Liver biopsy at the laparotomy and right omentopexy were conducted in 40 cows with displaced abomasum. Six cases of poor prognosis showed serious clinical signs and fatty infiltration in the liver, and 34 cases of good prognosis were divided into 5 classes of liver fatty infiltration: severe (11 cases), medium (7 cases), mild (8 cases), normal (5 cases) and others (3 cases). The cases of poor prognosis showed higher levels of the hematocrit and ALP than recovered cases with severe liver fatty degeneration as well as higher levels of hematocrit, total bilirubin, GOT, LDH, ALP and ketonuria than those with medium or lower degree of liver fatty degeneration. These results indicated that most cows with displaced abomasum were found to have fatty infiltration of the liver and that the cases of poor prognosis had more serious fatty infiltra tion of the liver. In cases with serious fatty infiltration of the liver, higher levels of the hematocrit and ALP might be indicative of poor prognosis.
In a diabetic 4-year-old Japanese black cow, the urinary concentration of N-acetyl-β-D-glucosaminidase (NAG) and NAG index were 8.4U/l and 20.2U/g, respectively, being higher than in non-diabetic cows. The form B NAG isozyme was 66.6% in the present case, while 20% in non-diabetic cows. In the diabetic case, the renal function was lowered. Histopathological examination revealed granular degeneration of the proximal convoluted tube, hyaline degeneration of collecting duct and severe focal interstitial nephritis indicating that the increase of NAG isozyme B is due to the renal tubular and interstitial lesions.
Five stillborn fetuses and fetal placentas from a sow with abortion occurring at 2 weeks before the expected delivery date were examined. The fetal placentas were cloudy and the fetuses had subcutaneous edema, reddish thoracic and peritoneal fluid and epicardial and renal hemorrhages. Microscopy revealed villous necrosis in the placentas, with numerous gram-positive cocci. Focal necrosis of liver, cerebral meningitis and bacterial embolism were recognized in the fetuses. Streptococcus group C was purely isolated from 3 of 5 fetuses. No virus was isolated. Antibodies against Japanese encephalitis virus and porcine parvovirus were not detected.
An outbreak of chicken anemia virus (CAV) infection occurred in 90-day-old growing chickens in August 1992. Affected chickens showed anemia, very low γ-globulin level, multiple petechiae in some muscles and anemic bone marrow. Microscopy revealed lymphocyte depletion in lymphoid tissues and the bone marrow. CAV was isolated from the liver of affected chickens, and no antibodies to several major chicken viruses were detected, suggesting that immunodeficiency predisposed to the present cases.
The hemodynamic effect of nitroglycerin ointment (NGO) administered on oral mucosa was investigated at 30 min intervals in five normal and five experimental mitral regurgitation (MR) dogs. After administration of 15 or 100 mg, the mean arterial pressure (MAP) decreased in all cases. MAP were observed attaining the lowest at 90 and 30 min in the normal and MR groups respectively and subsequently returning to the level before administration except for the MR-15 mg cases. Showing a significant increase even after 150 min. The mean pulmonary arterial pressure (MPAP) decreased and subsequently returned to the level before administration except for the MR-15 mg cases. Showing significant increase after 300 min. In the normal-15 mg cases, there were significant increase in cardiac index at 270 min and in heart rate at 30 min but not in other cases. The double product (systolic arterial pressure × heart rate) decreased in all cases, later significantly increased at 240 min in the MR-15 cases.
Chitosan oligomer (SD) was much more effective on canine abscesses produced by inoculation of Staphylococcus aureus than antibiotic. Of 5 canine and 17 feline cases with purulent wounds, a single or two doses of SD were effective in 16 cases (73%) with decreasing exudate.
A 14-year-old spayed female Japanese cat presenting continuous lacrimation from the left eye for 1 month, had a light pink colored mass on the iris of the left eye with corneal edema. The mass rapidly enlarged and the left whole eye was enucleated 4 months later. Though the postoperative condition seemed well enough, a right head tilt and right circling appeared on day 72 after operation, and became severe day by day. The cat died on day 82 after operation with sudden cessation of breathing. Histopathologically the enucleated eye showed malignant melanoma in the ciliary body, iris, cornea, choroid and bulbar conjunctiva. Metastasis was detected in the kidney and brain stem.
Tumors were detected in 670 of 9, 156, 633 slaughtered pigs examined during 1970-1990 at the meat inspection office of Kanagawa Prefecture; 146 lymphomas, 124 nodular hyperplasias of liver or liver cell adenomas, 121 nephroblastomas, 109 malignant melanomas, 69 ovarian hemangiomas and 33 uterine leiomyomas. Lymphomas, malignant melanomas and nephroblastomas were more frequent in the fattening pigs, while nodular hyperplasias of liver or liver cell adenomas, ovarian hemangiomas and uterine leiomyomas in the retired sows. The incidence of nephroblastomas in sows and gilts were about twice more than that of boars and hogs, and higher occurrence rate in the mixed Hampshire breed was suggested. The incidence of malignant melanomas seemed to have decreased with decreased number of colored breed.