昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
21 巻, 1 号
選択された号の論文の9件中1~9を表示しています
  • 追川 実男
    1961 年 21 巻 1 号 p. 1-9
    発行日: 1961/04/28
    公開日: 2010/11/19
    ジャーナル フリー
    To clearify the relation between the changes of serum protein component and the production of antibody in the schistosomiasis the author studied experimentally on the changes of serum protein components of mice and the precipitin reaction which conducted with 3 agents prepared from adult worms cercariae and eggs in mice and rabbit with schistosomiasis. The changes in serum protein component were investigated by the paper-electrophoresis.
    Experimental results were as follows:
    1) . Total protein was increased after 3 weeks and reached the maximam after 9 weeks after the primary infection and showed further increase after the superinfection.
    2) . Decrease in albumin was recognized in 5 weeks but 8.9 weeks later it recovered to the normal. The albumin of mice superrinfected after 2-3 weeks after the primary infection showed a decrease less than that of the control, but when the superinfection . was performed after 4-7 weeks after the primary infection albumin showed an increase when compared with that of the control.
    3) . Increase in α-globulin was recognized in 5 weeks and it reached the maximum in 9 weeks, and after snperinfection the changes of a-globulin wre scearcely found.
    4) . The increase in β-globulin was recognized in 5 weeks and reached the maximum in 6 weeks after primary infection and after the superinfection the changes of β-globulin depend upon the number of worms.
    5) . The remarkable increase in γ-glnbuln was recognized in 6 weeks and reaceing the maximum in 7 weeks. After the superinfection the changes of γ-globulin depends upon the number of the infected worms.
    6) . The remarkable decrease in A/G ratio was observed in 5 weeks and reaching the maximum in 6 weeks after the primary infection. After the superinfection the changes of A/G ratio was scarcely found.
    The result of the precipition test conducted with 3 kind of antigens was as follows.
    1) . Worm antigen gave a positive result 2-3 weeks infection.
    2) . Cercarial antigen showed positive result in mise and rabbits in 3 weeks after the primary infection.
    3) . Egg antigen gave a positive results in mice and rabbits in 5 weeks infection.
    It is considered that the decrease of albumin has no correlation with precipitin reacrion when those 3 antigens were used. The increase of α-globulin has correlation with precipitin reaction conducted with the use of worm and cercarial antigens. When egg antigen was used the increase of β-globulin has correlation with precipitin reaction and the increase of γ-globulin has correlation with precipitin reaction when those 3 antigens are used.
  • 追川 実男
    1961 年 21 巻 1 号 p. 10-15
    発行日: 1961/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    The author reported a case of suppurative meningitis which complicated with the cholesteatom otitis. From the clinical and operative views, the pathogeny of this case is considered that the meningeal extension of the inflammation seemed to be occurred from the brain-abscess near the left ventricle which occurred from the inflammation of middle ear, along by the sorrounding tissues of the 2nd branch of Durets vessel.
  • 追川 実男
    1961 年 21 巻 1 号 p. 16-18
    発行日: 1961/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    Patient is a man, aged 49 years, was seemed to be suffered from the chronic suppurative cholecystitis at the early stage. Bacteriological examination clarified that the pathogenesis of this case is a parasite of the lamblia on the gall-bladder.
  • 趙 雲夏
    1961 年 21 巻 1 号 p. 19-52
    発行日: 1961/04/28
    公開日: 2010/11/19
    ジャーナル フリー
    With an intention of claritying the decomposing mechanism of the kidney of homologous transplantation, experiments of the homologous kidney transpaantation were undertaken together with double homologous transplantation by the use of Cortison. The results obtained were as follows:
    1. The kidney of homologous transplantation starts the excretion of urine within 24-48 hours. This urine is normal except its lower specific gravity and acidity. When the transplanted kidney begins to decompose, the urinary quantity reduces followed by the appearance of acute anuria syndrom When the host possessed only the transplanted kidney, the residual N content of the blood showed an increase causing uremia.
    2. The transplanted kidney was enlarged by the post-operative thickening of the capsule. Histologically, there was a marked infiltration of pyroninophilic round cells in the cortex and the decomposition of the parenchyma of transplanted kidney was observed only in the cortex.
    3. Of the main visceral organs of the recipient, marked infiltration of pyroninophilic round cells was observed in the liver, lung, pancreas and the spleen.
    4. Mean survival period of the transplanted homologous kidney was 6 days.
    5. Acut anuria syndrom observed on the cases possessed the residual kidney are considered as a temporarily immunological phenomenon caused by the damage of the residual kidney.
    6. Significance of the appearance of round cells following the homologous kidney transplantation is not clear, but it can be considered that they are produced in the reticuloendothelial system of the trans planted kidney by the antigen-antibody reaction of the heterologous protein between the transplanted kidney and the reipient and, moreover, they participate in the antibody production on the transplanted kidney itself.
    7. In the experiment of the double homologous kidney transplantation made by the use of Cortison, urinary excretion begins earlier in contrast to the group without Cortison. Decrease in the urinary amount which follows the decomposition of transplanted kidney is slow and the appearance of acute anuria syndrom as well as the symptoms of uremia are remarkably alleviated.
    8. The transpranted kidney shows a marked enlargement, but the renal capsule shows no thickening. As for for histological changes, they are mostly the same as the findings of the kidney of homologous transplantation.
    9. Of the findings of main visceral organs, the presence of pyroninophilic round cell infiltration in the kidney of the secondary transplantation was the same as in the case of the homologous transplantation, but the cellular infiltration was absent in the other organs.
    10. Survival period of the transplanted kidney showed no appreciable difference from the group did not receive Cortison.
    11. In the experiment of double homologous kidney transplantation, clinical and histological findings appear to show a considerable effect of Cortison administration, but there are also some doubtful points.
    12. In view of the histological findings of the two experiments stated above, it is considered that a kind of organ specific immunological reactions participate in the immunological reactions between the transplanted kidney and the recipient.
  • 趙 雲夏
    1961 年 21 巻 1 号 p. 53-55
    発行日: 1961/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    Frequency of the appearance of lymphosarcoma formed in the digestive system is said to be high in the order of the stomach, duodenum, ileum and the jejunum. Jejunal lymphosarcoma was found on a male of 28 years old. Descriptions were made on its roentgenological and histopathological findings with considerations on the literature.
  • 谷 鋭三郎
    1961 年 21 巻 1 号 p. 56-63
    発行日: 1961/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    TO make an inference of the postmortem duration is as important as the diffetential diagnosis of death whether by drowing or by other causer. This inference, however, is highly difficult.
    Text books on legal medicine and literatures hitherto published fail to give precise informations as to how long does it take before a drowned corpse start bloatiug up on the surface of water. In this connection, an investigation was made on the drowned corpses in Tokyo in the past 10 years with known date and time of death and the exact locality of appearance dy floating up. Results obtained are believed to be of some practical value in the field of legal medicine. Their reliability, further, was conrfirmed by animal experiments.
    1. Average days spent before drowned corpses float up by the generation of putrid gas in the rivers and in the vicinity of harbours in Tokyo (depth1.5-7.0) were markedly varyant depending on the season of the year being 1.8 days in August and 28. days in January, namely, they are closely related with the temperature of water.
    2. Both the specific gravity of water and the intensity of contamination are larger in the lower stream of a river. if those two factors have some association with the floating up of drowned corpses, the days required must be longer in the upper stream than those in the lower stream, but in fact no such difference was recognizable between them.
    3. Mean surface water temperatures of the rivers and harbours in Tokyo were determined in each month and they were tabulated with the respective findings of the days required for floating up of corpses determined by statistic calculation. Thus, a table for the inference of the days required for floating up of corpses was prepared by the difference or season or water temperature.
    4. Based on the findings of animal experiments, it is concluded that the reduce in the specific gravity of corpses by the generation of putrid gas takes place rather quickly after a certain lag period which is dependent mostly on the temperature of water and that it does not show a gradual increase following the lapse of time time. Accordingly, the difference in the specific gravity at the time of drowing is considered to have little influence on the duraton of the days required for floating up.
    5. Relationship of the water temperature and the days required for floating up of corpses observed on animal experiments confirmed the reliability of the aforementioned table prepared for the inference of the days required for floating up of corpses by the difference of season or water emperature.
  • 脇阪 一郎, 伊東 享, 木村 誠之, 山口 直
    1961 年 21 巻 1 号 p. 64-67
    発行日: 1961/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    115 lead workers medically noticed in 600 subjects. These workers were statistically investigated, and the following results were obtained.
    1) . Anemia were in 52 subjects, urinary coproporphyrin were in 66 subjects and stippled cells were in 31 subjects respectively observed. Most of these subjects have a simple symptom.
    2) . Anemia and coproporphyrinuria were observed in the young or inexperienced person, but anemia and stippled cells were observed, in old or skilled operatives.
    3) . When the symptom was simple, it was relatively clear.
    4) . The lead level in blood has norelation with anemia nor coproporphyrinuria, but it has a little relation with stippled cell counts.
  • 脇阪 一郎, 山口 直, 井上 房江
    1961 年 21 巻 1 号 p. 68-72
    発行日: 1961/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    418 workers who were exposed to noisy environment in industry were examined by an usual audiometer. The following results were obtained.
    1) There are pretty many middle-aged person in industry workers who were exposed to noisy environment.
    2) The most of test ears showed the hearing loss from 5 to 25 db, but about a tenth of these showed the hearing loss above 30 db.
    3) The difference of about 5 db was observed between the hearing loss of boss test ears, and its standard deviation was 8. 16db.
    4) The appearance of the subjects whose hearing loss were above 30 db increased due to working years above 10 years.
    5) The hearing loss in the high frequency range was appeared in the early stage of working years, and the one in the low frequency range was appeared in the late stage.
  • 杉山 規矩夫, 外山 順一, 林 正, 玉城 清栄, 神田 実喜男, 浅沼 勝美, 高木 辰男, 笠原 照邦, 識口 都三, 橘 浩司, 吉 ...
    1961 年 21 巻 1 号 p. 73-76
    発行日: 1961/04/28
    公開日: 2010/09/09
    ジャーナル フリー
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