In a thoroughbred foal, abnormal formation of both eyeballs were noted during birth. Through ultrasonography, the ocular architectures, such as the cornea and crystalline lens, were indistinct, and uniform echo images were observed in the vitreous cavity. In a computed tomography (CT) examination, multiple tissues that indicated a high CT value were observed in the vitreous cavity. The absence of the lens and milk-white module formation on the pupilla were confirmed by gross observation. Histological examinations revealed the absence of normal ocular architectures, including the lens, vitreous body, choroid, and retina, and the formation of ectopic tissues such as the cartilages and gland in the eyeballs. All these findings may indicate that the ultrasonography and CT examinations are useful for the diagnosis of teratogenic ocular diseases in horse during life. ―Key words : computed tomography, foal, microphthalmia.
The optimal iotroxate meglumine dose in dogs for CT imaging by drip infusion cholangiography was examined against changes in CT values in the biliary duct system and apparent gallbladder volume over time and the visualization grade of the biliary duct system in three-dimensional CT (3D-CT) images, to investigate the most useful dose of the contrast medium and the optimum timing of imaging following administration. The contrast medium was intravenously administered in doses of 1 ml/kg (in two cases), 1.5 ml/kg (in five cases), 2 ml/kg (in five cases) or 2.5 ml/kg (in one case) for 10 minutes, and CT imaging was performed before and immediately after administration and repeated thereafter at 10-minute intervals. The results indicated that 1ml/kg of the contrast medium was insufficient to visualize the biliary duct system. The increase in CT values was limited under a 2 ml/kg dose compared to that under a 1.5 ml/kg dose. Visualization of the biliary duct system in 3D-CT imaging was, however, clearer under a 2 ml/kg dose. The biliary duct system was most properly visualized when imaging was performed 20 to 40 minutes after completing administration of the contrast medium. It was therefore considered that DIC-CT imaging of healthy dogs under anesthesia would properly be performed 20 to 40 minutes after completion of administration if 2 ml/kg was applied for 10 minutes.
A methicillin-resistant Staphylococcus intermedius group (MRSIG) was isolated from 28 diseased dogs and seven diseased cats in one hospital from January 2007 to February 2009. MRSIG was isolated from samples of the skin (n＝18), subcutaneous abscess (n＝7), eye discharge (n＝5), urine (n＝2), ear discharge (n＝1),nasal discharge (n ＝1), and vaginal secretion (n ＝1). Thirty-three of 35 cases (94%) had a history of antimicrobial treatment. All MRSIG isolates were resistant to amoxicillin-clavulanic acid, cephalexin and cefdinir,and 80% and 74% of MRSIG were resistant to gentamicin and ofloxacin, respectively. All isolates were sensitive to doxycycline, and 46% and 34% of MRSIG were sensitive to chloramphenicol and fosfomycin, respectively. Since 91% of cases had been resolved or improved after administration of suitable antibiotics, it was considered that these sensitive antibiotics were effective in vivo.
Spontaneous keratitis and alopecia were detected respectively in 2 of 17 chinchillas (Chinchilla laniger) that had been bred in our laboratory. Staphylococcus aureus was isolated as a pure culture from each lesion. The isolates were sensitive to ofloxacin. After instillation of a new quinolone and a drug for the treatment of cornea ulcers five times per day for five days, followed by administration of vitamin B2 and the cornea ulcer drug twice daily for 34 days, one chinchilla, which exhibited keratitis, was completely cured. The other chinchilla, which had alopecia on the leg, was completely cured by treatment with a liniment of the new quinolone once a day for four days. S. aureus was not detected in any of the cured lesions. The data demonstrated that keratitis and alopecia on the leg can be caused by spontaneous S. aureus infection in the chinchilla, and that the treatment described here is effective against this bacterium.
Two large dogs with nasal tumors were treated with orthovoltage X-rays and cautery via the nostrils. One dog underwent radiotherapy and ultrasonic aspiration and cautery of the nasal cavity. The other dog underwent radical excision of the shrunk dorsal lesion after radiotherapy and cautery of the nasal cavity. Both dogs were disease-free subsequent to treatment and survived without recurrence for more than one year.
The authors conducted an abattoir survey to determine the prevalence of antibodies against hepatitis E virus (HEV) and the HEV gene from 120 fattening pigs reared on 13 farms in Fukuoka Prefecture, Japan. IgG and IgM antibodies against HEV were detected in 73 (60.8%) pigs from 12 farms and two (1.6%) pigs from two farms,respectively. The HEV gene was detected in five (4.1%) pigs from three farms. The HEV gene is not usually detected in shipment pigs infected with HEV during the growing period. The HEV gene was detected in IgG antibody negative pigs, showing that HEV infection occurred just before shipment in the fattening pigs brought to the slaughterhouse.