The linearity for dose response and the dilution technique of deeply colored solution and others in titanium sulfate dosimeter were investigated. The dosimeter is a 0.01 M titanium sulfate solution saturated with nitrogen. All photometric measurements of titanium complex produced by irradiation were carried out at a wavelength of 410 nm. Dosimeter solutions were stable for 1080h at 25°C after irradiation. The dosimetry was not affected entirely by dose rates in the range of 104-106R h-1, but affected considerably by irradiation temperatures. The dilution of deeply colored dosimeter solutions produced by high γ-ray dose irradiation was carried out succesfully using unirradiated dosimeter solutions (0.01 MTi (S04) 2and 1N H2SO4) . This dosimeter saturated with nitrogen makes it possible to determine high γ-ray doses in the range from 104-106Gy in accuracy ± 5 %.
In spite of the wholesomeness acceptance of irradiated foods by the FAO/IAEA/ WHO Joint Expert Committee on Food Irradiation 1981, there are some concerns about its safety, in which the induced radioactivity in the irradiated foods is the matter of primary concern. It is, therefore, very important to show clear data of radioactivity in irradiated foods to the public in order to clear up their misunderstanding. Especially for irradiated spices, this is an urgent problem because they are expected to circulate in the international market in the near future. Therefore, in this study, the authors tried to examine whether or not radioactivity could be induced in the black pepper irradiated with 10 MeV electrons theoretically and experimentally. For the theoretical evaluation, elemental composition of the sample were analyzed and photonuclear reactions which could produce radioactivity in the sample were investigated based on the data already published. Then the sample was irradiated with 10 MeV electrons from the linear accelerator and radioactivity was measured by gammaray spectrometry. As a result, the pattern of gammaray spectra was all the same between irradiated sample and background.
We have developed an automated system for regulating access to a potentially hazardous facility, the radioisotope laboratory, and for recording radioisotope use. A feature of this system is that information entered by each user is directly compiled to a final document. This system is easily implement and has functioned without any problems. It has lead to a drastic reduction in labor and provides accurate documents in the management of a radioisotope laboratory.
The accumulation rate and velocity of99mTc-hydroxymethylene diphosphonate (99mTc-HMDP) in hip joints were determined within four minutes after a bolus of injection of99mTc-HMDP in the patients with hip joint disorders. There exist a significant relationship between accumulation velocity of99mTc-HMDP in the affected joint and serum osteocalcin in the patients with eight cases of degenerative osteoarthropathy and six cases of femoral necrosis. This result indicates that the accumulation velocithy of99mTc-HMDP in the affected joint is likely to become a marker of bone turnover in hip jiont disorder.
Two-site immunoradiometric assey (IRMA) for human parathyrin (PTH1-84) is specific for the intact, secreted, biologically active 84 amino peptide. This system incorporates two-different polyclonal antibodies to human intact PTH and has several technical advantages for use. This assey could detect the wide range of in patient with hypo-, hyperparathyroidism, chronic renal failure and hyper calcemia with malignancy, especially distinguishing the level of human intact PTH in hypoparathyroidism from in normal.
Levels of parathyroid hormone (PTH) and osteocalcin in hypomagnesemic sera of chronic alcoholism patients were carried out to evaluate the roles of chronic alcohol poisoning on bone metabolism. Serum γ-GTP activity showed inverse relationships among serum Mg and osteocalcin in these patients and PTH levels was also more decreased in these patients than in the health subjects. These results indicated that the direct actions of alcohol might be brought about the deterioration of bone metabolism, due to being induced to the decrease of serum PTH and osteocalcin levels by chronic alcohol poisoning.
Relative bone mineral content in the lumbar spine was measured by phantom B-MAs with the apparatus of computerized tomography in order to study the relationships between bone mineral content with age and parathyroid hormone in sera of randamized out- and in- patients and the hemodialysis patients. There exists the significant difference between mal and female in the loss of bone mineral content of three groups.