昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
20 巻, 3 号
選択された号の論文の7件中1~7を表示しています
  • 小田島 梧郎, 栗原 稔雄
    1960 年 20 巻 3 号 p. 227-230
    発行日: 1960/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    Out of the 212 cases examined, those in which M. piriformis was divided into two muscular bundles of upper and lower by the penetration of N. fibularis (peroneus) communis were 42, , 19.8±2.74%, while those in which it was divided into three bundles of upper, middle and lower were 3, 1.4±0.81%.
    The length, width and thickness of M. piriformis were slightly larger in males than in females and the diameter of the muscular bundle divided into two was larger on the upper bundle than on the lower one.
  • 鈴木 文次
    1960 年 20 巻 3 号 p. 231-235
    発行日: 1960/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    1. The toxicity of 1-chloro-2-hydroxypropanesulfonic acid (COP) is extremely low.
    2. When higher concentrations of COP were administered, no significant effects on, the blood pressure and the respiration of rabbit were observed, however the cardiac pulse was enhanced moderatelly.
    3. The slight inhibitory effect on the pulse and the moderate contraction on the coronary artery were observed in the isolated heart preparation of rabbit.
    4. The moderate contraction of the peripheral vein of rabbit was observed.
    5. No appreciable effect was observed on the movement of the isolated smooth muscle preparation (ileum, uterus) of rabbit.
  • 大野 嘉郎
    1960 年 20 巻 3 号 p. 236-247
    発行日: 1960/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    1. In the present study, biological observation and pathohistological survey of the kidney were made on the mice inoculated introcerebrally with ectromeria virus in varying dilutions of 10-1 to 10-10
    2. Survival days of the groups received the inoculation of highly concentrated virus was short and this survival period became longer following the increase in virus dilution with wider deviation of individual survival days. Namely, the survival period became longer from the group received concentrated virus to the groups of lower concentrations.
    3. It is considered that the viremia caused by the inoculation of ectromeria virus invited the development of destrutive changes on the glomeruli, especially, on the epithelium of the renal tubuli on one hand and the enhancement of vascular permeability due to the circulatory disturbance on the other resulting in the appearance of fibrous reproduction as reactional and reparative processes against such chages.
    4. As for renal lesions, both tissue destructive and circulation disturbing changes existing together there was no basic difference between the glomeruli and the tubuli indicating their progress into indurated lesions.
  • 佐藤 忠邦
    1960 年 20 巻 3 号 p. 248-260
    発行日: 1960/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    1. Lesions produced on the osseous system, especially on the craneal bone, of the embyyonating eggs were investigated by loading of Nicotine in different concentration of 1 mg, 5 mg, and 7 mg/cc.
    2. Bothh external measurements and those of the sections of the craneal bone nearly always showed figures lower than those calculated by the rate of the dimiuntion in the growth of the femoral bone. And, the fact that there were the eggs of 1 mg and 5 mg loading groups of the 15th day and the 20th day of embyonation frequently observed with measurements comparable to those of the control groups, and that there were some eggs in which to transversal diameter of the craneal fornix showed increase among the eggs of 1 mg loading group, suggest that the findings of the craneal bone have different significance from those of the femoral bone though hydrocephalic changes were not remarkable.
    3 In the present experiment, incompleie chondroplasia was recognized on the eggs up to the 15th day of embryonation but the eggs on the 20th day of embryonation, especially those of 1 mg group, showed marked ossification in contrast to the control. It is considered that premature osseous adhesion further advances to the shortening or diminution of the craneal fundus indicating their resemblance to the findings of chondrodystrophia foetalis.
  • (特にマウス系統による差異と経胎盤性の影響について)
    伊藤 啓二
    1960 年 20 巻 3 号 p. 261-285
    発行日: 1960/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    Stated in the following are the findings of the studies made on the influence of 3 kinds of tetracycline compounds (tetracycline HCI, oxytetracycline HCl and chlortetracycline HCl) administered per os in á large dose (20.0 mg daily) on the growth, parturition, new borns and on the pathohistological findings of the liver and the kidney of developing mice.
    1. Weight increase of developing mice was inhibited in the order listed, CTC→OTC→TC. This tendency was stronger on the pure bred DDB strain than that on the hybrid mice on market.
    2. Tissue destructive influence on the liver and the kidney was in the order CTC→OTC→TC. This tendency was stronger on the pure bred than on the hybrid.
    3. Female mice of DDB strain on the 6th week after birth received much weaker influence of tetracycline compounds than that observed on the mice under rapid development.
    4. Growth of the litter born by the mating of mice under administration of a large dose of TC or OTC was better than that of the litter from the mice without the treatment. While, the growth of the litter born from the mice received CTC was poor demonstrating histological disturbance on the liver and the kidney.
    5. Administration of TC or OTC in a large dose on pregnant mice showed no influence on the birth rate, while the administration of CTC lowered it. In comparison with the mice received no treatment, some of the mice received those drugs showed retardation in the period from mating to parturition, but there was no difference in the birth rate of new horns.
  • 成沢 達郎
    1960 年 20 巻 3 号 p. 286-293
    発行日: 1960/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    In order to clarify the mechanism of allergic reaction and anaphylactic shock due to the administration of antibiotics and to study the prophylactic measures for such conditions, studies were made on the relationship between this allergic reaction and cirulatory autonomic function. Out patients selected at random were inquired of their experienec in having allergic reaction due to antibiotics, or the symptoms of neurocirculatory asthenia, beriberi or allergic constitution, and also their blood pressures were measured. On many of them, morever, including both sensitive and non-sensitive patients, circulatory autonomic function tests such as cold pressor test, TEAB intravenous injection test, Aschner's test, Czermak-Hering's test, Martient's test, postural test, , postural ECG test, were performed.
    The number of patients examined was 1, 057. Of these patients, 5 males (1.6% of the male patients) and 20 females (5.1% of the females patients) were found to have the experience of developing allergic reactions by taking antiotics, namely, 19 were sensitive to penicillin, 6 to streptomycin. Shock developed in one of them and in the 5 cases the reaction was severe close to develop shock.
    When the findings of the 25 patients were compared with those of the non-sensitive patients, the former had more symptoms of neurocirculatory asthenia and showed the symptoms of beriberi and allergic constitution more frequently.
    Out of the circulrtory autonomic function tests made, cold pressor test, Martinet's test, Ashner's test and postural ECG test were positive in the sensitive patients.
    This study suggested the participation of circulatory autonomic unbalance to the development of allergic reactions against antibiotics. Symptoms of neurocirculatory asthenia and the findings of above mentioned circulatory autonomic function tests seem to be highly valuable for the prophylaxis of allergic reaction, especially of shock due to administration of antibiotics.
  • 小松 晃, 市原 文彦, 市原 正雄, 国府 田中, 杉山 規矩夫, 野地 貞雄, 久木田 正夫, 柳沢 洋一, 糸川 正, 鶴田 嘉門, ...
    1960 年 20 巻 3 号 p. 294-295
    発行日: 1960/06/30
    公開日: 2010/09/09
    ジャーナル フリー
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