巻号一覧
65 巻, 4 号
選択された号の論文の6件中1～6を表示しています
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年間特集「超」：ノート
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芳川 満輝, 内田 亮, 黒木 巽, 三熊 敏靖, 蛭田 勇樹, 永田 佳子, 金澤 秀子原稿種別: 年間特集「超」：ノート
2016 年 65 巻 4 号 p. 173-179
発行日: 2016/04/05
公開日: 2016/05/10
ジャーナル フリーRecently, the need for the analysis of psychotropic drugs has increased. With the revision of the medical treatment fees in FY2014, facilities that can be calculated in those case that could identify the drugs responsible for acute drug poisoning of a patient by instrumental analysis, including HPLC analysis, were expanded from only advanced emergency medical care centers (30 facilities nationwide) to emergency medical care centers (263 facilities nationwide). Since the responsible drugs can include barbiturate drugs used as antiepileptics and tricyclic drugs used as antidepressants, methods to analyze psychotropic drugs are needed. Moreover, in emergency medicine, it is necessary to quickly identify the cause of acute drug poisoning. Ultra-high-speed HPLC has become increasingly popular in analytical research fields. In this study, we investigated the analysis of psychotropic drugs using an ultra-high-speed HPLC system. The HPLC utilized in this study was a ChromasterUltra Rs system (Hitachi, Tokyo, Japan) equipped with a photodiode array detector. Using a LaChrom Ultra C18 column (particle size; 1.9 μm) as the analytical column, rapid and simultaneous analysis of 14 psychotropic drugs (five barbiturates, three benzodiazepines, five tri- and tetracyclic antidepressants, and trazodone) was achieved within 5 min.抄録全体を表示PDF形式でダウンロード (1087K)
総合論文
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垣内 隆, 山本 雅博原稿種別: 総合論文
2016 年 65 巻 4 号 p. 181-191
発行日: 2016/04/05
公開日: 2016/05/10
ジャーナル フリー適度な疎水性を持つイオン液体を塩橋に使用すると，濃厚KCl水溶液からなる塩橋では不可能であった低イオン強度水溶液のpHを正確に測定することができる．また，試料水溶液が疎水性イオンを含まなければ，pH標準緩衝液より高いイオン強度を持つ試料のpH測定にも，イオン液体塩橋は有望である．イオン液体塩橋は，水素イオンのみならずその他のイオンの単独イオン活量測定を広いイオン強度範囲で測定することを可能にするので，pH測定の実用的な観点のみならず，長年にわたる濃厚KCl水溶液塩橋を用いるポテンショメトリーの枠組みを越えた電解質溶液の研究が展望できる．抄録全体を表示PDF形式でダウンロード (826K)
報文
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親松 和紘, 青木 元秀, 内田 達也, 梅村 知也, 熊田 英峰原稿種別: 報文
2016 年 65 巻 4 号 p. 193-201
発行日: 2016/04/05
公開日: 2016/05/10
ジャーナル フリー加圧溶媒抽出（PSE）法を用いて道路面堆積粉塵（路上粉塵）から多環芳香族炭化水素（PAHs）を抽出するための抽出溶媒を検討した．既報や公定法で多用されるトルエンとジクロロメタンをベースとなる抽出溶媒とし，補助溶媒としてメタノールの添加割合を0～50％ の範囲で変えて抽出を行い，PAHsをガスクロマトグラフィー─質量分析法（GC-MS）で測定した．測定結果の比較から，トルエン100％ のときにPAHsの抽出効率が最大で，夾 雑物の混入量を最も低く抑えられることが分かった．既報で報告された補助溶媒の添加による抽出効率の向上は認められなかった．ジクロロメタンでもメタノール添加なしの場合に最良の結果を与えたが，トルエンと比較して高分子量のPAHsの測定値が低くなる傾向が認められた．抽出に用いるベース溶媒によって僅かながら複数のPAHsの異性体比に差が認められた．PAHs異性体比は起源識別や動態解析の有力な指標として利用されるが，本研究の結果から，抽出条件によって異性体比が変化する可能性を考慮する必要があることが示された．抄録全体を表示PDF形式でダウンロード (746K)
ノート
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諏訪 雅頼, Fatma YESIL, 中塚 由加里, 有馬 彰秀, 塚原 聡原稿種別: ノート
2016 年 65 巻 4 号 p. 203-209
発行日: 2016/04/05
公開日: 2016/05/10
ジャーナル フリーAbstract We observed the magnetic orientation of 4-cyano-4'-pentyl biphenyl (5CB), which is a nematic liquid crystal (LC) at room temperature, in contact with the aqueous solution of surfactant. We found that the orientation of 5CB molecule at the interface can be controlled by an external magnetic field. The liquid-crystal thin layer was confined with a copper specimen grid for TEM and a glass coated with octadecyltrichlorosilane, which induced a homeotropic alignment of 5CB. The LC thin layer was immersed in a cetyltrimethylammonium bromide (CTAB) solution. A magnetic field was applied to the 5CB layer with a pair of permanent magnets having a gap of 1 cm. The magnetic-field strength on the sample was controlled by adjusting the position of the magnets. The orientation behavior of the LC was observed via the change of the linear birefringence with a polarized microscope with a crossed-nicols condition. As the magnetic field gradually increased, an orientation change of LC suddenly took place, that is, the Frederiks transition was observed. The anchoring energy was estimated to be <10−6 Jm−2 based on the threshold field of the Frederiks transition. This value is much smaller than that at the interface of the solid substrate in LC device (<10−4 Jm−2). Furthermore, the orientation angle of 5CB could be estimated from the anchoring energy and the retardation of LC thin layer.抄録全体を表示PDF形式でダウンロード (904K)
アナリティカルレポート
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今井 昭二, 山本 祐平, 上村 健原稿種別: アナリティカルレポート
2016 年 65 巻 4 号 p. 211-219
発行日: 2016/04/05
公開日: 2016/05/10
ジャーナル フリーIn order to investigate the long-range transfer mechanism of inorganic small spherical particles in wet-depositions on mountains and remote areas along the Japan Sea in Honshu Island, Japan in 2014 and 2015, other than the summit of Mt. Kajigamori in Shikoku Island, Japan, the residue was obtained with a 0.45 μm pore-sized filter and a single-particle analysis was carried out for ones below 3 μm by using a Low-Vacuum Tabletop SEM-EDX. Particles were classified in six categories according to their compositions. In this work, it was found that a new category type of distribution patterns of the particles (Al-Si particle) was presented, and proposed that depended on the 24 h back-trajectory in Russia near the coast area of Japan Sea. Relationship between classification and back trajectory of air mass was investigated and discussed.抄録全体を表示PDF形式でダウンロード (2268K) -
渡邉 卓朗, 前田 恒昭原稿種別: アナリティカルレポート
2016 年 65 巻 4 号 p. 221-228
発行日: 2016/04/05
公開日: 2016/05/10
ジャーナル フリーIn recent years, the reliability of analytical values is increasingly important. It is therefore essential to use SI-traceable standard materials for calibrations. Although various kinds of SI-traceable standard materials are demanded, extremely limited kind of standard materials are provided. This means that paying much higher cost is required to solve technical problems when preparing SI-traceable standard materials. A determination method using post-column reaction gas chromatography is an easier evaluation method for standard materials, which has already been reported. In this report, we demonstrate a determination of the concentration values of a 58-hydrocarbons mixed gas mixture. In this determination, a 4-components mixed SI-traceable standard gas mixture was prepared and used for the calibration of an analytical instrument. In this application, the concentration level of the primary standard gas and the sample gas were about 1 μmol mol−1. We used the three separation conditions, and the relative standard uncertainty of the variation in separation conditions was 2.10% at the maximum. The combined relative standard uncertainties of the determined concentration values was in the range of 2.11–2.97%. We showed that the accuracy of the obtained values was sufficient to be used as a SI-traceable working standard gas mixture. This means that this determination method is applicable to decrease evaluation cost of SI-traceable standard materials.抄録全体を表示PDF形式でダウンロード (806K)
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