昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
38 巻, 2 号
選択された号の論文の12件中1~12を表示しています
  • 198Au組織内照射および速中性子線照射―
    調所 廣之
    1978 年 38 巻 2 号 p. 129-135
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
  • 藤田 力也, 佐竹 儀治, 川瀬 定夫, 大栗 茂芳, 小林 明文, 遠山 啓一郎, 倉俣 英夫, 菅田 文夫, 田崎 博之, 小町谷 琢也 ...
    1978 年 38 巻 2 号 p. 137-143
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    We have carried out 2371 examinations of digestive endoscopy during one year, from January 1976 at SHOWA UNIVERSITY, FUJIGAOKA HOSPITAL.
    Digestive endoscopy which includes diagnosis and treatment of all gastrointestinal tract, pancreato-biliary tract, was applied in a frequency of 1, 44% for the whole patients with increasing indications.
    Early gastric carcinoma was practically detected in 10 cases (37%) out of 27 resected gastric carcinoma. Regarding to malignancy detection, confirmation was made as follows ; esophageal carcinoma 13, gastric carcinoma 89, gall blader carcinoma 3, liver tumor 2, pancreatic carcioma 2 and colonic carcinoma 11,
    Attractive endoscopic surgery has been in practice, in which polypectomy, papillotomy and resection of sub-mucosal tumor of the stomach were easily performed without severe complications.
    Proposal of supervision and follow-up study is extremely valuable as well as an endoscopic technique, which has been completed by the aid of office-workers.
    Further development of digestive endoscopy will be accomplished by the efforts of young persons to change old impossibility to new possibility.
  • ―とくに, 結婚, 職業について―
    明樂 進
    1978 年 38 巻 2 号 p. 145-163
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    Of the epileptics, their social lives, especially their nuptial and occupational circumstances were studied. Many of the past studies upon them were concluded with disadvantageous results against them, but the author analyzed and examined the real data collected doubting their such conclusions mentioned above, wondering whether they were still valid.
    Out of 234 epileptic outpatients who had already attended the neuropsychiatric clinic of the Hospital of Showa University for longer than 5 years before March 1974, but both 19 who had visited very irregularly and 6 whose histories showed obvious headtrauma or encephalitis were excluded, and so residual 209 were actually studied.
    Of social and medical inquiry items already made, answers were obtained from the applicable patients and their families, which were statistically analized and examined employing T-test, F-test, Chi-square, Variance, Correlation etc. And the following results were obtained.
    (1) Average nuptial age is later than Nationalaverage by approxymately 2 years, which makes no significant difference.
    (2) There is significant positive correlation between nuptial age and that of seizure onset in feminine premarital onset group, but no significant correlation between male and female concerning postmarital onset group.
    (3) Nuptial life seems not to provocate any changes of clinical types of seizure (with or without convulsion, and day or night type) .
    (4) Those epileptics hereditary imposed within the 2nd degree seem to get earlier onset age than non-imposed by approxymately 2 years, but there is no significant difference between them.
    (5) There is no deviation of occupational choice in those with onset before employment, and also the kind of occupation seems not to provocate epileptic onset. Therefore, reconsideration seems necessary for the advices of the occupational choice of the epileptics given hitherto.
    (6) It seems that there is no specific correlation between the types of clinical seizure and the kind of occupation.
    (7) Many of the past studies on the epileptics so far made conclusions agaist them, employing simple arithmetical method or simple percentage, and they emphasize the peculiarities of the epileptics whereby.
    But there seems that no such peculiarities of their's exist by means of statistic analyses.
    This fact is considered to make a contribution toward epileptics and their families so as to diminish their anxieties and fears due to epileptic disorder.
  • 川瀬 定夫, 菅田 文夫
    1978 年 38 巻 2 号 p. 165-177
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    Experiments were performed to assess chenodeoxycholic acid (CDCA) and ursodeoxycholic acid (UDCA) as to litholytic efficacy for biliary cholesterol gallstones, with the results as follows.
    1. Groups of squirrel monkeys which had been maintained on a cholesterol-rich diet for twelve months were fed rations containing CDCA or UDCA over periods of 6 to 12 months, and compared to an untreated control group in respect of bladder bile composition, liver function and light and electron microscopic features of the liver tissue.
    There was a conspicuous decrease in cholic acid (CA) content in bladder bile composition of CDCA-dosed animals as compared with animals given UDCA, and the bile from the CDCA-treated group showed a slightly higher content of lithocholic acid (LCA) whereas the UDCA-treated group virtually did not differ from the control group. Biochemical analysis of the liver function also revealed slightly abnormal values in the CDCA-treated group in which light microscopic evidence of modest cholestasis and pronounced electron opacities of hepatocytic mitochondria were observed. These findings seem to indicate that CDCA possesses a slightly greater hepatotoxic potential than UDCA in squirrel monkeys.
    2. No significant differences were noted to exist in the composition of human bladder bile, drawn from the duodenum, among the three groups : cholesterol cholelithiasis, noncholesterol cholelithiasis and without cholelithiasis. It would follow that it is not always advisable to determine the indication for the use of litholytic medication solely on the basis of chemical analytic findings for the bile.
    3. The effects of orally administrated CDCA and UDCA on the hepatic bile composition were investigated by way of collecting specimens via a T-tube from post-cholecystectomy patients. Both drugs caused decrease of cholesterol content in the percentage composition of hepatic bile whilst the lecithin content remaind essentially unchanged. The results may indicate that the decrease in biliary lithogenic index (L.I.) following administration of CDCA or UDCA is effected through the mechanism whereby the compounds suppress cholesterol excretion into the bile.
    The data suggest the possibility that both CDCA and UDCA have litholytic activity for cholesterol stones, the efficacy being more conspicuous with UDCA as estimated from the findings in squirrel monkeys.
  • 宗近 宏次, 岩崎 統, 古賀 靖, 馬場 博康, 高橋 久男, 飯野 史郎
    1978 年 38 巻 2 号 p. 179-185
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    If there is strong clinical and laboratory evidence to suggest the presence of adrenal pathology, the presence or absence of and localization of the abnormality should be demonstrated radiologically for surgery.
    We recently had three cases of adrenal adenomas, two cases of Cushing's syndrome and one case of primary hyperaldosteronism. The evaluation of the radiological approach to adrenal adenomas was discussed in these cases.
    In relatively large adrenal adenomas, localization of the adenoma can be relatively easily recognized radiologically. It is emphasized that adrenal scintiphotogram by NCL-6-131I is not only non-invasive but also is usuful study to detect adrenal adenomas.
    If the scintiphotogram is equivocal because of being small, selective adrenal venography with blood sampling from the adrenal vein for hormone assay would be of value.
  • 渡辺 浩之
    1978 年 38 巻 2 号 p. 187-196
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    The 38 autopsy cases of primary carcinoma of the pancreas, containing 9 cases performed Pancreozymin-Secretin Test (P-S test) were studied pathologically in order to make clear relation between the values of P-S test and morphology of pancreatic carcinoma. Experimental carcinogenesis of the pancreas were attempted in rats after the implantation of 7, 12-dimethylbenz (a) anthracene (DMBA) to examine histogenesis of carcinoma.
    The 67 per cent of pancratic carcinoma performed P-S test revealed abnormal values : A decreased tendency of each parameter of P-S test was apt to be shown in cases of diffuse invasion to the pancreas and with much stroma of carcinoma. The volume of pancreatic juice was not often influenced by carcinoma. And no significant relation was showed between occupational region of carcinoma and extent of decrease values of P-S test.
    The 24 per cent of 29 rats induced malignant tumor of the pancreas ; 5 well different adenocarcinomas, one spindle cell sarcoma and mixed tumor of adenocarcinoma and spindle cell sarcoma. Spindle cell sarcoma was thought myosarcoma after light and electron microscopical examination. Adenomatous hyperplasia was observed in all cases except one.
  • 猪口 清一郎, 後藤 勇, 木村 忠直, 野井 信男, 朴 恩〓, 岩本 壮太郎, 南雲 祐司, 佐藤 亨
    1978 年 38 巻 2 号 p. 197-211
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    The thickness of the hypodermic fatty layer was measured on 183 subjects of junior high school boys and girls in Tokyo. The measurement was taken from 36 different points of the body and the interrelationship between the thickness and the body type was examined. Body type was divided into 4 groups ; thin, standard, fatty and very fatty.
    1. The thickness of the hypodermic adipose tissue was thicker in order of body types from very fatty to thin, but was seen few difference between the thin type and the standard type on boys.
    2. The increasing rate of the thickness of hypodermic fatty layer in 4 body types was remarkable on the circumference of navel by standard type, on the anterior part of trunk, proximal anterior part of upper extremity and upper posterior part of trunk by fatty type, and on the breast, anterior part of trunk and proximal part of upper extremity by very fatty type respectively on boys. On the other hand, it of girl was remarkable on the thinner part of hypodermic fatty layer in body and was remarkable around the hip by very fatty type.
    3. The distribution of the subcutaneous adipose tissue on the very fatty type was remarkable on the upper half of body by boy and on the lower half of body by girl respectively.
    4. Concerning the hypodermic adipose tissue of junior high school boys and girls in Tokyo, it can be said that the distribution pattern, sex-difference and age-related changes are resemble to them in other district of Japan but the thickness is larger than its in Okinawa.
    5. From the thickness of the hypodermic fatty layer, thin type was equivalent to those of below 119 of Rohrer's index on both sexes, standard type to 120-139 on boys and to 120-129 on girls, fatty type to 140-149 on boys and to 130-149 on girls, and very fatty type to more than 150 on both sexes.
  • 松本 治雄, 菅原 広一, 岡崎 恵子
    1978 年 38 巻 2 号 p. 213-218
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    The process of speech acquisition of a speechless child was observed.
    The child was two year and eight month old boy who had been speechless, except for snatcy utterances in inhaling breath. There was no problem in understanding, intelligence, and the over-all behavior.
    Speech therapy to the child and educational guidance to the child's mother were given once a week for ten months. In direct speech therapy, to improve speech breathing pattern, blowing, C.S.S., and gargling exercises were introduced, and to elicit articulation, “onomatopoeis”was utilized. Indirectly, the mother was instructed to do homeworks with the child everyday, and to establish a desirable environment for the child.
    After improvement of speech breathing pattern, the child acquired speech sounds rapidly. The order of acquisition was almost the same as that of normal children.
    The child's utterance pattern was analyzed by soundspectrograph. It proved that the child's utterance pattern was similar to one of the patterns in babbling.
    It is considered that the child's abnormal speech breathing pattern had worked as an inhibitor, and when it was removed, the child started to move on to the normal speech development.
  • 奥山 雄一, 井上 梅樹, 浅野 洋治, 水上 忠弘, 布上 直和, 友安 茂, 北村 公博, 森川 昭洋, 村田 正, 糸川 正, 増山 ...
    1978 年 38 巻 2 号 p. 219-224
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    A 45 year-old man was admitted to our hospital becasue of headache and fatigue. On admission, blood pressure was 260/150 mmHg The heart was definite left ventricular hypertrophy.
    The retinal changes was Keith Wagener III ; the renal function was slightly disturbed and plasma renin activity was 2.3 ng/ml/hour. On 104th hospital day, he died of cerebral haemorrhage and perforation of duodenal ulcer.
    Histological findings showed fibrinoid necrosis of affrent arteriole and a part or complete necrosis of glomerulus. Duodenum showed perforation of little finger's head sized ulcer with infiltration of inflammatory cell and proliferation of fibrous connective tissues histologically.
    The brain was 1340 g in weight and showed thumb's head sized hemorrhages in the area of left lenticular nucleus without fibrinoid changes of blood-vesseles.
    Fibrinoid necrosis of arterioles was noticed in adrenocortex, periadrenal tissues and pancreatic parenchyma and environs. This patient died with haemorrhage of cerebral and perforation of duodenal ulcer on the state of premalignant phase.
  • 渡辺 悟郎, 中島 仁, 米山 正美, 窪田 哲昭, 赤池 清美
    1978 年 38 巻 2 号 p. 225-227
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    A case of blood boil was reported, and additional information abtained from the literature was presented. This case was suspected maligmant tumor of maxillary sinus according to clinical history and examination finding, but was histologically cavernous angioma.
  • 永納 和子, 庭野 信子, 安本 和正, 松崎 史朗
    1978 年 38 巻 2 号 p. 229-233
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
    Eight cases of bilateral parotid gland swelling were observed during and after endotracheal anesthesia.
    The patients were 3 males and 5 females and their ages ranged from 48 to 75 years, with an average of 62.6 years of age.
    In the most of the cases swellings were found immediately after extubation.
    These swellings disappeared without any paticular treatment within the third day, except one case in which the swelling remained for more than a month.
    In this series the incidence of parotid gland swelling was eight in 927 endotracheal anesthesia, being approximately 0.86 percent of the total cases.
    Parotid gland swelling occurs at a higher rate more than expected.
  • 上里 忠正, 小出 良平, 小口 勝司, 小林 真一, 庄 貞行, 柏山 基子, 平井 和子, 平沢 政人, 千住 紀, 細谷 純一郎, 五 ...
    1978 年 38 巻 2 号 p. 235-240
    発行日: 1978/04/28
    公開日: 2010/09/09
    ジャーナル フリー
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