Clinical signs of 5 post-parturient hypocalcemic cows dead or slaughtered with myocardial necrosis (MN cases) were compared with those of 6 cows with milk fever showing recumbency and standing after Ca therapy (MF cases). The clinical signs of the MN cases were anorexia, lateral recumbency, dyspnea characterized by oral breathing and foamy drooling, severe tachycardia and hyperpnea, seemingly being severer as compared with those of the MF cases, and mostly persisting even after Ca therapy. The MN cases had hypocalcaemia as high as that of the MF cases, at the first examination, and the plasma Ca levels turned to normal after Ca therapy in both cases.
Five each of Thoroughbred horses were given intravenously medetomidine (MED)(0.003, 0.005, and 0.01mg/kg), detomidine (DET)(0.01, 0.02, and 0.04mg/kg), xylazine (XY)(1mg/kg) or 5ml of saline. MED (0.01 mg/kg) produced the deepest sedation with most severe and prolonged ataxia. Sedation and ataxia by 0.04 mg/kg DET was similar in degree to those of 1mg/kg XY but more prolonged ataxia was produced as 0.01 mg/kg MED. Sedative effect with less ataxia was produced by 0.005mg/kg MED as 0.02mg/kg DET. Light sedation with short duration and no ataxia was produced by 0.003mg/kg MED.
Three hundreds and seven porcine sera were examined for neutralizing (NT) antibody to the GPE- strain of hog cholera virus using the FS-L3 cell line. They were then subjected to indirect immunoperoxidase (IIP) technique with monoclonal antibody to the pestivirus. The geometric mean titers of NT and IIP techniques were 121.7 and 94.88, respectively, and the correlation coefficient of both antibody titers was 0.813.
Of 38 feline cases with gingivo-stomatitis (GS), 5 were scaled (group I) and 11 were given antibiotics (group II), while 5 received steroids (group III). Another 5 cases were treated with both antibiotics and steroids (group IV), and 7 were given antibiotics, steroids and lactoferrin (group V). In the remaining 5 cases total tooth extraction were performed and then antibiotics were given (group VI). The appetite, and degrees of ptyalism and GS were observed before and after treatments in all cases. GS scores of group VI were significantly smaller (p<0.05) than these of groups II and N, and tended to be smaller as compared to those of groups I, III and V, suggesting curative effects of total tooth extraction in association with antibiotics.
In a 7 month-old female mongrel dog with epileptic seizures in the early morning following the chewing actions, there was no improvement despite the anticonvulsant therapy. Electroencephalogram showed high voltage slow activities with sporadic spike waves, and the case was pathologically diagnosed as canine distemper.
Two cats with the forelimb paresis showed progressive neurological signs involving the spinal cord, brain stem and cerebrum, and the low-voltage fast activity appeared on electroencephalogram. Histopathology revealed meningo-encephalomyelitis due to feline infectious peritonitis virus.
Excreta from 61 pigeons and 35 small birds in pet shops or wild life in Iwate Prefecture, were examined for Cryptococcus neoformans. On sunflower seed agar (Pal's medium) inoculated with 17 specimens of pigeon excreta brown colonies were produced, and the isolates were identified as C. neoformans var. neoformans, based on 37°C growth, urease, KNO3 utilization and phenoloxidase activity.
A 2-year-old Holstein-Friesian cow with posterior weakness and an apparently normal 3-year-old Murray Grey steer were pathologically found to have steatosis in the skeletal muscles at meat inspection. In the Holstein-Friesian case, almost all the skeletal and diaphragmatic muscles of the carcasses contained considerble adipose tissue, whereas the trapezius muscle only was involved in the Murray Grey case. In both cases, steatotic lesions were distributed bilaterally and symmetrically without noticeable reduction in the original muscle volume. Microscopic feature common to the affected muscles in both cases was replacement of muscle fibers by fat cells, being so extensive as to reveal nearly complete absence of muscle fibers in some fascicles. Degenerative/necrotic muscle fibers were scattered in the recognizable muscle tissue. Frequently muscle fiber alteration as characteristic of denervation, showing sharply angulated or flattened atrophied muscle fibers, arranged singly or in small groups occasionally in association with internal nuclei or apparently increased number of nuclei. Neither regenerated muscle fibers nor proliferation of the stromal connective tissue were found.