Quality control of sera for radioimmunoassay (RIA) have been supplied commercially, as lyophilized sera will become more common due to the easiness of their usage, good reproducibility and the constant supply. This paper demonstrates the improvement in accuracy and precision of analyses proved over the year by the tracking of recovered and recommend proper analysis simplified enough for routine application, the recovery test for the quality control is described with this experience indicating usefulness, this method can be used to control intra-day variation with R values and to control long-term intra and inter-day variation and suits the purpose that is not supported by commercial control sera well.
A gamma-ray scattering density meter is investigated, in which a measuring head of 22 mm outer diameter composed of a 35 MBq (0.95 mCi) 137Csgamma-source, a 50 mm thick lead shield, and a 10 mm dia.×25.4 mm BGO scintillator is connected with a photomultiplier tube by a 10 mm dia.×5 m optical fiber cable. The count rate reduction in gamma response of the meter can be compensated by adjusting amplifier gain to keep normal count rate. A calibration curve prepared by using samples of water, sand, small stone, or their mixture showed a positive slope with increasing bulk density of the range between about 1 and 2 t/m3. The density in this range may be determined with a relative statistical error (1σ) less than 0.5 % in 1 minute measurement, and an effective depth resolution of about 10 cm.
About 15% of CPR-U was not correspond between two kinds of kits in the routine assay, which were produced by different pharmaceutical corps, and also it is realised that the effect of the preservative, storage condition and buffer dilutions can not be overlooked in quality control programmes. Based on these problems, following results are concluded; (1) Urine preservative: NaN3is better than toluene. (2) Urine CPR was stable for added preservative at 4°C for two weeks. (3) Diluents may effect the CPR-U results, if not kept in good condition. The role of the makers in supporting improved quality in clinical laboratory tests will be expeetated.
A newly developed dual photon absorptiometry system (DCS-600, ALOKA Co., LTD.) using two monochromatic X-γays for the determination of bone mineral in the peripheral bone was fundamentally studied, in comparison to single photon absorptiometry sytem (SPA) . The accuracy and precision in DCS-600 were equal to or better than SPA system. Furthermore, in DCS-600 the forearm could be imaged, and the manupulation was easy. Thus DCS 600 was found to be a good instrument as a quantifying system of bone mass.
The clinical significance of serum SCC antigen level was evaluated by the monoclonal antibody method (SCC·RIABEAD Dinabot Co. Ltd) . Patients with squamous cell carcinoma showed a high positive SCC antigen level and positive rate elevated with the advance of the clinical stage. The serum SCC antigen level was decreased by treatment, and it increased again before obvious clinical recurrence was recognized. The results suggest that measurement of serum SCC antigen level is usef ull as a follow up of cancer treatment.