Obtaining abundant information on the expression of many genes occurring simultaneously in cells by theDNAarray analytical technology is very important in the life science research. However, the data processing method affects the result greatly. In this paper, the program named asEX-ARRAYwas prepared to verify the macro-array data, which was analyzed by 33P labeling probe, and examined. The original data was obtained from the software Array Gauge and was processed by setting two different backgrounds. Two resulting data were exported as text files, and were input toEX-ARRAY.Processing through this program enhanced the reliability on data analysis.
An automated system for preparation of11C-methylated compounds from [11C] methyl iodide, manufactured bySumitomo Heavy Industries Ltd., was adapted for the loop labeling method using [11C] methyl tiflate. Two 2-way valves on an exchangeable tray were replaced with 3-way valves and a furnace for heating anAgOTfcolumn at 200°C was added. The automated system successfully produced [11C] raclopride and [11C] N-methyl-3-piperidyl benzilate in 0.96-1.1GBq and 1.0-1.3 GBq, respectively, at 40 min after the end of bombardment.