昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
21 巻, 2 号
選択された号の論文の11件中1~11を表示しています
  • 脇阪 一郎, 山口 直, 高木 辰男
    1961 年 21 巻 2 号 p. 79-83
    発行日: 1961/05/28
    公開日: 2010/11/19
    ジャーナル フリー
    In this paper, the authors report on the cases of occupational dermatitis which were recently observed. These cases are the contact dermatitis by Penta chlorophenol (P.C.P.) which were observed in some electric company. The patients are anexperienced factory girls who are about 20 years old. The common symptoms are erythema and edema one the exposed skin, and manifest urinary urobilinogen. Manifest eosinophilia was observed in the one of these patieants. After the recovery from dermatitis, when the patients return to their posts, the dermatitis acutely grew worse. The reaction of p.c.p. was 100% positive in patch test, therefore, these cases were diagnosed as contact dermatitis by p.c.p.
  • 井上 房江
    1961 年 21 巻 2 号 p. 84-89
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    In order to prove the effect of the air pollution on the respiratory organs or the inhabitants in the industrial city, this report surveyed the concentration of the suspended fine dust in doors and out of doors at several districts in Kawasaki city and at the same time the pneumoconisis examination was made for the inhabitants in the factory districts, where the concentration of dust in the air showed comparatively high percentage.
    The following result obtained:
    1) The concentration of the suspended dust in the air on the streets of the factory districts showed average 500 particles per cubic centimeter (c.c.) a year and in some places, that stood 800-1000 particules per c.c., that is the allowable limit of the harmfull affairs. In such districts the concentration of the suspenbed dust in doors differed little from the dust concentration on the street and showed higher percentage than the hyginical allowance. In comparison with the fact that the percentage of ashes in the falling dust was about 50 percent in the residenral districts, that was high 70 percent in these factory districts. As to the quantity of dust, the inhabitants in the factory district were exposed to the several times as many as the inhabitants in residental districts.
    2) The 47 percent of the people who had lived more than for ten years in the factory districts, but who had never worked at the dusty affairs, had the symptons of pnemoconiosis, even they were not so serious. The rate of the attack with pneumoconiosis in the places where the suspended dust in the air stood 500-600 particles per c.c. was about 1.5 times as many as the rate of the attack in the places that had 400-500 particles per c.c.
  • 蔡 丁賛
    1961 年 21 巻 2 号 p. 90-97
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    Studies were made on the influence of B1 and related compounds thiamine propyldisulfide (TPD) and thiamine allyldisulfide (TAD) on nicotine hydrops as well as on B1 metabolism. Stated in the following are the results obtained thereof:
    1. B1 has an extremely weak inhibitory influence on the development of nicotine hydrops after 12th day of incubation, while TPD shows no such influence. The inhibitory influence of TAD is between the two.
    2. Excretion of B1 into the allantoic fluid is markedly reduced by the administration of nicotine 3.0 mg.
    3. When B1 was loaded under reduced B1 excretion, the excretion of B1 showed an increase in all stages of incubation in contrast to that of the loading of nicotine alone, but there was no comparison with the amount of excretion when B1 was loaded alone. Similar tendency was also observed with TPD. While, in the case of TAD, the total quantity of B1 excretion on the 15 th day and 18 th day of incubation in the eggs received combined administration was much larger than that of the control.
    4. On loading nicotine, the B1 content of liver showed a remarkable reduce, while the total B1 content of liver was markedly large on administration of B1, TPD or TAD alone and this ten-dency was stronger in the case of the administration of TPD or TAD than that of B1.
    5. Reduce in the B1 content of liver by the administration of nicotine was alleviated better by the administration of TPD or TAD, especially by TPD, than by the administration of B1.
  • 森谷 保昭
    1961 年 21 巻 2 号 p. 98-107
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    Penicillin induced variants were obtained from highly virulent B, anthracis strains 52 and Shikan as well as from weakly virulent H strain (Pasteur II) . Tests were made on their toxicity, biological and immunological characters, and at the same time, various studies were made on their reverse variaion. Stated in the follwing are the results obtained thereof:
    1. It took successive transplantation for 115 generations on the medium containing penicillin before obtaining the resistance of 20 u/ml.
    2. The strains which and acquired penicillin resistance showed either attenuation or loss of their virulence regardless to the virulence of starting strain.
    3. Penicillin resistant strains lost their capsule and showed remarkable weakening in their spore forming ability. And at the same time, they lost caseinase activity.
    4. This penicillin resistance was highly unstable and they reversed easily to the sensitive straints. But the changes accompanying the acquisition of penicillin resistance stated above were stable for a long period of time.
    5. Vaccination of so-called Sterne's saponin-spore suspension prepared by the use of penicillin resistant strain could prevent the death of the guinea pigs, rabbits and goats received the lethal dose of highly virulent strain.
    6. Above mentioned live vaccine prepared by the of penicillin resistant strain demonstrated virulence lower than Pasaeur I and accordingly, the loss of vaccination was much smaller. Whereas, its immunizing effect was much larger than that of Pasteur II vaccine and the inoculation of much smaller amount was sufficient for the production of immunity.
  • 堀田 恭子, 伊藤 赫, 巴 朔男
    1961 年 21 巻 2 号 p. 108-112
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    Employing the method previously described and by the use of Warburg's manometer, carbonic anhydrase activity was determined on the blood of various disorders. Mean carbonic anhydrase activity of normal blood was 46.056 μl (41-52 μl) . Enzymatic activity in the blood of patients suffering from pulmonary, cardiac and gastric disorders showed similar mean value but with broader deviation of individual values.
    Enzymatic activity in the blood of patients suffering from renal disorders showed such a broad range of 32-72 μl. In nearly all cases of hematic disorders, the enzymatic activity was some what lower than the normal value irrespective of the erythrocyte count. Enzymatic activity, changedd in reciprocal proportion to the count of erythrocytes.
  • 永田 和弘
    1961 年 21 巻 2 号 p. 113-122
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    A clincco-statistic observation was made on a total of 181 patients of so-called stiff shoulder reported to the author's clinic in the past 5 years. They occupied 1.36% of the total 13, 226 outpatients during the same period. Onset of the disease appears to be predominant during the seasons from spring to early summer. In the author's clinic, most of the patients reported in summer. Contrary to the other reports, males occupied only 46.4% and females 53.6%. As for the age of patients at the time of primary consultation, those on fifties were predominant. Those below 45 years were more among males and those above 46 were more among females. Those affected of both shoulders were 18.2%, right shoulder alone 44.8% and the left shoulder 37.0%. When this difference of right and left was observed by the difference of sex, the rate of males and females affected of both shoulders was 2: 1, while those suffered from only one side stiff shoulder were slightly more among females. The main complication noted was the disorder in the region of cervical vertebra necessitating detailed studies on this problem in future. Only 10 of them were found to have trauma which was a simple contusion in all cases.
    As for clinical symptoms, only few of them experienced the sudden attack of severe pain, and all cases followed chronic disease course. Numerous tender points were recognized on the regions of processus coracoides, anterior articular cleft and major tuber. As for motility, abduction and outward rotation were markedly disturbed indicating the presence of strong contracture at the positions of adduction and inside rotation.
    Main X-ray findings were the atrophy of bone on the region of major tuber (80.0%) and dark shadows observed on the part of the attachment of m. supra spinam tendon (48.8%) . These changes, however, are not necessarily characteristic to the so-called stiff shoulder. Arthrograms indicated the presence of the atrophy of articular capsule.
    Physicotheraphy, administration of antirheumatic preparations or intraarticular injections of steroid hormones were not so much effective. The use of abduction splint is highly recommended for the alleviation of pain as well as for the prevention of reflexive muscular contracture.
  • 永田 和弘
    1961 年 21 巻 2 号 p. 123-147
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    The author has obtained the following results after examination of the actions of antagonistic muscles of stiffened shoulders.
    I) Spontaneous-discharge, The frequency of the discharge was higher in the cases of stiffened shoulders than in the cases of non-stiffened shoulders, in particular, in the cases of so-called gojukata it was the highest at m. latissimus dorsi in contrast with other caused stiffened shoulders.
    II) Antagonist-discharge: The frequency is high in the cases of stiffened shoulders as well as of spontaneous discharge, in particular, it was frequently observed where the umbalance of the strength of holding muscles of shoulder joint is evident, but the more frequency was detected at m. latissimus dorsi in the cases of so-called gojukata. This fact shows, to the best of my knowledge, tnat the m, latissimus dorsi has strong functions to escape the pain by holding the upper extremity at adducted position, and at the same time, to prevent the instability of humerus-head which might appear through regressive changes of tendon of m. supra spinam.
    III) The author found that under the age of 34, relatively less cases were observed in which these two discharges appear at shoulders, while they often observed in the cases of so-called gojukata.
  • 五十嵐 義男
    1961 年 21 巻 2 号 p. 148-175
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    Application of antibiotics only after operation is not sufficient for the expectation of complete freedom from post-operative complications. While, the sterility of pharyngeal tube and gastro-intestinal tract is considered to be an ideal condition for surgical operations. In this connection, studies were made on the method of the application of antibiotics.
    First of all, a statistical observations were made on the pulmonary complications of the abdominal operations. During a period of 6 years and 5 months from January 1954 to May 1960, there were 70 cases of pulmonary complications out of the total 2, 093 cases of abdominal operations, namely, the rate of complication was 3.3%. Pulmonary complications were predominant among the patients of epigastric operations, especiallp, gastric cancer with a rate of 6.3%. More cases of complication were found in the age groups younger than 7 years old and older than 60 years old. And, the rate of pulmonary complication was especially high when children were anesthetized by ether open drop method.
    Based on the findings of statistical observations stated above, an investigation was made on the influence of Achromycin, Irotycin, Chloromycetin, Flagiomycin, Penicillin etc on the bacterial count of pharyngeal tube and gastro-intestinal tract. As the result of this investigation, the use of an antibiotic was found to inhibit bacterial growth at the time of operation. Generally speaking, however, there was a growth stronger than that before operation on the 3 rd day after operation neces-sitating the use of antibiotics at least for 3 days after operation. It was concluded, moreover, that a combination of 2 or 3 kinds of antibiotics is preferable to the administration of only one kind.
    Recently, it was become a fashion to apply mild anesthesia after operation in order to alleviate pain. But, this practice has given a rise in the rate of the incidences of pulmonary complication. Use of antibiotics may guarantee the safety application of this post-operative anesthesia.
  • 朴 相悟
    1961 年 21 巻 2 号 p. 176-194
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    Rabbits received the subcutaneous injection of Sodiumglucuronate (GNa) or Glucuronolactone (GL) for the observation of the influence of this injection on the bloodsugar value and the concentration of plasma K, Na and inorganic P. Further, investigations were made on the changes produced in the electrolytes at the time of the administration of Glucose, Adrenaline and KCI. Stated in the following are the results obtained thereof:
    1. Subcutaneous injection of GNa or GL produces a moderate elevation in the bloodsugar value of rabbits, while K and inorganic P concentrations of plasma show a lowering, but the concentration of Na remains unchanged. Teis injection causes a moderate increase in the K concentration of the heart of mice, but the K concentration of muscles remain unchanged.
    2. Administration of GNa or GL exerts an inhibitory influnece on the elevation of the bloodsugar value and the lowering of the concentration of plasmic K in the rabbits received the oral administration of Glucose. Lowering in plasmic P concentration, however, is enhanced by the injection of GL. K concentration of the heart and muscles of the mice received oral administration of Glucose receives no influence by the subcutaneous injection of GNa or GL. Plasmic K concentration of the rabbits received the subcutaneous injection of Adrenaline is lowered and the concentration of inorganic P is lowered temporarily but is restored normal. While, K concentration of the heart of mice received Adrenaline injection shows an elevation. Administration of GNa inhibits the lowering of K concentration in the rabbits and both GNa and GL retard the restoration of P concentration lowered by Adrenaline injection. Elevation in the K concentration of the heart of mice caused by Adrenaline injection is inhibited by the administration of GNa or GL.
    3. Intraperitoneal injection of KCl causes an elevation in the plasmic K concentration of rabbits and moderately lowers the concentration of inorganic P. Administration of C Na moderately inhibits this elevation of K concentration but does not influence on the lowering of inorganic P concentration. Elevation in the K concentration of the heart, muscles and the liver of mice received KCl is moderately inhibited by the administration of GL.
    In short, Glucuronic acid gives an evident influence on the electrolyte metabolism (especially K) of the rabbit's plasma and the visceral organs of mice.
  • 小松崎 茂
    1961 年 21 巻 2 号 p. 195-204
    発行日: 1961/05/28
    公開日: 2010/09/09
    ジャーナル フリー
    Accidental deaths due to the compression of the chest by blunt onjects or by the burying in sand or soil are encountered not infrequently, but as it is extremely rare to employ them as the means of killing, descriptions on the traumatic asphyxia in the text books of legal medicine are rather simple.
    Employing the corpses of traumatic asphyxia (caused by the compression of the chest) occurred in the past decade in Tokyo, a statistic observation was made on the relationship of the mechanism of the assaulting objects causing the compression and the findings of corpses, and at the same time considerations were given on each case of the corpses. Stated in the following are the results obtained thereof:
    1. The action of assaulting objects in traumatic asphyxia can be classified into two major groups of one two-dimentional compression (pinned under the object) and multi-dimentional compression (buried in the sand) . Dermal congestion caused by pressure, in the case of two-dimentional compression, appears on the sides which do not receive oppression.
    2. The most important finding for knowing the mechanism of the assaulting object in the case of the corpse died of two-dimentional compression is the dermal congestion caused by pressure. In many occasions, the dermal congestion can tell the position of the person at the time of receiving the fatal blow.
    3. In the case of multi-dimentional compression, it is impossible in many cases to judge the position at the time of the fatal blow, but if there is a gradual spread of the oppression, the portion of the skin received retard oppression and that received no oppression can be knows by the changes in dermal congestion caused by pressure.
    4. In the case of traumatic asphyxia and when there is an elapse of several, hours before the removal of the external oppression, the portion of the skin free from immediate oppression develops post mortem bulla caused by pressure.
    5. As for the histological findings of the visceral organs, they are the changes of sudden death (including suffocation) characterized by congestion and edema. Especially, the changes caused by anoxia owing to the acute circulatory disturbance are remarkable in the brain, cardiac muscles, liver, kidney and skeletal muscles. Emigration of eosinophiles in the spleen, moreover, and localized disappearance of adrenal lypoid are considered as the reactions against the stress.
    6. In the case of deaths caused by thoracicoabdominal oppression and when the fatal trauma is not known by external appearance and when it is known to be the visceral trauma on autopsy, they are mostly the cases of heaptic rupture.
  • 1961 年 21 巻 2 号 p. e1
    発行日: 1961年
    公開日: 2010/09/09
    ジャーナル フリー
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