昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
27 巻, 3 号
選択された号の論文の6件中1~6を表示しています
  • 清岡 弘毅
    1967 年 27 巻 3 号 p. 175-184
    発行日: 1967/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    1 A histopathological study was conducted on lesions in rabbit heart upon parenteral administration of sodium nitrite known to be toxic through methemoglobin formation daily in doses of 40, 60 and 80 mg/kg for a short and long period.
    2. The fundamental changes consisted of disturbance in blood circulation, congestion (or hyperemia), causing degenerative changes of the parenchymal cells of the myocardium as the manifestation of hypoxia. However, these changes mainly consisted of granular degeneration, destruction and dissolution of myocardial fibers and seldom underwent necrosis, fibrosis and cicatrization, although scattered areas of round cell infiltration may be seen at the far advanced stage.
    3. Changes in blood vessels especially arteries simultaneously or slightly earlier than the changes above mentioned are characteristic. Arterial walls show vacuolization, porotic changes, and partial degeneration and atrophy. As the time factor sets in, PAS positive substance appears in the wall of small arteries and veins, infiltrating around the blood vessel and into the interstitial tissue between muscle fibers and showing imbibition of muscle fibers. Proliferation of fibers and a tendency of cicatrization is seen in this location.
    4. The lesions were more severe in long term administration than in short term administration, upon the use of a large amount than a small amount, and in left ventricular muscle, septal muscle, and right ventricular muscle in the increasing order.
    5. Concerning the process of myocardial cicatrization, it seemed to be of primary importance that hydrops-like sclerosis due to lesions in the blood vessel spreaded to interstitial tissue and parenchyma rather than that the injury to parenchymatous cells led to fibrosis.
  • 菅谷 修一
    1967 年 27 巻 3 号 p. 185-213
    発行日: 1967/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    Experiments were performed on the hip joints of young rabbits in order to set up the deformity of the femoral head.
    By employing the methods of arteriography, microangiography and Spalteholz's technique, it is cleared that the A. retinacularis superior is more apt to be injured by the deformity than the A. retinacularis inferior in the arterial pattern surrounding the femoral head.
    Clinically, two series of films by arteriography and intraosseous venography were taken in the 58 patients with hip joints diseases and following results were obtained.
    1. Arteriograms of the affected side show the prolongation of time in passing contrast media mostly in all cases and especially remarkable in the A. circumflexa medialis femoris.
    2. When a marked deformity is seen in the femoral head, the ascending branch of the A. circumflexa medialis femoris is apt to form a blind loop.
    3. A. retinacularis superior was successfully shown in 77 among 111 joints, and A. retinacularis inferior in 94 joints. The side of the cases in which they failed to be demonstrated were mostly the affected.
    4. On the intraosseus venography, the affected side in osteoarthritis def ormans showed marked prolongation of disappearing the contrast media.
    5. The distribution of the contrast media through the bone marrow can be divided into 3 types; the venous type, infiltrating type, and intermediate type. The former type is frequently seen in the healthy side, while the latter type in the diseased side.
    6. In secondary osteoarthritis def ormans of the hips, some cases were thought to have changes in the vasculature resulted from deformity of the femoral head.
    7. It was emphasized that the changes of the femoral head could be missed or diagnosed faultly unless roentogenography with contrast medium be done periodically.
    The size and course of the blood vessels may vary considerably amang different individuals. Therf ore, comparative examination in each patient should be carried out on both healthy and affected sides.
  • 第3報S型およびR型菌のCell wall構成成分に関する研究
    宮路 圭介
    1967 年 27 巻 3 号 p. 214-221
    発行日: 1967/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    R-type of L. acidophilus is sensitive to saline and trypaflavine, reacts positive to Millon's reagent and heavy metal ions and forms granular or rough colony, making chains of various lengths. These characters are not seen in S-type. It is the purpose of this paper to study the cell-wall components of S-type and R-type to see the difference between them, if any.
    Following results were obtained.
    1. The polysaccharides obtained from the cell wall of S-type and R-type showed the similar sedimentation curves with 2 peaks each other in the ultra centrifugation analysis.
    2. Employing the polysaccharides prepared by the author, no difference of antigenity was found between S-type and R-type by the agar-gel-diffusion technic of Ouchterlony, in which only a single precipitation line was found.
    3. Both in S-type and R-type, the monosaccharides of the cell wall were proved to be galactose, mannose, xylose, rhamnose and glucosamine. However the amount of rhammose of R-type seemed to be much smaller than that of S-type.
    As reviewed in the previous paper, it was possible to find several differences in the biological characters between S-Type and R-type of L. acidophilus. Besides, it was difficult to find any difference in the cell-wall components between the two types even by using highly purified polysaccharides in the precipitation reaction and paperchromatographic analysis. Minor difference in rhamnose concentration between them, however, leads us to suspect that some change may occur in the composition of some carbohydrate of the cell wall when S-type mutates to R-type.
  • 西山 了
    1967 年 27 巻 3 号 p. 222-247
    発行日: 1967/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    Varying values of blood ammonia in patients with uterine cancer and those undergoing gynecological operation were determined by Seligson's time diffusion technique. As regards the values before operation, compared with the values of the controls, the group of patients with ovarian cystoma or those with uterine myoma showed higher values, and these two groups had nearly the same values. The group of patients with extra-uterine pregnancy gave somewhat hig-her values, and that with uterine cancer showed still higher values.
    During operation, each of these values rose, but they began to fall immediately after operation. However, they continued to be high till the third day after operation, but returned to the values before operation on the twelfth day.
    There was a tendency that the severer was the case of operative invasion, the more significant was the rise of the values during operation, and the slower was their fall after operation. While under anesthesia, the tendency was that, the longer the loss of blood continued, the higher was the value of blood ammonia.
    When cases of blood transfusion and non-blood transfusion were examined, the former cases, with a few exceptions, showed a rise in the value of blood ammonia.
    Cases of radiotherapy did not show significant changes in the values of bmmonia. These patients who died of uterine cancer showed a significant rise in the value of blood alood ammonia at the terminal stage of cancerous cachexia immediately before death.
  • 奥村 悠貢, 田崎 功, 岡部 元昭, 宗近 宏次, 鈴木 勝彦, 内藤 八洲男, 羽山 忠良, 風間 和男
    1967 年 27 巻 3 号 p. 248-251
    発行日: 1967/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    Histological examination was carried out to compare the findings of metastasis developed in the irradiated and not irradiated lung tissues.
    It was clear that there was some fibrosis in the walls of the alveoli of the irradiated tissues either with or without metastasis. No further differences were however found in the tissues between these two groups.
  • 土岐 裕, 高田 亮, 本多 俊晴, 中川 良平
    1967 年 27 巻 3 号 p. 252-256
    発行日: 1967/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    A case with vanishing tumor of the lung, associated with complete A-V Block and Adams-Stokes Symptome was reported.
    A 60-years-old woman was adminitted with the the chief complaint of hypertension of four months duration and frequent attacks of faint of one month duration. X-ray films of chest showed evidence of cardiomegaly and loculated fluid (so-called vanishing tumor) in the right transverse and right oblique fissures. A diagnosis was made of congestive heart failure due to hypertensive heart disease. A X-Ray film of chest taken 8 days after initiation of treatment showed complete disappearance of the suspected tumor.
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