巻号一覧
40 巻, 1 号
選択された号の論文の14件中1～14を表示しています
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藤田 力也, 倉俣 英夫, 川瀬 定夫, 大栗 茂芳, 小林 明文, 山村 光久, 藤田 安幸, 中神 誠一, 菅田 文夫, 山辺 博, 白 ...1980 年 40 巻 1 号 p. 1-6
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーPDF形式でダウンロード (567K) -
―吉田肉腫における―長谷川 一彦1980 年 40 巻 1 号 p. 7-14
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーYoshida sarcoma was, first, transplanted on the right side of the back of Donryu rats. Thereafter the second tumor was transplanted on the left side of the back after interval of 1 to 21 days. Unsuccessful inoculation of the second tumor was regarded as tumor rejection. In this system, rejection was made up three days after the transplantation of the first tumor. In order to evaluate the rejection numerically, whole irradiation with 60Co-γ-ray was added to suppress some extent of the rejecting power. Results are as follows.
1) Establishment of rejection was 3 days after first tumor transplantation.
2) When rats were irradiated before the establishment of tumor rejection, the extent of establishment was decreased. The earlier irradiation was performed, the more this establishment prolonged.
3) Rejection was suppressed, when 50 cads was irradiated immediately after the establishment of rejection. Irradiation of 50 rads on 3 days after the establishment of rejection failed to suppress rejection, while irradiation of 100 rads suppressed rejection.
4) The smaller the dose was, the earlier the rejection recovered.
5) The extent of rejection was increased by 2 times of inoculated second tumor cell.
6) This extent of rejection was gradually increased from the time of inoculation of first tumor.抄録全体を表示PDF形式でダウンロード (911K) -
大野 正昭1980 年 40 巻 1 号 p. 15-26
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーObservation was made on functional aspect of ligament structure by scanning electron microscopy of micro structure of knee joint ligament (anterior and posterior cruciate ligaments, internal and external collateral ligaments) .
Materials were human knee joint ligaments obtained from amputated legs of 23-76 year old patients.
Sites of observation were initiating part, middle part and attached part of a ligament.
Results are as follows.
1) On longitudinal section of ligament
Longitudinal section of ligament consists of bundles of collagen fibers which form ligament fibers and they are thick, presenting wavy flows.
2) On transverse section of ligament
Anterior and posterior cruciate ligaments are divided into various large and small section which have no apparent membrane as tendon bundle. Inside the division, small holes are observed which are considered to be related with nutritional supply of ligament.
On the other hand, different from other ligaments, internal collateral ligament consists of several layers without formation of divisions.
3) On initiating part and attached part of ligament
Tibia attached parts of anterior and posterior cruciated ligaments transfer ligament fibers partly to knee cartilage, but most of them connects directly with bone.
As for shift of ligament to joint cartilage layer, whether or not ligament fibers connect with bone through cartlage layer is difficult to know.
At the initiating part of femur, ligament fibers mostly connect directly with bone fibers.
At the attached part of ligament to tibia, ligament fibers reach as far as around medullary cavity.
Ligament fibers of collateral ligament followed up just like in case of cruciate ligament, reach as far as around medullary cavity inside femur, tibia and fibula.
Clinically, ligament injury has various forms of injury and from above results of observation, in many cases of trauma, middle part of ligament is mostly cut and also liable to be excessively streched.
It is considered that ligament is apt to be injured because at forms divisions without membrane which corresponds to tendon bundle in tendon or because it forms several layers of fiber layer.
It is considered because of firm connection between ligament and bone that fracture is readily produced by injury.抄録全体を表示PDF形式でダウンロード (14661K) -
宮下 幸夫1980 年 40 巻 1 号 p. 27-40
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリー著者は前報でleucineが家兎の血液凝固能を亢進し, その機序はすでに合成されているvitamin K依存性凝固因子であるprothrombin, 第W因子そして第IX因子の動員による血中contentの増加によるものであろうと報告した。今回はvitaminK作用に拮抗するcoumarin誘導体を用いて実験を行ない, leucineがcoumarin誘導体による凝固能低下に拮抗し前報の推察を裏付け得たということを記述した。
leucineによる上記凝固因子増量の機序に対して, 前報ではたんに動員によるものであろうとしたが, leuCineは考察で述べたごとく短時間で肝細胞その他の細胞内にはいることから, leuCine投与による凝固能亢進にleucineの肝細胞への侵入がどのような意味を持っているのかについて, こんご調べていきたいと考えている。抄録全体を表示PDF形式でダウンロード (1136K) -
安達 浩行, 鶴岡 延熹, 鈴木 和郎, 香川 宗也, 清水 盈行1980 年 40 巻 1 号 p. 41-48
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーThe effects of some hormones, nucleotides and allopurinol on RNA synthesis were investigated in Shay granulocytic sarcoma.
Prednisolone stimulated in vitro and in vivo synthesis of RNA in granulocytic sarcoma cells. Manifest effects of androgens, estrogen and thyroid hormones on RNA synthesis were not observed. The adminstration of insulin caused an increase in the incorporation of 3H-uridine into RNA.
ATP accelerated the synthesis of RNA. Cyclic AMP did not stimulate RNA synthesis, but it had slight stimulatory effects on protein synthesis.
Allopurinol accelerated the incorporation of 32P orthophosphate into RNA, but did not the incorporation of 14C-adenosine into RNA. It was suggested that allopurinol accelerated the utilization of xanthine and hypoxanthine in RNA synthesis.抄録全体を表示PDF形式でダウンロード (809K) -
安達 浩行, 鶴岡 延熹, 鈴木 和郎, 日野 研一郎, 清水 盈行1980 年 40 巻 1 号 p. 49-54
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーDNA, RNA and protein are actively synthesized in bone marrow hematopoietic cells. The experiments of RNA synthesis with 3H-uridine and 32P orthophosphate suggested that RNA was mainly synthesized through salvage pathway of nucleotides in bone marrow cells.
In granulocytic cells, 3H-uridine was utilized more effectively for RNA synthesis than in erythroid cells. This result was explained by higher uridine kinase activity or lower UDP reductase activity in granulocytic cells.
The half life of m-RNA in granulocytic cells was about four hours, while the turnover of m-RNA in erythroid cells was thought to be very slow.抄録全体を表示PDF形式でダウンロード (557K) -
―特に下肢筋の変化との比較―東 慶紀, 猪口 清一郎, 木村 忠直, 阿尻 貞三1980 年 40 巻 1 号 p. 55-67
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーMyofibrous organization of the M. rectus abdominis of 9, one and a half year old rats which were subjected to running exercise on the treadmill, were examined. And the results were compared with controls and some lower extremity muscles of the same animals.
The following results were achieved :
1) In male, body weight of subjects and cross-sectional area of muscle venter were greater. In females the number of muscle fibers per sq. mm. and total number of muscle fibers were higher. On the other hand, the number of red fibers per sq. mm. was greater in males than in females.
2) Compared with the lower extremity muscles, cross-sectional area, number of muscle fibers per sq. mm. and total number of muscle fibers were always : most, gastrocnemius ; then tibialis anterior ; and rectus abdominis least. But the number ratio of red muscle fiber to white fiber of rectus abdominis and tibialis anterior were about 2 times greater than that of gastrocnemius.
3) Concernning the thickness of each muscle fibers of rectus abdominis muscle, white fiber was larger than red fiber and white fiber of male was larger than female in controls. Hypertrophy of the muscle fiber in experiments were so large in white fiber of male muscle and in red fiber of female muscle, so that the differences of muscle fiber size between male and female in experiments were excellent in white muscle fiber.
4) In control, the thickness of muscle fibers were larger in order of gastrocnemius, tibialis anterior and rectus abdominis. In experiment male animals, the white muscle fiber of tibialis anterior developed larger than that of gastrocnemius, and white fiber of rectus abdominis became equal to that of gastrocnemius.
5) It was recognized that the muscles examined showed the different reaction by running experiment, even though the muscles in the same animal.抄録全体を表示PDF形式でダウンロード (1217K) -
村居 真琴, 林 誠夫, 櫛橋 民生, 橋本 通, 木村 一成1980 年 40 巻 1 号 p. 69-74
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーEffects of inhibitors such as DFP and eserine, heat treatment and trypsin and triton x-100 treatment on cholinesterase (ChE) in dog brain and liver mitochondria and erythrocytes with acetyl-β-methylcholine (MeCh), butyrylcholine (BuCh) and tributyrin as substrate of true ChE, pseudo ChE and esterase, respectively were studied. pI 50's of DFP with brain ChE were 10-4.2 M in McCh, 10-7.2 M in BuCh and 10-5.2 M in tributyrin and with liver they were 10-7 M in BuCh and 10-7.2 M in tributyrin and with erythrocytes they were 10-3.5 M in McCh and similar to brain in BuCh and tributyrin. In case of eserine, pI 50's with brain were 10-7 in McCh, and 10-8 M in BuCh and 10-4 M in tributyrin and those with liver were almost similar to brain in BuCh and 10-3 M in tributyrin. In erythrocytes, they were similar to brain in McCh but when high concentration of eserine (10-3 M) was used, ChE activity was decreased to 50% in BuCh and no inhibition was observed in tributyrin. ChE activities of brain, liver and erythrocytes were disappeared within 4 minutes by heat treatment at 60°C with McCh and slight decrease was observed in 6 minutes with BuCh. By trypsin treatment for 30 minutes, ChE activities of brain and erythrocytes were decreased more than 80% with McCh and those of brain and liver were decreasd to 40% and 20% with BuCh, respectively. By treatment of 25% triton x-100, ChE was solubilized to 90% with McCh, 65% with BuCh in brain and to 90% with BuCh in liver.抄録全体を表示PDF形式でダウンロード (701K) -
山口 正志, 城之内 浩美1980 年 40 巻 1 号 p. 75-82
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーヌーナン症候群の二症例を経験したので報告した.本症候群は短軅, 翼状頸, 性腺形成不全, 外反肘及び眼の異常など特徴的な症状を有する疾患である.
症例1は8ケ月の男児.感冒にて外来受診時, 外表奇形を指摘されて入院した.症例2は8歳の男児, 本院形成外科へ顔面奇形を主訴として来院.当科へ染色体検査を目的として受診した.
両症例とも染色体は, 46, XY正常男子核型であった.症例1については成長ホルモン, 免疫学的検索等諸種精査したが特に異常はなかった.
本症候群の成因は不明である.頻度に関しても正確な統計はないが, 1/1, 000～1/2, 500といわれている.遺伝形式に関しても諸説があり, 大部分が散発例であることから染色体微細欠損説, 多因子遺伝説等がある.最近では常染色体優性遺伝, XとYの相同座位の突然変異かsubmicroscopic deletionが考えられている.
本症候群とTurner症候群の鑑別は特に重要である.抄録全体を表示PDF形式でダウンロード (2622K) -
滝川 宗一郎, 扇内 幹夫, 金 隆志, 平沼 晃, 丸山 俊章1980 年 40 巻 1 号 p. 83-86
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーRing injury of the finger is a special type of the avulsion or degloving injury. In our three cases, the degree of their injury and the therapy were different from each other. We used microsurgical technique for one of our cases, and the result was very satisfactory.
Case 1. “Decubitus” ulcer caused by pressure from a ring : A 56-year-old woman visited our clinic because her right middle finger had been swollen due to the pressure from a ring. The ring was removed with airtome, and we found a pressure ulcer beneath the ring. The wound healed primarily within three weeks.
Case 2. Complete degloving of all soft tissue without tendons : A 37-year-old man was caught his ring on his left middle finger on the edge when he jumped down to the ground from a body of a truck. Primary abdominal pedicle flap method was carried out, but the result was not so good.
Case 3. Complete avulsion of all soft tissue with the damage to both radial and ulnar digital arteries : A 53-year-old man was brought to our clinic sustaining a ring avulsion injury on his left ring finger. He was caught his ring on the edge of a heavy box as he was putting it down to the ground. Radial digital artery was anastomosed with microsurgical technique, and the circulation was recovered immediately. The functional and cosmetic result was very satisfactory.抄録全体を表示PDF形式でダウンロード (3276K) -
片岡 徹, 李 中仁, 鈴木 親良, 川内 章裕, 河村 一敏, 幡谷 潔, 舟木 正朋, 小林 建一, 東 弘志, 荒井 潔, 石井 淳一1980 年 40 巻 1 号 p. 87-92
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーA case of double carcinoma of the esophagus and lung was reported with review of the Japanese literature. This case was a synchronous double carcinoma and was statisfied with criteria of Warren & Gates. A literature survey was carried out on five clinical cases and fifteen autopsy cases with such double carcinoma of the esophagus and lung reported in Japan. About them, the characteristics, problems of surgical treatment and so on were discussed.
The patient was a man, aged 74 years and was admitted to our hospital with the chief complaint of vomiting. The X-ray and endoscopy of the esophagus revealed a elevated lesion of the middle thoracic esophagus. Biopsy specimens were taken from the lesion and were diagnosed as squamous cell carcinoma of the esophagus. The chest X-ray showed a round nodular shadow in the upper lobe of the right lung and we suspected a carcinoma of the lung. The esophageal carcinoma was resected radically and the lung tumor (histological finding : lung carcinoma) was treated with a conservative resection.
The pathological findings of these resected specimens were presented as follows ;
(1) The esophageal tumor was a elevated lesion, measuring 4.0 × 3.5 × 3.0 cm in size. Histologically, it showed adenoacanthoma, sm (depth of invasion) and stage 0 carcinoma (histological stage), so called early carcinoma of the esophagus.
(2) The lung tumor was a round and localized lesion, measuring 5.0 × 5.0 × 4.0 cm in size and histologically bronchiole-alveolar carcinoma.抄録全体を表示PDF形式でダウンロード (4830K) -
丸山 俊章, 高野 吉則, 池田 稔, 森 義明1980 年 40 巻 1 号 p. 93-96
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーTo the 12 male and 15 female cases (total 27) of osteoarthrosis of the knee, quadriceps strengthening exercise was given. The methods employed consisted of quadriceps setting exercise and straight leg raising exercise as isometric exercise, as well as a knee extension exercise with iron dumb-bells fixed on soles as isotonic exercise.
When the patients were trained three times or more a week at the hospital with the above exercise, the effect was evident in two weeks in the muscles, which were definitely reinforced in two months after the start of the exercises. The circumference of the thigh, paticularly in the part 10 cm. above the suprapatellar edge, was greatly enlarged in two months after the start of the exercise.
This was concidered due to the recovery of the vastus medialis muscle. The fluctuations in pains indicated that pains lessened remarkably in a month's passage after the exercise in many cases.抄録全体を表示PDF形式でダウンロード (402K) -
岩井 雅彦1980 年 40 巻 1 号 p. 97-101
発行日: 1980/02/28
公開日: 2010/11/19
ジャーナル フリーTwo cases of calcinosis cutis of the scrotum were experienced.
Case 1: a 31-year-old male had had multiple hard nodules on the scrotum of 2-year duration,
Case 2 : a 29-year-old male had had multiple nodules of 5-year-duration.
The histologic sections of the two cases revealed great number of massive and small granular substance which stained deep blue with H & E and black with Von Kossa's stain. They were surrounded by inflammatory infiltrate mixed with foreign-body giant cells or thick fibrosis. No cystic structure contained the granular substance was demonstrated.
Thus, the cases diagnosed as dystrophic type of calcium deposition. Nineteen cases available in the literature of Japan were reviewed.抄録全体を表示PDF形式でダウンロード (4530K) -
滝川 宗一郎, 小出 清一, 児玉 日出輝, 屋宜 公, 滝川 宗一郎, 小出 清一, 児玉 日出輝, 屋宜 公, 渋谷 正直, 世良田 和 ...1980 年 40 巻 1 号 p. 139-147
発行日: 1980/02/28
公開日: 2010/09/09
ジャーナル フリーPDF形式でダウンロード (1216K)
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