昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
24 巻, 12 号
選択された号の論文の6件中1~6を表示しています
  • 野口 岩男, 大坪 芳臣, 岡 保人
    1965 年 24 巻 12 号 p. 541-544
    発行日: 1965/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    Effect of the K+ concentration of outer medium on the injury potential in the ureter (Cabia cobaya) was measured and the results were compared with that of the sartorius muscle (Bufo vulgaris) . It is well known fact, that the injury potential of smooth muscles decays rapidly. Therefore the measurement was performed skillfully within 30 second after making the cut at the end of the ureter. Before each measurements, new cut was made on the ureter. In higher concentration of K+, the potential decreased proportionally to the log [K+] of the outer medium. Postulation of Nernst's theory was favored for the both results in the sartorius and in the ureter.
    But in the lower concentration of K+, the experimental results deviated from the theoretical. The potential indicated always lower value than the postulation of Nernst's formula. Such deviations are, according to Hodgkin's idea, owe to the existence of active transport of the K+ in the muscle cell. The deviation occures at [K+] =0.7m M/1 in the sartorius muscle, and [K+] =0.25m M/1 in the ureter. From these results, it can be supposed that the intensity of active transport is stranger in the sartorius muscle than in the ureter muscle.
  • 薄井 宏, 武重 秀雄
    1965 年 24 巻 12 号 p. 545-550
    発行日: 1965/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    A new roentgenographic diagnosis for subcutaneous rupture of the acilles tendon with a contrast medium was reported by Arner et al. in 1960. The method was evaluated in our clinic.
    The study were performed on eleven occasions on ten patients who had visited the Orthopedic clinic of Showa University Medical Center between May, 1961 and October, 1962. As to the rupture of the achilles tendon, nine cases were fresh subcutaneous and two long-standing, whose time interval between the injury and examination ranging one day to fifteen years.
    The contrast medium was composed of 5 ml. of 76% Urografin and 5ml. of 1% Hostacaene. The medium was injected into the mid-line of the dorsal surface of the tendon near the upper corner of the calcaneus in a prone position on the fluoroscopic table. When injected slowly into the space between the superficial paratenon and achilles tendon, the medium will spread over the dorsal surface of the tendon up to the rupture site, filling the gap or leaking out of the paratenon. Recognizing the ascending path of the medium fluoroscopically by continued injection, X-ray photographs were taken from two directions.
    A normal feature was represented by smooth contour along the achilles tendon (Fig. 2) .In the fresh cases of the rupture, the medium was distributed in a H-form between the both ends of the severed tendon (Fig. 3, 4), if the paratenon was fairly well preserved and in a triangle-form as an insuficient type of a H-form (Fig. 6) . When the ruptured ends were fringed or layered, the medium distributed into the irregular shaped spaces and then the shape of the ends may become obvious prior to the operation (Fig. 6) . In general, the extent and nature of the rupture could be estimated by the disribution of the medium. However, interpretatin should be done very carefully, when blood-clot was present in the rupture site, since it came out as a radio-opaque defect (Fig. 5) .
    In long-standing cases with cicatrization and marked adhesion, the medium was not distributed around the tendon (Fig. 9) . The complication of the rupture of the long plantaris muscle tendon might be able to be suggested.
    In conclusion, this method was useful not only for the diagnosis of clinically apparent rupture, but also for a supplementary diagnosis for long-standing cases or partial rupture (Fig. 8) .
  • 北沢 卓
    1965 年 24 巻 12 号 p. 551-563
    発行日: 1965/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    Amounts of urinaly allantoin and creatinine after total bcdy irradiation were measured by means of rat experiment.
    1) The creatinine excretion was well correlated to the body weight of the animal (r=0.754) . Daily excretion was 52.4±2.7γ per gram of the body weight.
    The amount decreased significantly on the 3 rd day after irradiation and returned to the normal level on the 6 th day; cysteine pre-treatment seemed to have no influence upon this course.
    2) The allantoin excretion was also correlated to the body weight of the animal (r=0.617) . Daily excretion was 249.2±26.3γ per gram weight of the animal.
    The amount increased significantly on the 1 st day after irradiation, then decreased from the 3 rd day until returned to the normal on the 6 th day. No increase was observed in the cystein pre-treated rat. However, the decrease was more remarkable than those in the rat not pre-treated.
    3) Allantoin-creatinine ratio was 4.82±0.40 in the control animal. This ratio increased on the 1 st day after irradiation, then decreased on the 2 nd and 3 rd day. The peak of this ratio might be an indication of injury soon after irradiation.
  • (とくにダンピング症候群を中心として)
    松石 正治
    1965 年 24 巻 12 号 p. 564-584
    発行日: 1965/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    Recently, more attention has been paid to postgastrectomy syndrome, especially to the Dumping syndrome, due to increasing gastrectomy for gastric or duodenal diseases.
    The author studied the changes of circulating plasma volume following test meal feeding in the gastrectomized patients. Also correlation study was made between the changes of plasma volume and complaint after gastrectomy and/or the rapidity of the passage through anastomosis by X-ray examination.
    The change of circulating plasma volume following the test meal feeding was determined by the modified methode of Gray and Frank, using radioactive Chromic Chloride 51CrCl3. The methode was proved to be correct after study with 5 normal men.
    Subjects for this study were as follows:
    Group A; twenty-six patients, who had no surgery, with gastric or duodenal diseases.
    Group B; one-hundred and seven, who had gastrectomy, without Dumping syndrome.
    Group C; forty-three with post plandial symptoms (Dumping syndrome) .
    It was demonstrated that the decrease of circulating plasma volume after the test meal feeding was the most severe in group C and the lowest value was obteined 30 minutes after the feeding. However, no relationship between the decrease of the plasma volume and the rapidity of the passage through anastomosis by X-ray was established.
    Through study was done in 43 dumpers (group C) in relation to their decreasing value of circulating plasma after the feeding.
    Three symptoms, (fatigue, sweating, and hot feeling) were proved not to be related with the change of plasma volume. On the other hand, the other symptoms, such as dyspnea, nausea, palpitation, dizziness etc. after the feeding were found to be the result due to the changes of plasma volume.
  • 田中 栄一, 杉田 幸二郎, 成沢 達郎, 伊藤 暢英, 今村 秀民, 後藤 晋, 及川 圭
    1965 年 24 巻 12 号 p. 585-590
    発行日: 1965/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    Recently, the periodic paralysis has been supposed to be a clinical syndrom, because it includes several kinds of etiologically different muscle paralysis on the extremities.
    As the mechanism of this paralytic attack, it was reasonable to presume that the diff erance of potassium concentration between intracellular and extracelluar space in muscle influenced strongly on resting membrane potential of the cells. Many of the idiopathic cases reported previously were accompanied by hypokalemia.
    A peculiar case with the periodic paralysis in male of 30 was presented. The characteristic features in this case were non-f omilial occurrence, normokalemia and euthyroidism. So far as our studies are concerned, this may be a case of so-called normokalemic periodic paralysis.
  • 中島 康朝, 山下 友義, 矢吹 栄佑, 清田 卓也, 薄井 宏, 武重 秀雄, 金 栄〓, 小森山 忠
    1965 年 24 巻 12 号 p. 591-597
    発行日: 1965/03/28
    公開日: 2010/09/09
    ジャーナル フリー
    A case of malignant melanoma in 68-year-old male was reported. The metastasis of malignant melanoma (histologically amelanotic type) in the vertebrae were clinically discoverd through surgical specimen.
    The autopsy revealed the numerous metastasis foci in the liver, both lungs, vertebrae and marked melanosis of the entire large intestines. Inspite of complete histological examination of the whole organs, including the large intestines, the possible site of the primary focus could not be found.
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