In this experiment, the effect of ethanol on the blood pressure was studied by using the spontaneously-hypertensive rats (SHR) developed by K. Okamoto and K. Aoki. As the experimental conditions, 31 male SHR rats aged 8 weeks were divided into three groups, i. e., a control group receiving the standard liquid diet without ethanol and two ethanol groups receiving the liquid diet containing 20% and 30% of the calories as ethanol. The experimental period was 102 days from 8 weeks to 23 weeks of age. The blood pressure was measured by tail-plethysmograph technique. The average amounts of ethanol intakes in the groups of ethanol 20 Cal. % and 30 Cal. % were 1.62 grams and 2.40 grams per day respectively. The average blood pressure of each group was about 140mmHg at the beginning of experiment (8 weeks of age) and attained or reached to the level of 200mmHg after 8 weeks of experiment (16 weeks of age), and the significant differences of the blood pressure among three groups were not found through the whole experimental period. In the group of ethanol 20 Cal. %, the blood pressure after 9 weeks of experiment showed a slight tendency toward the lower level than other two groups. The organs of heart, liver, kidney and spleen showed neither pathological changes nor significant differences in weight among the three groups. The accumulations of liver fat were seen in ethanol groups.
It has recently become important to study the dietary pattern since many of the chronic diseases would be related with food intakes and its pattern. Generally speaking, there are two ways to find the relationship between foods and physiological status, i. e. longituditional case studies and community surveys. The authors studied food consumption and food items consumption of more than 3000 households. With these original data, the authors tried to analyze food intake patterns which might be existing in each local community. Moreover, some of community-food-intake-patterns are similar when the ecological situations of the local communities are alike. The similarity of food consumption is not only fairly useful in practices of health activities, especially nutritional education in the community, but also in etiological studies of chronic diseases. In this study, together with following serial report, we propose a new index which will explain the situation of food consumption of the community with the average food consumption of the nation. Community food pattern is composed of 6 food group index. (x, y). Index X is computed by food amount consumption of the community, while index Y is computed by consumption of food item numbers. From the pattern similarity of the community models, one can have the information of the dietary pattern of the communities. However this model is not a mathematical model but an analogus model, so that the similarity analysis should be carried out with more detailed method of “similarity analysis”. We intend to apply these indices to other materials furthermore.