巻号一覧
18 巻, 4 号
選択された号の論文の15件中1～15を表示しています
- |<
- <
- 1
- >
- >|
-
第4編 マウスの分娩率, 育仔率及び産仔に及ぼす影響荒木 日出之助1958 年 18 巻 4 号 p. 269-278
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーThe effects of anti-tumor substances on the reproductive ability of the mice, such as the rate of delivery and the rate of foetus rearing have been studied. The following results were obtained.
(1) The rate of delivery was almost the same as control when they were observed for a long time. However, when they were observed for a shorter period (25 days) the group which received Nitromin, Azan, or Carzinophilin showed a low rate of delivery such as 30, 26.7% and 23.3% respectively, and the periods of pregnancy were longer than that of control, such as 34.6 days, 37.1 days and 39 days respectively.
(2) The fewer number and less body-weight foetus were produced when Nitromin or Carzinophilin was administered.
(3) The rate of foetus rearing was 67.6% when Nitromin had been administered while 60.6% when Azan, and 73.6% when Carzinophilin, which were considerably less than that of control.
(4) The low rate of growing was seen in the group which Azan or Carzinophilin was administered.
(5) In one case, foetus found with lacks the right rear paw and subcutaneous bleeding. and in four cases foetus found with subcutaneous bleeding.抄録全体を表示PDF形式でダウンロード (1305K) -
荒木 日出之助1958 年 18 巻 4 号 p. 279-282
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーIt is well known that anti-tumor substances inhibit the fissions and multiplications of malignant tumor cells. It is of interest to kow anti-tumor substances act upon the reprod-uctive cells, which have comparatively. strong power of fission.
The effects of anti-tumor substances on the testicles of mice following the administration of 0.5 mg of Methyl his (β-chloroethy) amine N-oxide hydrochloride and 1 mg of 8-Azaguanine have been studied. The following results were obtained.
Anti-tumor substances can cause transient inhibition of fission period. -1 he most serious effect in testicles were found in spermatogonia and spermatocyte, prespermatid and spermatid, while less effect were found in sertoli cells and interstitial cells, which were reversible. The most serious effects appeared between 3-5 days following the administration, and then recovered gradually and functions reappeared in the tenth day.抄録全体を表示PDF形式でダウンロード (4127K) -
荒木 日出之助, 外山 順一, 小島 宗康, 松田 英弌1958 年 18 巻 4 号 p. 283-285
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーTwo-tenth of mg of Nitromin, 1 mg of Azan, and 250 u of Carzinophyllin were administered to D. D.N mice for five consective daps. For measurement of liver tissue respiration, mice were slaughtered 24 hours after the suspension of administration.
In control group respiration rate (Qo2 : mm3/1 mg/1 hour) was 2.35, while Qo2 of the groupe which was administered 1 mg of Cobalt Greenpole (Co-g) five times, 0.1 mg of Co-g for five times, Nitromin, Azan, of Carzinophyllin was 2.18, 2.35, 1.61, 1.83 and 1.73 respectably. These suggesting disturbauces of liver function.
When Nitromin and 1 mg of Co-g were adminstered simultaneously, Qo2 was 2.33, and 2.35 in case of 0.1 mg of Co-g. When Azan and 1 mg of Co-g were administered simultaneously Qo2 was 1.99, while 2.30 in case of 0.1 mg of Co-g. When Carzinophyllin and 1 mg of Co-g were administered simultaneously Qo2 was 1.76, while 2.30 in case of 0.1 mg Co-g.
As shown in above results, the combined use of Co-g and anti-tumor substances increased the rate of tissue respiration to the control, with the exception of two cases. It seemed that the combined use of these compounds clinically produced not only good effects on the constituent factors of the blood, but also prevent liver disturbance of anti-tumor substances to some extent.抄録全体を表示PDF形式でダウンロード (392K) -
横川 礼二郎1958 年 18 巻 4 号 p. 286-292
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーIn 117 patientss who visisted our clinic, their staphylines ane intervals of palatal arch in both sides, front and rear were observed before or after tonsillectomy. The postoperative staphylines became shorter average 0.21 cm in length and longer 0.11 cm in basal wideth as compared with the preoperative. The intervals of palatal arch were all lengthened as compared with preoperation. As for difference by sex staphylines had a litte worse defoormity in females than in men, but had no difference in the intervals of palatal arch. By degrees of tonsilar hypertrophy, staphylines showed somewhat worse deformity in the moderate cases cases than in the severe or mild. As for the intervals of palatal arch, the mild cases were not so deformed as the severe or moderate. Deformities of staphylines due to tonsillectomy were divided into six classes.抄録全体を表示PDF形式でダウンロード (658K) -
横川 礼二郎1958 年 18 巻 4 号 p. 293-304
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーThe electromyographic observation was performed on fifty patients suffered from hypertrophy of palatine tonsillectomy. Treating with palatoglossus, the electromyogram showed maximal amplitude of 27 and electric discharge of 46 uv when kept quiet and 3550 cps and discharge of 46-80 uv when pronounced a vowel “A”. With palatopharyngeus it hardly or slightly discharged when kept quiet, while it showed 40-56 cps and discharge of 58120 μV when pronounced. There were encountered no difference between before and after operations. The smaller tonsills extracted showed a marked pathological change as compared with large tonsills, this having no relationship with the electromyographic result. The electromyographic relation seemed not to exist between the degree of injury of two muscles by operation and that of tonsillar hypertrophy. According to the above experiment, the electromyographic results were not affected even if the peritonsillar muscles were more or less injured macroscopically or pathologically. Thus, it would be impossible to study the influence of tonsillectomy on palatoglossus and palatopharygeus by electromyography, and to discuss articulation disorder only from the result thereofor.抄録全体を表示PDF形式でダウンロード (11189K) -
高橋 敬藏, 長沼 芳季, 金木 悟, 川崎 猛, 増川 弘1958 年 18 巻 4 号 p. 305-311
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーEffects of chlorpromazine on the liver and kidney of white leghorn embryo on the 9 th, 12 th, 15 th and 18 th day of incubation were studied histopathologically.
1) Findings in the liver
Fat appeared in intrahepato-cells abnormally, which disappeared on 18 th day of incubation. Fibrosis and cell-infiltration in Glisson's capsule were found on 15 th day of incubation and thereafter.
2) Findings in the kidney
The regressive changes of epithelium of urinary tubule were noticed.抄録全体を表示PDF形式でダウンロード (5215K) -
特に鷄胚仔肝臟に就て斎藤 隆三1958 年 18 巻 4 号 p. 312-332
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーMumpsvirus (0.2 cc), Showa B, D and Enders strain were inoculated into amniotic cavities of 7 days' hatched eggs of white leghorn.
Egg mebrane and embryo of 12 th day of incubation were embedded quickly in fixative solution for histologic and electron-optic studies.
The cases which revealed servere damage on histologic examination, showed similar findings on electroneoptic examination essentially.
Inclusion bodies and mumpsvirus were found by the electronoptic examination. The former possessed high electron density in protoplasma and nucleus of liver cell. The latter were seen in chain or scatterring arrangement along mitochondria membrane.
Through the experiment, the former conception on the degeneration of cells was discussed and more detailed results compared with the known histological changes were obtained.
In each liver cells considerable variaties of vacuolar degeneration which may called solitary vacuolar degeneration were found. These findings will be of importance for the morphologic observation of degenerative cells and of significance for the study of the mechanism of infection of mumpsvirus morphologically.抄録全体を表示PDF形式でダウンロード (14014K) -
第1報 赤血球に含まれる炭酸脱水酵素の測定に就て関根 活郎1958 年 18 巻 4 号 p. 333-336
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーConditions for the determination of carbonic anhydrase were studied. Temperature in water both was kept at 20°C and air was used as the gas phase. Enzymatic activity was calculated on the basis of CO2 production during the thirty or ninety-second period starting thirty seconds after tipping in the substrate. In the range of 1/100-1/800 dilutions of blood, there was a linear relationship between the concentration of blood and the production of CO2 for 30 to 90 sec. following the reading.抄録全体を表示PDF形式でダウンロード (469K) -
第2報 保存血液の炭酸脱水酵素について関根 活郎1958 年 18 巻 4 号 p. 337-338
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーCarbohic anhydrase activity of stored blood was studied during course of storage in the blood bank. No detectable changes of carbonic anhydrase activity were observed during 35-45 days' storage.抄録全体を表示PDF形式でダウンロード (167K) -
第3報 保存血液の赤血球滲透圧抵抗について関根 活郎1958 年 18 巻 4 号 p. 339-341
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーThe resistance of cell-membrane of erythrocytes against hypotonic salt solution was studied. Hemolysis of erythrocytes was expressed as sigmoid curve. The hemolytic curve of the professional blood donor was similar to that of the anemia. The hemolytic curve of anisocytosis was irregular and range and angle of curve were larger than that of normal. Gradual changes in curve of hemolysis were observed during storage.抄録全体を表示PDF形式でダウンロード (314K) -
第1報 保存による血漿部分の変化について篠田 謙次1958 年 18 巻 4 号 p. 342-345
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーThe change in plasma during the storage in cold was studies by paper-and Tiselius-electorophoresis. The following results were obtained.
1) In case of the storage of plasma only, no remarkable changes of lipoprotein and protein were observed.
2) In case of the blood in A.C.D solution a slight increases of α, β and γ, globulin were detected.
3) Changes of albumin, lipoprotein and globulin were discussed by means of paperelectrophoresis.抄録全体を表示PDF形式でダウンロード (415K) -
第2報 線維素分解酵素 (プラスミン) について篠田 謙次1958 年 18 巻 4 号 p. 346-349
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーMethod for determination of plasmin in blood-plasma was described previously.
Plasmin activity increased slightly during storage of blood in A. C. D. solution. There was no relationship between the concentration of plasma-protein and plasmin activity. Plasmin activity of healthy people was lower than that of professional blood-donors.抄録全体を表示PDF形式でダウンロード (365K) -
“特にNicotineの心筋に及ぼす影響について”宮川 弘久1958 年 18 巻 4 号 p. 350-366
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーThe influence of nicotine upon the heart of mouse has been studied histopathologically. One half, 1.0, 2.0, 3.0, 5.0, and 7.0 mg/kg of nicotine dissolved in either water or oil were administered to young mice subcutaneously.
Granular degeneration, vacuolar degeneration, swelling, hyaline degeneration, homogenization, histological injury, loosening of vascular wall, blown appearance and zigzagging and disappearance of argetaffine fibers of the interstitial tissue and perimysium were observed.
Hydropic changes appeared in water solution group rather frequently in cases of 0.5 and 1.0 mg/kg administration while the most in 3.0 mg/kg. In oil solution group the parallel relationship was seen between the degree of pathologic changes and the given doses.
Vacuolar degeneration, blown up appearance, histological injury, acceleration of diffusion of blood vessels in the interstitial tissue, blown up appearance, zigzagging and disappearance of argetaffine fibers of the perimysium were observed as morphologic expressien of hychopic lesions.
When the toxicity of nicotine classified histopathogenitically, granular degeneration and homogenization are considered as the secondary direct type, while the hydropic lesions of the perimysium and vacuolar degeneration, blown up appearance and histologic injury of the heart muscle fibers as the secondary indirect type.抄録全体を表示PDF形式でダウンロード (6167K) -
小沢 勝美, 杉山 心一, 近藤 富保, 谷淵 修三, 鈴木 延明, 宮下 録司, 村田 恒雄, 村田 正1958 年 18 巻 4 号 p. 367-370
発行日: 1958/07/30
公開日: 2010/11/19
ジャーナル フリー昭和32年7月25日より8月3日迄に夫々3日間ずつ某工場の高温作業場である鍛造工場, 外業及び鍍金工場, 鋳造・鋳鋼工場の3群に就て, 作業環境及び作業者の身体諸機能を調査し高温環境下の作業が生体に如何なる影響を与えているかを観察した.
(1) 温度条件を主として行った作業環境は殆んどが恕限度前後を示し, 特に鍛造工場, 鍍金工場, 鋳造・鋳鋼工場のズク熔解炉・鉋金熔解炉附近が甚しく, 黒球温度49～56.5℃, 実効輻射熱10～20℃, 気温40～47.5℃に及んでいた.
(2) 高温環境下の作業が身体の諸機能に及ぼす影響は高温と作業強度の相乗積に比例していた.即ち高温という温度条件においては3群に大した優劣はつけられないが, 作業の強度は鍛造工場が最も大で, 外業及び鍍金工場は之に次ぎ, 鋳造・鋳鋼工場が最も低かった.この状態を反映して高温作業が身体諸機能に及ぼす度合を一単的に示す示標である作業前後の体重減少度, 労働時間中の飲水量, 発汗量, 膝閾値の増加度, 全血血漿比重の増加度, 赤血球最小抵抗の減少度, 尿中食塩排泄量等は何れも鍛造工場, 外業及び鍍金工場, 鋳造・鋳鋼工場の順になっていた.
(3) 之に反して自覚症状調査を含めた疲労調査の諸成績は鋳造・鋳鋼工場が最も疲労度高く, 鍛造工場之に次ぎ, 外業及び鍍金工場が少ないのは, 作業内容から見て鋳造・鋳鋼工場が余り移動性のない作業であり, しかも勤務時間外の自由時間が著しく少ないのに反して, 外業及び鍍金工場の作業は移動性があり, 作業者の勤務時間外自由時間が大体確保されている事も原因しているものと思われる.抄録全体を表示PDF形式でダウンロード (509K) -
藤井 吉肋, 張 南薫, 西平 守正, 市原 正文, 榎本 武一, 柳沢 裕, 野口 英世, 成沢 達郎, 高島 盛輝, 山本 常市, 市原 ...1958 年 18 巻 4 号 p. 371-375
発行日: 1958/07/30
公開日: 2010/09/09
ジャーナル フリーPDF形式でダウンロード (759K)
- |<
- <
- 1
- >
- >|