiamine in young rats, confirming the result obtained by Schulze. But Aramaki, and Kusch et al. observed that when rats were injected with ethyl thiamine their liver showed only a little increase in the cocarboxylase activity, and Aramaki et al. confirmed that the cocarboxylase activity of ethylthiamine pyrophosphate was only one twelfth to one fifteenth that of thiamine pyrophosphate. Previohsly we found that the daily injection of 20μg of ethylthiamine had the same growth-promoting action as that of 20μg of thiamine for mice fed with thiamine deficient diet for 18 days. Moreover, the liver homogenate of mice injected with ethylthiamine for a long time showed nearly the same endogenous respiration as that of mice treated with thiamine. Using washed liver homogenate of thiamine deficient mice we compared the respiration-stimulating activity of ethylthiamine pyrophosphate with that of thiamine pyrophosphate and confirmed that the former had a much lower activity than that of the latter. Finally, using the brains of thiamine deficient mice we compared the catatorulin effect of ethyl thiamine with that of thiamine and found that here again the activity of the former was much weaker than that of the latter. The above results could not explain the reason of growth-promoting effect of ethylthiamine.

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 201-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_201_1

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 201-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_201_2

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THE EFFECT OF PYRIDOXAL PHOSPHATE FOR VOMITING OF PREGNANCY

Mieko OOI, Hama INABA

Article type: Article
1960 Volume 21 Pages 202-203
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_202

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An administration of pyridoxal phosphate for twenty pregnant women suffering from the vomiting caused an improvement of the syndrome. Pyridoxine and pyridoxamine phosphate was also effective, but their effects were somewhat inferior to that of pyridoxal phosphate.

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STUDIES ON THE RIBOFLAVIN CONTENT AND PHOSPHATASE ACTIVITY OF THE MILK IN VARIOUS ANIMALS

Kazuo HOTTA, Isao ISHIGURO, Zyunko NAITO, Kimi TANAKA

Article type: Article
1960 Volume 21 Pages 204-208
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_204

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The relationship of the total riboflavin, the ratio of 3 types of riboflavin and the phosphatase activity were investigated. The results showed that the total riboflavin and the alkaline phosphatase activity were much higher in the milks of cow and goat than those of other animals. In the former, the content of free riboflavin was relatively higher than FAD and FMN. On the other hand, FAD predominated in the milks of human, pig and dog, and free riboflavin was not recognized. FAD and phosphatase of the milk were contained in the butter milk fraction.

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 208-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_208_1

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 208-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_208_2

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 208-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_208_3

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ON THE RIBOFLAVIN DECOMPOSING BACTERIA IN HUMAN FECES : (II) RIBOFLAVIN DECOMPOSITION BY STRAIN 14-I

Masami SAKAKI, Koyata HAMADA

Article type: Article
1960 Volume 21 Pages 209-216
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_209

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The riboflavin decomposing action of Strain 14-I was pursued. It was revealed to be due to an enzymic system which could be adaptatively produced only in bacterial cells when they became in contact with riboflavin. The decomposition led riboflavin into its moieties, lumichrome and ribose, but it did not occur at all when unadapted cells were situated in a glucose containing condition. On the other hand, the organisms synthesized riboflavin in a riboflavin deficient medium.

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 216-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_216_1

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 216-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_216_2

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STUDIES ON FATTY ACID ESTERS OF FLAVINS : (I) RIBOFLAVIN TETRAPALMITATE

Kunio YAGI, Jun OKUDA, A.A. DMITROVSKII, Rikuko HONDA

Article type: Article
1960 Volume 21 Pages 217-220
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_217

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To obtain fat soluble riboflavin derivatives, the authors synthesized riboflavin palmitate by esterification of riboflavin with palmityl chloride. Riboflavin palmitate thus obtained is soluble in various organic solvents and neutral fat, but not in water. The melting point is 78.5℃. The absorption and fluorescence emission spectra of its alcoholic solution were studied and its Rf values for various solvents were also obtained. Then, chemical structure of the riboflavin palmitate was studied by the estimation of riboflavin, and palmitic acid in its molecule, elemental analysis, and the test of periodate oxidation. From the above experimental results, it was found that the riboflavin palmitate is riboflavin-2', 3', 4', 5'-tetrapalmitate.

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STUDIES ON CARNITINE : (III) A NEW MICRO METHOD FOR THE DETERMINATION OF CROTONOBETAINE CONTAINED IN CARNITINE

Den-ichi IKEDA, Taneyoshi YU, Naokazu SAKOTA

Article type: Article
1960 Volume 21 Pages 220-225
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_220

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A new micro method for the determination of crotonobetaine contained in carnitine was developed. The method is a very simple and precise one, and not interfered by carnitine at all. The procedure is as follows : To 10 ml of a sample solution containing not more than 0.20 mg of crotonobetaine in a test tube add 1 ml of 25% H_2SO_4 and immerse the tube into water at 10℃ for 10 minutes. Add 1 ml of N/50 KMnO_4,kept at the same temperature and mix well. Determine the absorbancy of the solution at 525 mμ against water just 1 minute after the mixing of KMnO_4. Make a blank test with the same volumes of the same reagents except substituting the sample solution with water. The crotonobetaine concentration of the sample solution is obtained by comparing the decrease in color (which is obtained by substracting the absorbancy of the sample from that of the blank) with the standard curve.

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 225-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_225

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STUDIES ON CARNITINE : (IV) STABILITY OF CARNITINE CHLORIDE IN CRYSTALLINE STATE

Den-ichi IKEDA, Taneyoshi YU

Article type: Article
1960 Volume 21 Pages 226-230
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_226

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With an attempt to know the stability of carnitine chloride in crystalline state, the crystals were allowed to stand in various conditions and it was carefully observed if any change in appearances, generation of odour, etc. took place, together with measuring the weight of the samples at intervals during the time. Futhermore, were determined the mp., the contents of trimethyl amine and crotonobetaine, and the acidity and also prepared in some cases the chloroaurate of the samples before and after being allowed to stand. All the results obtained followed that carnitine chloride, at least in high purity and in crystalline state, was stable and any change or decomposition was not found even after being allowed to stand in an atmosphere at 105℃ for 40 hours, or in a desicator for a year.

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STUDIES ON CARNITINE : (V) STABILITY OF CARNITINE IN AQUEOUS SOLUTIONS

Den-ichi IKEDA, Taneyoshi YU

Article type: Article
1960 Volume 21 Pages 230-236
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_230

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The possible decomposing reactions of carnitine in aqueous solutions are practically those in which either (a) trimethyl amine or (b) crotonobetaine is produced. Aqueous solutions of carnitine chloride, of 1 and 10 w/v % concentration and at various pH (0-11.6) were sealed in ampoules and heated in a boiling water bath or an autoclave at 125℃. The amounts of trimethylamine and crotonobetaine produced wer determined in connection with the time of heating. Both the reactions (a) and (b) followed the first order reaction and their Q_<10℃> (mean temperature 112.5℃) were constant, independently of the pH, and 3.1 and 2.5,respectively. The reaction velocity coefficients K_<100℃> at various pH were as follows : [table]

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EFFECT OF VITAMIN D ON THE METABOLISM OF THIAMINE : (IV) STUDIES ON THE PHOSPHATASE ACTIVITIES OF LIVER AND KIDNEY HOMOGENATES OF INDUCED RACHITIC RATS ON ESTERIFIED THIAMINE

Osamu NOSE

Article type: Article
1960 Volume 21 Pages 237-241
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_237

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The phosphatase activities of liver and kidney homogenates of normal and rachitic rats on esterified thiamine were investigated. As described in the previous paper the thiamine contents in induced rachitic rat liver were considerably lower than those of normal rats. However, it was found that phosphatase activities of liver and kidney on esterified thiamine were no difference between norml rats and rachitic rats. Therefore, this result suggests that the decrease of total thiamine content in the rachitic rat liver may not be influenced by these activities in the tissue.

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 241-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_241_1

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 241-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_241_2

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EFFECT OF VITAMIN D ON THE METABOLISM OF THIAMINE : (V) STUDIES ON THE PHOSPHORYLATION ACTIVITY OF THIAMINE IN THE LIVER HOMOGENATE OF RACHITIC RATS

Osamu NOSE

Article type: Article
1960 Volume 21 Pages 242-246
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_242

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The soluble fraction of liver homogenate of normal and rachitic rats was obtained by Spinco ultracentrifuge (100,000g, 60 min.), and the phosphorylating activity of thiamine in the fraction was studied. The reaction mixture contained thiamine (5μg), ATP (10^<-3>M) as a phosphate donor, Mg^<++> (10^<-3>M) and the fraction. It was found that the activities of the fractions of normal and rachitic rats showed almost no difference. This suggests that vitamin D has no effect on thiamine phosphorylating activities.

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 246-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_246_1

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 246-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_246_2

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 246-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_246_3

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1960 Volume 21 Pages 247-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_247_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

Article type: Article
1960 Volume 21 Pages 247-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_247_2

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[title in Japanese]

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Article type: Article
1960 Volume 21 Pages 247-248
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_247_3

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1960 Volume 21 Pages 248-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_248_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1960 Volume 21 Pages 248-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_248_2

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 248-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_248_3

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 249-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_249_1

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 249-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_249_2

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[title in Japanese]

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Article type: Article
1960 Volume 21 Pages 250-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_250_1

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[title in Japanese]

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Article type: Article
1960 Volume 21 Pages 250-251
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_250_2

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[title in Japanese]

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Article type: Article
1960 Volume 21 Pages 251-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_251_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

Article type: Article
1960 Volume 21 Pages 251-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_251_2

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[title in Japanese]

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Article type: Article
1960 Volume 21 Pages 251-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_251_3

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1960 Volume 21 Pages 251-252
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_251_4

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 252-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_252_1

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[title in Japanese]

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Article type: Article
1960 Volume 21 Pages 252-253
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_252_2

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 253-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_253_1

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1960 Volume 21 Pages 253-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_253_2

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[title in Japanese]

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Article type: Article
1960 Volume 21 Pages 253-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_253_3

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[title in Japanese]

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Article type: Article
1960 Volume 21 Pages 253-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_253_4

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Article type: Article
1960 Volume 21 Pages 253-254
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_253_5

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese]

Article type: Article
1960 Volume 21 Pages 254-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_254_1

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[title in Japanese]

[in Japanese]

Article type: Article
1960 Volume 21 Pages 254-
Published: 1960
Released on J-STAGE: December 22, 2017

DOIhttps://doi.org/10.20632/vso.21.0_254_2

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