The distribution of heartworms in the right heart and adjacent vessels was studied by two-dimensional echocardiography (2DE) in 77 dogs with canine heartworm disease. Of 13 asymptomatic dogs, six demonstrated heartworm echoes (HE) in the pulmonary artery (PA) but the remaining seven did not. Of 36 chronic dogs six showed a few HE moving back and forth within the right atrium (RA) and right ventricle (RV) during the cardiac cycle. All of them were terminally ill and subsequently died. Of the remaining 30, 18 had HE in the PA, but 12 did not. The other 28 dogs of the 77 manifested the caval syndrome. Of them, 4 small dogs presented atypical clinical signs of this condition. In the 28 dogs, large masses of heartworms were in the venae cavae and RA and moved collectively into the RV during the diastolic stage.
In conclusion, the PA was the habitat of adult canine heartworms in the vast majority of chronic cases, as well as in asymptomatic dogs with heartworms.

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Intra-articular surgical repair of cranial cruciate ligament rupture (CCLR) was performed in clinical bovine cases (Holstein-Friesian, 9 and 10 years old) and 2 experimental ones (Japanese Black, one year old). It was conducted by a modified over-the-top procedure and the patellar wedge technique for replacement of the ligament. It was unsuccessful in the clinical cases because of the occurrence of femoral fracture by failure of care, but brought about marked improvement in the experimental cases. It was found that the surgical repair was effective for CCLR.

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In November, 1983, bloody diarrhea and fever were noticed in 32 fattening pigs on a farm in Niigata Prefecture. All the pigs except one, died. Autopsy revealed the black watery contents, formation of pseudomembrane, and a large number ofTrichuris suis organismsin the cecum and colon.Escherichia coliandClostridium perfringenstype A, includingα-toxin and enterotoxin-producing strains, were isolated from the small and large intestines. The cause of death was presumed to be a heavy infestation ofT. suisaccompanied with infection ofCl. perfringenstype A.

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The indirect hemagglutination (IHA) test was used as a diagnostic method for infectious bovine rhinotracheitis:(IBR) virus infection in the field. Formalized sheep red blood cells were treated with tannic acid, sensitized with IBR virus, and used for the test as antigen. The antigen could be stored at -80°C for at least 3 months. Bovine sera were collected from herds where IBR infection was observed. Serum antibody against IBR virus could be detected specifically in sera collected in herds in the early and late stages of infection. The antibody titers determined by this test were almost equal to those by the serum neutralization test with complement. The IHA test was so sensitive that it could detect antibody early. It was also reproducible. It was considered to be a valuable means for the diagnosis and epizootiological studies of IBR virus infection.

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Of 540 milk samples collected from cows medicated with no antibiotics, 55 (10.2%) were positive for the paper disk test (a test of residual antibiotics in milk). Particularly, the positive rate (19.7%) was high for milk samples showing a cell count of more than 300 thousand/ml.
The inhibitory clear zone of the positive milk disappeared when 1mg of trypsin to 1ml of milk. Loctoferrin one of the Cell inhibitors in milk, increased significantly in concentration in milk samples showing a bacterial count of more than 510 thousand. The lactoferrin concentration was more than 0.49±0.14mg/ml. in the positive milk samples. The sensivity of human lactoferrin in the paper disk test was 0.5mg/ml.
From these results, lactoferrin in milk was considered to be one of the factors to makea clear inhibitory zone in the milk, such as one produced by an antibiotic in the paper disk test.

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An indirect method of measurement of blood pressure was evaluated by the ultrasonic Doppler technic in unansethetized dogs. The ultrasonic device used was composed of cuff and an ultrasound transducer. In order to ausculate a good audible signal and estimate an accurate blood pressure value, examination was made on the position of the transducer for monitoring the blood stream, that of the cuff for occluding the blood stream, the holding position of the dog, and the validity of repeated measurements. A valid value was obtained by monitoring the blood stream of the ulnar artery, occluding the arterial blood stream above the elbow joint, and holding the dogs in the upper part of the foreleg.

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Snuffle broke out on an Angora rabbit farm. The clinical signs were sneezing, running nose and snuffling. A crisis was recognized in both breeding and growing rabbits.
Five affected animals were sacrificed.Bordetella bronchisepticaandPasteurella multocidawere isolated from nasal swabs. The common macroscopic changes were retaining of mucus in the nasal cavity and the paranasal sinus. Histological examination showed catarrhal inflammation of the nose and osteolysis of the turbinate.
Tweenty breeding and nine growing rabbits were examined the saturation ofB. bronchiseptica. B. bronchisepticaandP. multocidawere isolated from the nasal swab in 86% and 17% of rabbits, respectively. Agglutination antibody unit against B.bronchisepticawas×98 in breeding and×25 in growing rabbits.
We consider that the main causal agent of this outbreak isB. bronchiseptica.

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Spondylolisthesis occurred in a castrated 18-week-old pig showing a clinical sign of ataxia or paralysis of the hindlimbs. The gross lesion was characterized by displacement of the first and second lumbar vertebrae, with resulting compression of the spinal cord. Histologically, the spinal cord involved showed degeneration of the white matter and degenerative or necroticnerve cells in the gray matter.

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There piglets of the same litter, 45 days old, died suddenly without showing symptoms on a farm in Yamaguchi Prefecture in May, 1984. Autopsy revealed much fibrin adherent to the pleura. Alphahaemolytic streptococci were isolated almost pure from the brain, lung, liver, kidney and hydrothorax.
Judging from their biochemical characteristics and serological typing, they were identified as those of “Streptococcus suis” type I/II (Group R·S).

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