色材協会誌
Online ISSN : 1883-2199
Print ISSN : 0010-180X
ISSN-L : 0010-180X
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82 巻, 6 号
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研究論文
  • 電気毛管乳化法による生体適合型ナノカプセルの調製
    酒井 秀樹, 福島 宏, 佐藤 真弓, 近藤 保, 酒井 健一, 土屋 好司, 阿部 正彦
    2009 年 82 巻 6 号 p. 231-236
    発行日: 2009/06/20
    公開日: 2009/09/20
    DOIhttps://doi.org/10.4011/shikizai.82.231
    ジャーナル フリー
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    The present paper proposes a novel preparation method of carrageenan-polyethyleneimine complex capsules in the submicron size range using the interfacial gelling reaction at W/O type emulsion. A W/O emulsion was prepared by adding dropwise aqueous τ-carrageenan solution into cyclohexane containing sorbitan monooleate through a microsyringe. Carrageenan gel particles were then prepared by adding the emulsion into a cyclohexane solution containing Ca AOT (calcium bis (2-ethylhexyl) sulfosuccinate) to cause gelation of aqueous droplets. The gel particles thus prepared were coated with polyethyleneimine to improve their stability in water. Capsules with sizes ranging from 100 to 300 nm were obtained when an apparatus for electrocapillary emulsification was used in the preparation step of W/O emulsion. The use of calcium salt of dimyristoyl phosphatidyl glycerol, a constituent of biomembrane, as gelling agent gave capsules of sizes in the submicron range.
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ナノテクノロジー講座（第III講）
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