A toy -poodle was affected spontaneously with the Cushing syndrome, manifesting systemic alopecia, an increase in abdominal girth, dipsia, polyuria, polyphagia, and a loss of elasticity of the skin. Initial examination revealed leukocytosis, a low ratio of eosinophils to lymphocytes, hyperglycemia, hyperlipemia, high levels of GPT and ALP activity, and large value of plasma hydrocortisone.
In the rapid combined test, the hydrocortisone value was 20.0 and 9.0μg/dl before and 12 hours after loading of dexamethasone, respectively. It was 56.0 and 60.5μg/dl 1 and 2 hours after loading of ACTH. The diagnosis of ACTH-dependent bilateral adrenal hyperplasia was made from these findings.
At first, unilateral adrenalectomy was performed only to fail to alleviate the clinical symptoms. Then, o, p'-DDD was administered. Six doses were given at a week's intervals, but no hydrocortisone decreased in level. Subsequently, the drug was administered daily for 10 consecutive days, inducing anorexia and oliguria. So the treatment was suspended. Two weeks later, however, the hair began to grow in the body and the hematological findings characteristic of the Cushing syndrome were found alleviated.

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Five milking cows were affected with yew poisoning on a farm in 1981. They manifested clinical symptoms several hours after they atemany leaves and twigs of the yew dumped adjacent to the grazing paddock. Two of them died 15 and 18 hours later, and the others recovered 24 hours later. Activity, appetite and rumination were lost, and trembling of the four legs, short ening of breath, and irregular heart sound were observed. Many leaves and twigs of the yew were present in the rumen at autopsy. Plant alkaloid was detected from the rumen juice. From these results a diagnosis of yew poisoning was made in these cows.

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Bicozamycin was examined for effect on 19 piglets of 2 litters infected withEscherichia coli. These piglets recovered after daily treatment with it for 3 days, regardless of the difference in dose used. Drug-resistant strains of E. coli were isolated even from day-old piglets at a high frequency. They decreased in frequency of isolation after 1 month probably because of the noapplication of common therapeutics.

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Castrated male Holstein cattle for fattening began to suffer from lacrimation, rhinorrhea, a staggering gait, and blindness. Autopsy revealed remarkable edema in the subcutaneous and intermuscular interstitial tissues in the head, neck, and anterior part of the breast. Microscopically, edematous enlargement was distinct in the intermuscular tissue, which contained degenerative small blood vessels, and atrophy or hyaline degeneration of muscle fibers was noticed. Biochemical examination showed that the plasma vitamin A level was minute in 5 cases and 22.1 IU/dlor less in 4 cases out of 10 cases examined.

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Small terrestrial animals, such as oribatid mites and coprophagous beetles, the supposed first intermediate hosts ofM. paucitesticulus, were examined for cysticercoids with negative results.
Crickets and cockroaches were experimentally infected with cestode eggs with negative results. Many species of birds and mammals were examined for the tetrathyridium, which was detected from copper pheasants and green pheasnts. The tetrathyridium detected was elliptical or spherical in shape and 1.2×2.3 mm in size. White worm cysts, each containing a tetrathyridium, were 2.0 to 2.5 mm in diameter and collected from visceral organs and muscle of host birds.
Final hosts were raccoon dogs, foxes and dogs. In dogs the cestodes passed gravid proglottids into feces 13 days after infection with tetrathyridia. The longevity of the cestode was 8.5 years in a dog experimentally infected with a tetrathyridium.

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An ear tag, used for the identification of domestic animals, was utilized in the treatment of colpoptosis in 5 swine. It was attached to the middle part of the labium pudendi on each side to the deepest possible extent. A thread was passed through it and fastened in the same manner as coiled suture, so that the vulva might be closed.

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Six calves 15 days old received a daily dose of 20mg/kg of furazolidone with a milk replacer. They began to show peculiar signs at 4-5 days of medication. Two of them died at 5-6 days, one was condemned at 8 days, and the other 3 recovered. Then 10 days later the 3 calves were given the same dose of furazolidone. They showed the same signs, and one of them died 3 day later, when another was discarded.
The clinical signs were depression and acute hyperexcitability with loud squawking and rapid jumps. After showing nervous signs of extended rigid legs and opisthotonus, calves succumbed.

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