This paper describes a software package that manages dosimeter inventory and exposure data with a personal computer. The computer, connected with the access control system, deals with both records of the film badge (FB) supply to workers and the ordering of new FB for a company, processes exposure data and produces reports. The software not only ensures accurate reports but also significantly reduces the tedious labour involved in managing the control system.
The gamma irradiation system with variable effective half-life function has been developed, which provides the low dose rate gamma irradiation field by two137Cs sources (3.7×1010Bq and 7.4×1011Bq) . This apparatus was designed to give an exposure at varying low dose rate in accordance with a biological half life of radioactivity in organisms by selecting one of two irradiation methods. The first irradiation mode uses the spatial attenuation by four movable irradiation tables and the other uses the radiation attenuation by an iron filter. Both of these are driven by pulse motors using the personal computer control. The characteristics on spatial gamma-ray irradiation field were measured using calibrated ionization chambers for gamma dose and NaI (Tl) scintillation ionization chambers for gamma dose and Nal (Tl) scintillation counter for gamma spectra. The irradiation field covers the dose rate between 2.5×10-3C kg-1min-1and 1.2×10-7C kg-1min-1. The energy spectrum information including scattered radiations are also obtained. The apparatus was proved to be useful in the experiments for the irradiation of mice at varying dose rate to simulate tritium in internal irradiation.
The patients receiving maintenance hemodialysis were divided into two groups in the absence and the presence of bone pain and investigated the markers of bone pain in these patients. These results suggested that the duration of receiving hemodialysis, serum cont rations of alkaline phosphatase, osteocalcin and parathyroid hormone became to be the markers of bone pain.
Two antibody method of aldosterone RIA kit was investigated. This kit was measured directly without extracting the aldosterone. On fundamental studies, stability of standard curve, reproductivity, recovery test and dillution test were obtained good results. On clinical studies, the diurnal variation of serum aldosterone concentration in normal child and adult was correlated well to that of concentration of cortisol and ACTH. The concentration of three hormones was the highest in the early morning and it was the lowest in midnight.
The“sandwich”or noncompetitive reagent-excess, 2-site immunoradiometric assay (2-site IRMA), ELISA, USERIA, and related techniques, have several advantages compared with the traditional or competetive radioimmunoassays. IRMAs can provide improved sensitivity and specificity. However, IRMAs present some practical problems with nonspecific binding, increased consumption of antibody, biphasic dose response curve, (high dose hook effect), and may require special technieues for dose response curve analysis. We anticipate considerable growth in the popularity and importance of 2-site IRMA.