Studies on the titer of Antistreptolysin-0 (ASL-O) with bacterial culture of streptococci from the throat swab were performed on 182 patients with streptococcal infections among children, 49 cases of non streptococcal infectious group with 148 cases of control during 1964 and 1965.
Results were as follows :
1) Ninety two percent of non-streptococal infectious group showed the titer of less than 100 units in ASL-O.
2) In the control group, seasonal variation of positive rate on the culture for streptococci showed 28 % in winter while approximety 40 % in other three seasons. Highest rate for positive results of streptococci culture were obtained in the age of 8 years group.
The highest rate in the titer of ASL-O was observed in summer followed by fall, spring and winter in order. Also higher frequency of positive rate was seen among the age of 4 to 7 years in age.
3) In the streptococcal infectious group, following positve rsults were obtained :
Acute respiratory illness : bacilli 90.9%
ASL-O 24.1%
Scarlet fever : bacilli 70.6 %
ASL-O 29.4%
Poststreptococcic state : bacilli 60.6 %
ASL-O 72.7 %
Rheumatic fever : bacilli 37.5 %
ALS-0 87.5%
Acute glomerulonephritis : bacilli 43.5 %
ASL-O 78.4%
Vascular purpura : bacilli 66.7 %
ASL-O 62.0%
The average of titer showed highest in rheumatic fever followed by vascular purpura, poststreptococcic state, nephritis, scarlet fever and acute respiratory illness accordingly.
4) Whithin 4 th week of illness, titer raised up more than 250 units in 70.2 % of infectious group.
It started to decrease within one to four weeks after beginning the treatment and reached normal value within 11 months thereafter.
5) More rapid decreasing rate of, ASL-O titer was seen in the group treated with steroid and antibiotics than antibiotics only.
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