1. Chemical wounds were caused artificially with concentrated sulfuric acid upon the skin of the side wall of the thorax in dogs. Then α-Chymotrypsin (CT) alone was applied locally to the wounds or administered systemically to the dogs. 2. The healing process was shorter in two treated groups than in an untreated control group. 3. The curative effect of CT seemed to be a little more excellent macroscopically in the local application than in the systemic administration. Histologically, however, there was little difference in such effect between the two methods of medication. 4. It seems that some truth may be contained both in the secondary action theory and the direct action theory to explain the anti-inflammatory action of CT.
Various food additives were examined for effect upon Vibrio parahaemolyticus (VP) in relation to pH and salt concentration. 1. When sorbic acid and dehydroacetic acid were added to media at a concentration of 0.5 and 0.2 per cent, respectively, they displayed inhibitory effect on the growth of VP, particularly at a lower value of pH than the control medium. 2. Nitrofuran derivatives showed a remarkable inhibitory power over the growth of VP. 3. None of 12 dyes, authorized as food additives by law, exhibited any inhibitory action against the growth of VP, except ponceau SX which had a weak inhibitory power.
1. Postmortem findings on some bulls suffering from reproductive disorders lent support to the results of antemortem tests performed on them. Nearly good correlation§ were present between the white blood count and suppurative inflammation, between eosinophilia and liver flukes, and between the Gross reaction and liver dysfunction. dysfunction. 2. A total of 33 bulls were examined in the field. Some of them which had not been used for insemination purposes on account of reproductive disorders gave abnormal results at least in one of the tests conducted. Serum protein was high in level, liver dysfunction was suspected from a positive Gross test' or a high eosinophilic count was obtained in spite of a negative test of liver fluke infection in some of the bulls regarded as healthy and used for reproduction. 3. The results of the tests performed suggest that reproduction disorders may be caused by complicated factors in bulls and that it may be induced by some medical and surgical diseases in addition to summer sterility and sexual dysfunction caused by endocrinological factors.