A total of 160 dogs of 21 breeds were classified into four groups, I to IV, or well, mild, moderate, and severe, respectively. The mean values of Hb. A/G ratio, TP, and Ht measured in each group were plotted on four parallel lines drawn at the same intervals. The resulting hemospectrogram was compared among the groups. In it, a broken linear graph ran from the upper to the lower part within a range of normal values in group I. It showed a shift of the A/G ratio to the left beyond a range of normal values in group II. It exhibited a shift of Hb and the A/G ratio to the left beyond a range of respective normal values in group III. It presented a shift of Hb, the A/G ratio, and TP to the left beyond a range of respective normal values and a shift of Ht to the right beyond a range of normal values in group IV. These results seemed to indicate that the hemospectrogram might be available for judgment of severity of disease.
Thirty-five dogs were used to select a site of measurement of venous pressure practical for the private practice. As a standard point of measurement, a site was selected in a position one-third from the lower end of the space between the manubrium sterni and the trachea in a dog lying on the back. Then comparison was made among central venous pressure (VP), right jugular VP, and left femoral VP with some results.
Diagnostic records on 208 indigenous Japanese Black cattle revealed that fat necrosis had been found in the adipose tissue around the colon in 82.7% of the cattle, that around the rectum in 42.3%, and that around the kidney in 27.9%. Actual examination of 33 cattle encountered at the abattoir revealed that fat necrosis had been found in the adipose tissue around the colon in 88.0%, that around the rectum in 27.3%, and that around the kidney in 30.3% Grossly, necrotic masses of fat varied in size from the tip of the little finger to the head of the human adult. They were surrounded by a thick layer of connective tissue, causing stenosis or occlusion of the organ. Histologically, necrotic fat cells were enlarged a little, containing needle-like crystalline bodies arranged radially in the cytoplasm. They were surrounded by foam cells and syncytia of these cells, as well as giant cells against foreignbody.
Chlorobromofebrifugine (CBF) was evaluated for anticoccidial activity in chicks and cultured cells infected with various species of coccidia. The results obtained are summarized as follows. (1) Battery tests were carried out in chicks experimentally infected with oocysts of laboratory strains of Eimeria tenella, E. acervulina, E. maxima or E. brunetti. Dietary administration of 3 or 6 ppm CBF was found effective, but 1.5 ppm was considerably ineffective. Two field isolates, F-1 resistant to amprolium and clopidol and F-2 to these drugs and robenidine, were used in battery tests with CBF and gave results similar to those given by the laboratory strains mentioned above. (2) The appearance of immature and mature schizonts was conspicuously inhibited when 0.01 or 0.001 ppm CBF had been added to the culture medium of E. tenella in BHK 21 cell culture.