昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
19 巻, 4 号
選択された号の論文の12件中1~12を表示しています
  • 高塩 昭三, 永根 純一, 糸川 正, 加藤 憲三, 田代 浩二, 田中 利明, 久保田 健
    1959 年 19 巻 4 号 p. 285-290
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    An autopsy case report of duodenal cancer originated from pars descendens is: presented. This patient was diagnosed as carcinomatous peritonitis and not clinically examined to find primary focus because of severity of illness.
  • 丸山 海〓, 高塩 悌二
    1959 年 19 巻 4 号 p. 291-299
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    A total of 31 patients received ambulatory or “open ward” treatment with Triominn alone, or in combination with Chlorpromazine, Cafilon or with a kind of psychotonics suchh as electro-convulsive therapy.
    Complete remission or remarkable improvement was seen in 28 cases, but there were 3 cases which did not respond favourably.
    The dosage of Triomin used was 1/6-1/5 of Chlorpromazine.
    Triomin was effective on the patients who had failed to respond Chlorpromazine: treatment.
    Combined medication of Triomin with Chlorpromazine or with a stimulant of thee central nervous system such as Cafilon was, in some cases, more effective than using themm alone separately.
    Triomin was found to improve markedly the psychomotor excitement, depressivee state with agitation, anxiety, hallucination and delusion.
    Triomin increased the spontaneity of the patient and never decreased it as did Chlorpromazine. It, however, did not have euphoric effect.
    Parkinsonism was observed often as a side reaction in the treatment with this, drug. This side reaction, however, seemed to be rather favorable from the therapeuticc point of view. Serious side reactions such as the disturbance of liver function or drug; eruption etc were not observed.
    This drug was not always a satisfactory substitute for schock therapy, especially electro-convulsive therapy. By using this drug, however, relatively heavy psychotics can, be easily and safely treated with a rapid cure as out-patient or in open wards.
  • 神田 実喜男, 李 相均, 林 茂, 北浦 賢, 芝木 武雄, 佐藤 忠邦, 高松 保, 大内 繁
    1959 年 19 巻 4 号 p. 300-303
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    1. A report was made on a case of catatonia, female, 20 years old, who died probably of Chlorpromazin intoxication developing shock by the administration of 200 mg Chlorpromazin (a daily dose of 100 mg for 2 days) .
    2. Side reactions of the circulatory system, central nervous system and respiratory system were observed at the time of shock, especially tachycardia, coma and dyspnea were marked.
    3. As for patho-histological findings, the liver presented a degenerative picture suggestive of chemical intoxication characterized by general edema with the deposition of fibrinoid substance.
    4. In the brain, the aggravation of the changes like degeneration, of nerve cells hydropic loosening, migration of erythrocytes etc, in an advancing order from the end-brain to mid-brain and then to the medulla suggests their close association with the causes of death, especially dyspnea and circulatory disturbance.
  • 久保田 健, 田中 利明, 杉村 武久, 水谷 薫, 浮島 成一, 佐々木 真爾, 坂本 和夫, 佐川 文明, 田代 浩二, 平福 一郎
    1959 年 19 巻 4 号 p. 304-308
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    Since the establishment of the Second Department of Pathology in Showa Medical School in 1953, there have been 331 autopsy cases. Nearly half of those cases were of malignant neoplasm. Several statistical data were presented. Evidences were given as to the steady increase in the number and the percentage of autopsy cases.
  • 小松崎 茂, 谷 鋭三郎, 邱 松英, 張 金清, 呉 槐燦, 柯 財
    1959 年 19 巻 4 号 p. 309-311
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    1. Findings of the authors experiments show that each of the 3 syphilitic reactions, Murata's, Ogata's and glass plate methods, possess a certain portion of non-syphilitic reaction, in other words, these reactions are not of completely specifici.
    2. Specificity of each reaction on the positive sera examined by the difference of blood group was in the order listed below:
    Murata's reaction A>O=B=AB
    Ogata's reaction O>B>A> B
    Glass plate method O>A>B>AB
  • 金木 悟, 稲田 謙三, 小林 五郎, 大野 昭二, 山崎 雅治, 大月 一司
    1959 年 19 巻 4 号 p. 312-319
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    Perfusion experiments on the hind leg vessels of the toad were carried out under urethane anesthesia.
    The vasodilatory effect of arsenic trioxide was inhibited by the simultaneous administration of glutathione and cysteine, while it was not in the case of using oxidized glutathione or cystine. From this fact SH radical is conjectured to play a important role in the inhibition.
    When the time elapsed f olowing mixture of glutathione with As, the inhibitory effect of glutathione became reduced.
    Mercaptide formation between As and G-SH or Cy-SH was not demonstrable by iodine titration method.
  • 第1報 嗅覚計並に正常者の嗅覚に就て
    宮尾 赳
    1959 年 19 巻 4 号 p. 320-329
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    1. Literatures related with olfactometer were surveyed.
    2. A special olfactometer was devised taking into consideration various conditions especially pressure, velocity, temperature, moisture and diffusion.
    3. Normal minimal identifiable odor was designated by pressure.
    4. Olfactographs were drawn.
  • 第2報病的者の嗅覚について
    宮尾 赳
    1959 年 19 巻 4 号 p. 330-344
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    1. Minimal identifiable odor (MIO) was surveyed and olfactograms were drawn for 37 cases with nasal disorders. Individuals without nasal disorders show olfactograms of straight horizontal lines, while those with nasal disorders show varying lines which can be divided into. four types. According to the studies, significant correlations were found to exist between the olfactogram and intranasal construction.
    2. MIO and olfactogram were in proportion to the intensity of nasal signes, nasal disorders and objective olfactory sense.
    3. Statistic observations with to the intranasal construction, nasal signes and nasal disorders were performed on the 21 cases with so-called anosmy for which olfactometry was not applicable.
    4. MIO was determined on the 3 cases of chronic sinusitis and on the 3 cases of tonsillitis prior to and after operation, and this method was proved to be benecial for the observation of the effectiveness of operations on olfactory sense.
  • 広瀬 建市
    1959 年 19 巻 4 号 p. 345-365
    発行日: 1959/06/30
    公開日: 2010/11/19
    ジャーナル フリー
    Chick Embryos received the injection of Atophan and the results obtained were as follows:
    1. Weight of the embryos showed no significant difference from the control when the concentration of Atophan was low, while when it was high the weight was reduced and all embryos died in the latter half of their hatching period.
    2. Concentration of uric acid in the allantoic fluid increased following the advance in the days of embryonation and was high on the embryos received Atophan injection of low concentration than those received high concentration.
    Total uric acid content was highest on the 15 th day of embryonation. The uric acid content, moreover, was found to be remarkably increased in spring than in winter.
    3. On histological investigation made on the liver and the kidney, moderate retrogressive degeneration was recognized irrespective of the period of embryonation.
  • 榎本 幸彦, 稲田 謙三, 本西 キミコ, 金 正沢, 長田 徹, 小林 五郎
    1959 年 19 巻 4 号 p. 366-371
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    Stated in the following are the results obtained from the investigation made on the pharmacological activities of thiamine tetrahydrofurfuryl disulfide (TTFD) .
    1. Mouse LD50 of TTFD was 800 mg/kg by the subcutaneous injection made on the dorsal portion.
    2. Rabbits received an intravenous injection of TTFD under urethane anesthesia showed increase of the blood pressure as well as excited respiration.
    3. TTFD showed an inhibitory action on the isolated heart of rabbit and toad and caused dilatation of the coronary and ear-lobe blood vessels. It showed no effect, however, on the hind leg vessels of the toad.
    4. Pendular movement of the extirpated intestine of rabbit was inhibited by TTFD. Movement of the isolated uterus of rabbit was reduced, but its tension was enhanced.
    5. In view of the findings of the respiratory and circulatory systems of rabbit andd toad, TTFD was found to show no appreciable influence on the effect of adrenaline.
  • 村井 敬爾
    1959 年 19 巻 4 号 p. 372-383
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
    1. Rabbits received subcutaneous injections of Parathion in a dose of 2, 4, 8 or 12 mg/kg and pathohistological investigations of the heart were made dividing the animal into fatal groups of acute, subacute and chronic and those survived for a relatively long period of time (120-200 days) .
    2. The basic tissue destructive lesions observed on myocardium were the hydroma formed among muscle fibers characterized by the instainability of capillary PAS, and vacuolar degeneration of the adjacent muscle fibers.
    3. As for the basic lesions of the coarse interstitium, endothelial swelling and loosening or hydropic swelling of the vascular muscle layer were observed with cicatrization occasionally accompanying collagenization following the elapse of time.
    4. Hydroma formed among muscle fibers gradually showed oligocellular reticulin fiber production and occasionally there was a tendency to collagenization. Scars formed on the coarse interstitium were always connected, at least, among the fatal cases.
    5. Rabbits died acute or sub-acute death showed the development of fatty degeneration of myocardium in the lesions where both inter-musclefiber hydroma and vacuolar degeneration were present. While, rabbits died of chronic death or those survived showed gradual appearance of diffusive fatty degeneration in compliance with the diffusive intermusciefiber fibrosis.
    6. Inter-musclefiber fibrosis was the main lesion of the survived group suggesting that the space between muscle fibers is more susceptible than the coarse interstitium.
    7. In view of the changes observed on the myocardium, Parathion intoxication is considered to be a kind of the diseases of the disturbance of tissue oxydation-reduction enzymatic system.
    8. The interstitial fibe fibrosis of myocardium described above is considered to have resulted from the administration of Parathion first by hypoxydose causing hydroma and then its hardening.
  • 大津留 敬, 黄 伝福, 入江 正美, 志田 正, 鈴木 快輔, 鈴木 茂能, 岩堀 二郎, 新谷 博一, 西野入 尚一, 成沢 達郎, 井 ...
    1959 年 19 巻 4 号 p. 384-386
    発行日: 1959/06/30
    公開日: 2010/09/09
    ジャーナル フリー
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