Twenty-five 30-month-old guinea fowls, Numida meleagris, naturally infected with Capillaria perforans and Heterakis sp. were divided into 3 groups, A, B, and C). Groups A and B were treated with 0.05 per cent of Parbendazole contained in the ration for 24 and 48 hours, respectively. Group C served as an untreated control.
1) There was a difference in the fecal egg, count of capillarids between the treated and untreated groups. Cecal worms showed a more makred decline in the count in the trated groups than in the untreated one.
2) Cecal worms were detected mostly from feces 2 to 5 days after treatment, but capillarids were not. Autopsy conducted 0.5, 1.5, and 2.5 months after treatment revealed the decreasing number of cecal worms and capillarids remaining in the digestive tract.
3) Two weeks after treatment microscopical observation revealed a marked proliferatin of epithelial cells in the mucous membrane of crop and esophagus and infiltration of eosinophilic granulocytes and small round cells in the lamina propria mucosae. These lesions were improved in the treated groups 1.5 months and almost completely repaired 2.5 months after treatment.

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Liver cirrhosis was detected at a high rate from among pigs brought to the Omiya Abattoir, Saitama Prefecture, by a swine husbandry man over a period of January to May, 1969. The affected pigs presented no marked gross changes other than liver cirrhosis. Histologically, the liver showed thickening of the stroma and formation of septula, paeudolobules, or pseudo-biliary ducts. Hepatic cells were mostly affected with focal vacuolar degeneration, necrosis, and colliquation. Large nucleated or polynuclear cells appeared. In the kidney, vacuolar degeneration occurred to epithelial cells of some uriniferous tubules, and large nucleated and polynuclear cells appeared. The ovary had follicular cyst.

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