Thiamphenicol glycinate hydrochloride (TP-G) was administered to 65 bull calves of a dairy suffering from infectious bronchitis and pneumonia.
1. Of the calves, 92.3% recovered from the infectious diseases after three successive intravenous administrations of 3 doses of TP-G, containing 20 mg theiamphenicol (TP), 10 mg and 20 mg/kg of respectively.
2.
Pasteurella multocida, Ureaplasma sp., and
Mycoplasma boviswere isolated from the pituita of 20, 11, and 8 calves. respectively, of 20 examined before administration of TP-G.
3. Penicillin and TP had a strong antibacterial action on
P. multocida. Macrolide antibiotics, tetracycline, and TP were highly effective against
M. bovis.
4. No side-effects of TP-G were observed.
5. TP-G was judged to be an effective agent against bacterial infections of the calf respiratory system.
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