A 16-year-old neutered female cat was presented to a private veterinary clinic with an ulcerated cutaneous mass on the left side of anus. The mass was removed surgically and diagnosed as an anal sac gland carcinoma on histopathological examination. The cat died on day 82 after removal of the initial tumor. Postmortem computed tomography and following necropsy were performed. Necropsy revealed bilateral anal sac gland carcinoma with locoregional recurrence and multiple systemic metastases.

We experienced two cases of miniature dachshunds with intervertebral disc herniation in which calcified disc materials occupied a large portion of the vertebral canal on computed tomography (CT) scans. Both cases underwent myelography, and after that neurological signs worsened. Surgical removal of the disc materials was difficult because of adhesion to the surrounding tissues which was discovered during hemilaminectomy. It was considered that the calcified disc materials caused the persistent compression of the spinal cord, and the injection of contrast medium in myelography caused neurological signs to worsen. Therefore, when performing myelography in dogs with calcified disc materials that occupy a large portion of the vertebral canal on a CT scan, we should consider the possibility of worsened neurological signs. Moreover, it is necessary to consider surgical procedures and their indications.

An 8-year-4-month-old male Bernese Mountain dog was referred to the Obihiro University of Agriculture and Veterinary Medicine because of a pulmonary mass. The dog was diagnosed with pulmonary histiocytic sarcoma, and a lung lobectomy was performed. The pulmonary mass was confirmed to be histiocytic sarcoma by histopathological examination. We discovered a subcutaneous mass 5 cm in diameter on the right side of the hind flank on the fifth administration of lomustine (on day 119). It was diagnosed as metastatic lesion of histiocytic sarcoma by cytological examination. Therefore, we started administering doxorubicin instead of lomustine, but no effect was observed, and the metastatic lesion increased to a diameter of 11 cm. Then, we started treatment with toceranib phosphate on day 172. The metastatic lesions rapidly regressed. However, on day 301, the re-enlargement of the metastatic lesion in the hind flank and pleural effusion were observed. The patient was treated with vincristine, but died on day 318 without any response. The present case appears to be a rare case in which toceranib phosphate had a dramatic effect on canine histiocytic sarcoma.

From 2017 to 2020, a large number of cases of arthritic swine erysipelas were observed in pigs brought into a slaughterhouse from three farms in Hokkaido, Japan. In this study, we investigated whether 60 isolates of Erysipelothrix rhusiopathiae in each case were derived from wild strains or live vaccine. The results of PCR for serotyping, sequencing of spaA and PCR for determining the vaccine strain using single nucleotide mutation showed that 58 isolates had the same properties as the vaccine strain. In addition, whole genome analysis of 22 of the 58 isolates revealed that all of them were derived from the vaccine. In farms where swine erysipelas outbreaks occur despite vaccination, it is necessary to consider quarantine plans while assuming the possibility of vaccine-associated outbreaks.

A 6-month-old castrated Duroc pig had a fist-sized mass in the left lung that was a light reddish-brown in color. Many millet to walnut-sized grayish-white, white or light-black nodules smaller than the lung mass were observed in multiple organs. In the lung mass, the tumor cells were spindle-shaped and had oblong nuclei and weakly eosinophilic cytoplasm. Tumor cells showed no obvious melanin pigmentation by HE staining, but fine positive granules were identified by Fontana-Masson staining. In addition, tumor cells were positive for Melan‐A, PNL2, TRP2, HMB45 and S‐100 which are markers for malignant melanoma. The visceral nodules showed similar histology to the lung mass. No obvious primary lesions were found on the skin of the entire body, oral mucosa, or eyes. Based on these findings, this case was diagnosed as a melanin hypopigmented malignant melanoma without mass formation on the skin. This is the first report of this kind of tumor in a pig.