The aim of the present investigation was to study the effect of varying calcium intake on the absorption, excretion and skeletal metabolism of Ca
45 in young rats.
A litter of five growing albino rats ware divided into two groups, and one was fed with the standard diet (calcium content 0.47%) and the other with diet poor in calcium (0.15%).
After one month feeding they were given about 7μc isotope calcium by oral administration. After the collection of urine and feces separately, on the 5th day of the experimental period, the animals were sacrificesd and various organs were taken out. Making ash of these samples, the isotope calcium was measured by Geiger-Müller counting tube.
From the findings of this experiment it seems justifiable to draw the conclusion that the degree of calcium “saturation” has an effect on the efficiency of calcium utilization. The efficiecy is greater with depleted than with replenished store.
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