昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
28 巻, 8 号
選択された号の論文の7件中1~7を表示しています
  • 今村 秀民
    1968 年 28 巻 8 号 p. 467-479
    発行日: 1968/08/28
    公開日: 2010/09/09
    ジャーナル フリー
    Immunological studies were made on transplantable cancer (Ehrlich ascites cancer) . Results were as follows.:
    1) Ehrlich ascites cancer cell was homogenized in a Frenchpress and was centrifuged for 5 min, at 2000 rpm. The alkaline soluble components had the specific antigenicity of Ehrlich ascites cancer cell.
    2) In the immuno-fluorescent staining of splenic lymphoid cell of transplantation-resistant mice (resistance was induced by the gradual increasing doses of the implants of cancer cells), specific fluorescence was found in the cytoplasma of the cell. The cancer specific antibody was present in the cytoplasma of splenic lymphoid cell.
    3) Adoptive immunity was established by transfer of splenic lymphoid cell.
    4) In the sera of rabbits immunized with Ehrlich ascites cancer cells, the cytolytic factors of tumor cell which differed from the antibodies demonstrated using the gel-diffusion technique and the passive hemagglutination test of Boyden.
  • 木嶋 健
    1968 年 28 巻 8 号 p. 480-495
    発行日: 1968/08/28
    公開日: 2010/09/09
    ジャーナル フリー
    It has been talked much about that stress promotes the genesis of the peptic ulcer since Selye's general adaptation syndrome. It is confirmed experimentally that psychological troubles have great influences upon the genesis of the ulcer. These psychological reactions by external stimulus are frequently influenced by the personality of receivers. The condition of autonomic nervous reaction has also an influence indirectly upon the genesis of the ulcer.
    From these points of view, the psychosomatical consideration is necessary in regard to the genesis of the peptic ulcer. And also, in postoperative complaints, psychosomatical factors are considered as the subject as compared with organic factors. And even if there are cases where organic factors are considered as the subject, it may be considered that psychosomatical symptoms appear on grounds of organic symptoms.
    The auther tried to investigate the patients' mentality, personality and autonomic nervous system psychosomatically on the genesis of the peptic ulcer and postoperative complaints. The patients with benign gastric lesions who were admitted to the Showa University Hospital for the purpose of gastrectomy were divided three groups ; preoperative, postoperative and pre- and postoperative group, and were examined by means of MMPI and mecholyl test.
    The results were as follows :
    1) Preoperative group : The patients with peptic ulcer showed more tendencies to neu-rosis and vegetative instability than those with other gastric lesions, and had much psychosomatical factors.
    2) Postoperative group : Neurotic tendencies were recognized in 80 % of male and 100 % of female of dumpers, and turned to patients with postoperative complaints and those with non-complaint. In mecholyl test, P types were seen in 65.4 % of dumpers and in 52.9 % of patients with postoperative complaints. So, postoperative complaints were closely related with vegetative instability.
    3) Pre- and postoperative group : Postoperative neurotic tendencies were larger than preoperative neurotic tendencies in postoperative complaints group, but smaller in Dumping syndrome group and non-complaint group. And, preoperative neurotic tendencies had great influence upon occurence of postoperative complaints, and particularly, in Dumping syndrome.
  • 熊谷 勝
    1968 年 28 巻 8 号 p. 496-514
    発行日: 1968/08/28
    公開日: 2010/09/09
    ジャーナル フリー
    More recently surgical patients in the elderly has been increasing in number because of the prolongation of the average span of a man's life. Surgical importance in geriatrics needs no emphasis. There are numerous problems to be solved in this field. The author studied adrenocortical response against surgical intervention due to increasing surgical cases in the elderly and in the purpose of preventing postoperative complications.
    Sixty one patients over 60 years old and 20 patients between the ages of 21 and 57 years were involved in this study. Preoperatively the urine 17-OHCS and the blood level of 17.OHCS were determined and Thorn's test was performed by administering 20 units of ACTH-Z. Postoperatively the urine 17-OHCS was measuaed everyday.
    The results wereoas follows :
    I. Preoperatively both the urinary excretion rate of 17-OHCS and the reduction rate of eosinophiles were much remarkable in the younger than in the elder patients. There was a tendency to the adrenocortical hypof unction with age.
    2. In the elder patients no different adrenocortical response was observed between benign and malignant diseases, however the reduction of the urine 17-OHCS was noticed in the malignant disease in the younger patients.
    3. Preoperatively the maximum rate of 17-OHCS appeared 8 hours later in the urine and 4 hours later in the blood after administering ACTH. Postoperatively the maximum rate of of 17-OHCS appeared 24 hours later in the blood and 48 hours later in the urine. It was cleared that there was some excretive delay of the urine 17-OHCS compare with the blood level of 17-OHCS.
    4. On the rate of the urine 17-OHCS before and after operation there was remarkable difference between younger and elder patients, but on the rate of the blood level of 17-OHCS, there was no difference between them.
    5. Judging from the results of the urine 17-OHCS (pre-and postoperatively), surgical intervention even in both younger and elder patients by gastrectomy was relatively greater than preoperative administration of 20 units of ACTH on the influence to the body.
    6. There was no difference in the elderly about the preoperative urine 17-OHCS between gastric resection for gastric ulcer and radical operation for gastric cancer. Postoperatively large amount of the urine 17-OHCS was admitted in cases of the radical operation for gastric cancer. These suggest that adrenocortical response would depend on the kinds of the surgical intervention.
    7. On the relationships between preoperative adrenocortical response and postoperative pulmonary complications, there was some tendency to the poor preoperative response of the adrenal cortex in cases of the pulmonary complications. So there are possibilities of the pulmonary complications in cases of the poor preoperative response of the adrenal cortex.
  • 赤坂 裕, 今村 一男, 甲斐 祥生, 中西 欽也, 丸山 行孝, 菅 孝幸, 近藤 常郎, 落合 元宏
    1968 年 28 巻 8 号 p. 515-519
    発行日: 1968/08/28
    公開日: 2010/09/09
    ジャーナル フリー
    We used GK-6166 on the 26 urological patients with pain and following results were obtained.
    1) Among 11 urological patients who had colic, 7 cases were effective and not effective in 4 cases.
    2) Among 11 patients who had urological operation, 9 were effective and not effective in 2.
    3) Against pain by urological examinations effective cases were seen in 3 out of 4.
    4) Only one patient among 26 had side effect showing dry mouth.
    5) Effect of the drug appeared about 15 minuts after the injection.
  • 西堀 実, 佐藤 哲平, 安藤 公信, 大野 貞夫, 門馬 満, H. Kumagaya
    1968 年 28 巻 8 号 p. 520-526
    発行日: 1968/08/28
    公開日: 2010/09/09
    ジャーナル フリー
    A case of idiopathic osteolysis in a forty-one year old man is reported. The etiology of this case could not demonstrated. Roentgenologic examination of the right foot revealed a concentric tapering of phalanx and metatarsal bone. The onset of the foot trouble began three years ago about the deformity on the right foot. Laboratory tests showed negative finding except the abnormal findings in phletismography, serum uric acid, and total protein. We were replaced this bone by artificial plastic bone. Microscopic examination of a section of the phalanx showed replacement of the greater portion of bone by connective tissue.
  • 鈴木 快輔, 西田 佳昭, 服部 博之, 福田 亮, 高橋 愛樹, 三富 静夫
    1968 年 28 巻 8 号 p. 527-531
    発行日: 1968/08/28
    公開日: 2010/09/09
    ジャーナル フリー
    We studied 131 cases of anal fistura, who were hospitalised between 1960 to 1966. Ave-rage age of the patients was 30.3 years old (53.4 was in the age of twenty) . Anal fistura was 22.3 % of all anal diseases examined during the same period.
    The most frequent chief complaints were discharge of the pus. The duration of history within a month was 20.6 %, within a year 68.7 % and over a year 31.3 %. Six, cases were over 11 years prior to admission. On the type of anal fistura, external incomplete anal fistura was most frequent and no cases of the internal complete anal fistura was experienced. In most cases the site of the anal fistura was posterior, especially in the position of 3 and 6 o'clock (34.8 %) . The fistulous track was usually under 2 cm in length. The longest one was 9 cm in length. 64.9 % of these patients had no treatments until admission and 47.8 % out of the treated cases had incisions of the abscess.
    Histopathological examination revealed 11 cases of the tuberculous lesion out of the 131 examined cases (8.4 %) and 2 cases out of them showed active pulmonary tuberculosis.
  • 内藤 八洲男, 志賀 貢, 田中 維大, 関 俊一, 時田 信彦, 北沢 卓, 菱田 豊彦, 竹内 方志, 北原 隆, 石川 信之, 鎌数 ...
    1968 年 28 巻 8 号 p. 532-539
    発行日: 1968/08/28
    公開日: 2010/09/09
    ジャーナル フリー
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