Dietary intakes of chlordane (CHL) were investigated in order to clarify the degree of contribution of the routes of human exposure. Seventy-five daily diet samples from 25 housewives living in the Kinki area and 25 samples from 25 housewives living in Ebetsu City, Hokkaido, were analyzed for CHL complex (6 compounds) and 4 other organochlorine compounds. Mean intake of CHL in the Kinki area, approximately 2μg/day, was higher than those of DDT, DDE and HCB. Intakes of all of the CHL complex in the Kinki area were significantly higher than those in Ebetsu, though other organochlorines were in the same ranges. Close and statistically significant relationships between dietary intakes of chemicals and fishes were observed for all of the pollutants analyzed in non-CHL-treated homes, confirming the results reported by others. In the CHL-treated homes, however, intake of CHL complex were not related to the amount of fish intake even though intakes of DDT, DDE and HCB were, again, related to that of fishes. The significance of the differences of chemical intakes between CHL-treated and non-treated homes was examined by using student's
t test. No significant change was observed for DDT, DDE, HCB or HCE between these 2 groups. Intakes of CHL complex for treated homes were, however, remarkably higher than those of non-treated homes. Moreover, the chromatographic patterns of CHL complex in the diet from treated homes were very specific, indicating that relatively volatile components in technical CHL might be absorbed by certain foodstuffs. These results show that human exposure to CHL in nontreated homes depends mainly on the intakes of fishes, similar to the exposure to PCB and DDT. On the other hand, in a CHL-treated homes, participation of some other route, which could be a major source of human exposure, was indicated.
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