A ketogenic diet therapy has been conducted in addition to usual drug treatment. The subject was an infant who had suffered from an intractable epilepsy with frequent epileptic spasm and had undergone medical therapy by the use of an anticonvulsive for several months without showing any successful effect. The ketogenic diet therapy resulted in a considerable success and the patient could leave the hospital to take the home diet after 6 months' hospital treatment. The program of the ketogenic diet was: “the 4: 1 ratio diet” for 2 years, “the 3:1 ratio diet” for 6 months, “the 2:1 ratio diet” for 6 months and then ordinary foods. However, “the 4:1 ratio diet” which was originally intended for the initial 2 year period has been replaced by “the 3:1 ratio diet” since last November after only 1 year's continuation due to the favorable result of the diet. In order to continue the ketogenic diet for a long period the daily menu should give avariety to the diet at all times. Therefore, an example of a food table suitable for easy menu-making for the home diet as well as for the hospital use has been introduced. By using this table, it is very easy to prepare a day's menu which conforms to the specified standard in respect to daily amounts of total calories, protein, fat and carbohydrates. *“The 4: 1 ratio diet” means that, in the diet, the ratio of fat (ketogenic materials) to the sum of carbohydrates and protein (antiketogenic materials) is approximately 4:1 by weight.
This report deals with the relation between epidemiological factors (age, sex, marriage, commutation, occupation, hours of rising and sleeping, smoking and drinking habits) and pattern of food intake among 679 workers (electrical machinery workers 103, workers of Japan Monopoly Corporations 97, department store workers 164, local public service workers 315). 1. The breakfast omitting rate had no relation with the hour of commutation, custom of night eating, hours of rising and sleeping. 2. The breakfast omitting rate had significant relationship with marriage, appetite, pattern of sleeping (early rising habit or keeping late hours). 3. The breakfast omitting rate was remarkably observed among the department store workers, because working hours begin later as compared with other occupations, that causes a delay in taking breakfast and usually getting up late.
This study was carried out to evaluate how the protein contents of the diet to modify the chemical toxicity of furylfuramide on JCL: ICR weanling mice. The mice of basal protein groups were fed a AF-2 mixed diet containing 24% protein, and the mice of high protein groups were fed the AF-2 mixed diet containing 31% protein, enriched by casein. AF-2 concentrations in each diet were 0, 0.1 and 0.5% respectively. These AF-2 mixed diets were given ad-libitum to the weanling mice from 3 weeks to 9 weeks of age. The results obtained are summarized as follows: 1) A slight suppression of body weight gain was observed in 0.5% AF-2 mice of basal protein groups during the course of experiment, but at 9 weeks of age, the average body weight of this group came up with the level of other groups. 2) The most remarkable finding at autopsy was the enlargement of the liver observed in AF-2 administered mice both in basal and high protein diet groups. Especially, 0.5% AF-2 mice of high protein groups showed marked liver enlargement. 3) In the histological examinations, marked degenerations of liver cells were noticed in AF-2 administered mice both in the basal and high protein diet groups. 4) In the hematological examinations, Hb and Ht decreased. and serum cholesterol increased in proportion to the concentration of AF-2 in diet both in the basal and high protein groups. As for cholesterol, the increasing rate was suppressed in the high protein groups as compared with the basal protein groups.