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Volume 19, Issue 5
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[in Japanese]1966 Volume 19 Issue 5 Pages 177-183
Published: May 20, 1966
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSDownload PDF (1561K) -
III. Trials on Swine Artificially Infected with LungwormsRYOJI NODA, S. NODA, M. HORIE, M. NOMURA, T. ONISHI, K. YAMAMORI, T. A ...1966 Volume 19 Issue 5 Pages 184-189
Published: May 20, 1966
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSWith the worm count at postmortem and egg count as criteria, Promintic, an injection formula of methyridine, was examined for anthelmintic effect upon Metastrongylus apri when administered to swine in a total dose containing 200 or 250 mg of active ingredient per kilogram of body weight. The dose was given at a time or divided into two equal aliquots to be given at 5 days' intervals by the subcutaneous route. The site of injection was an area posterior to each ear. The swine used were 2 litters of each 10 and 8 pigs. In each litter 2 pigs were left untreated.
The removal ratios, as compared with worm burdens in the untreated controls, at the dose of 200 mg (and 250 mg in parentheses) were 58.9 (55.2)% when administered on the 4th day, 91.6 (98.5)% on the 10th day, 87.7 (99.0)% on both the 10th and 15th days, 71.2 (86.0)% on the 20th day, 75.9 (87.4)% on both the 20th and 25th days, 63.1 (90.5)% on the 30th day, and 72.9 (74.4)% on both the 30th and 35th days of infection. In general, the 250 mg regimen was more effective than the 200 mg, and the two-dose regimen than the one-dose. It is suggested that the drug has a stronger action on male worms than on females.
On the 20th day of infection, no eggs were detected from the feces of the pigs treated earlier than this day. Eggs were found in the feces of many of the pigs treated on the 20th day or later and in those of the untreated controls.
No systemic reactions were noticed. It is concluded that an excellent effect will be achieved by this drug against immature lung worms with one dose of 250 mg/kg, as divided into two equal aliquots and injected subcutaneously at an area posterior to each ear.View full abstractDownload PDF (1060K) -
JUMPEI MIYAKAWA, H. TAKIZAWA, H. NAKAZAWA, S. TSUNODA, H. KANEKO, H. U ...1966 Volume 19 Issue 5 Pages 190-194
Published: May 20, 1966
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSTwenty-two cows, mostly of the Holstein breed, which had not cast afterbirth in 12 hours after parturition were injected with 10 to 50 units of a synthetic oxytocin preparation (atonin-S “Teizo”) mainly by the intramuscular route some time between 12 to 20 hours after parturition. They were collectively called the curative treatment group. The same treatment was given to 8 cows at the same time with, or immediately after, parturition (in 6 cows) and 10 hours after parturition (in 2 cows). The eight cows consisted of some which had suffered from abortion or premature parturition and which were likely to be involved in retained afterbirth, some which exhibited retained afterbirth in the preceding parturition, and some which were lacking in vigor. They were collectively named the preventive treatment group.
As a result, the retained afterbirth was evacuated within 2 days after treatment in 10 cows of the curative treatment group. The regular evacuation of the afterbirth was observed in 4 cows of the other group.The four cows were composed of two which had shown retained afterbirth in the previous parturition, one suffering from abortion in the present parturition, and one exhibiting lowered body strength. These results seemed to demonstrate the effect of the preparation injected.
The successful treatment was naturally brought about by an increase in the mechanical power of expulsion of the uterus by uterine contraction upon the retained afterbirth. In addition, the maternal placenta showed a tendency to contract more rapidly than usual. The preparation injected may have an effect to loosen the connection between the maternal and the fetal placenta.
It was presumed that an optimum dose of injection might be 40 to 50 units. There were no ill effects of this preparation upon further lactation or conception.View full abstractDownload PDF (954K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese]1966 Volume 19 Issue 5 Pages 197-199
Published: May 20, 1966
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESS -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1966 Volume 19 Issue 5 Pages 200-203,208
Published: May 20, 1966
Released on J-STAGE: June 17, 2011
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Giichi Otsuka1966 Volume 19 Issue 5 Pages 204-208
Published: May 20, 1966
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESS1. In addition to streptococci and coagulasepositive staphylococci, lactosefermenting staphylococci were detected from the udders of cows as constantly hardored organisms. The older a cow, the more udders harboring these three types of organisms she was found to have.
2. Cells in the udder increased in number when these three types of organisms were harbored. A more remarkable increase in cells occurred in the presence of lactose-fermenting staphylococci without any ability of fermenting mannitol and gelatin than in the presence of those with such ability.
3. The average values of the viable bacterial count of 1 ml of the first and last portions of milk collected from one cow at the same time of milking were 19, 000 and 11, 000, respectively, in the case of mastitis milk, 10, 000 and 4, 400 in the case of abnormal milk, and 2, 200 and 1, 500 in the case of normal milk.
4. It may be concluded that normal milk shows a viable bacterial count of not more than 1, 000 and a cell count of 100, 000 or less.
5. Phage typing disclosed that all the isolated strains of coagulase-positive staphylococci belonged to group III and had a bacteriolytic area at 42E, 6, 7, 73, 47, 54, and 75. This result indicates that there was only one source of contamination, and makes it possible to assume that those staphylococci may have invaded the udder through the milker's hand and the cow's teat.View full abstractDownload PDF (928K) -
Kazuo Sato, S. MATSUO, K. KAGOTA, S. ITO, K. KAWABE, S. KINOSHITA1966 Volume 19 Issue 5 Pages 211-216
Published: May 20, 1966
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSContagious keratoconjunctivitis, or pink-eye, broke out on a sheep farm over a period from April to September, 1964, affecting 88 percent of 1, 296 animals kept on that farm.
It started with lacrimation, which was followed by photophobia, swollen eyelids, conjunctivitis, cloudy cornea, and vascularization of the cornea. The sense of sight was lost for 7 to 10 days during the manifestation of these symptoms. Prognosis was good.Natural healing was brought about in most cases after a lapse of 30 to 60 days. There was no sex difference in susceptibility for this disease. Lambs were less susceptible and manifested milder symptoms than adult sheep.
Chloramphenicol ointment was not effective for treatment. When subjected to experimental infection with this disease by means of a washing of the infected eye, sheep presented essentially the same clinical manifestations as the spontaneous case after 2 or 3 days, but neither goats nor calves revealed. apparent infection.View full abstractDownload PDF (4670K)
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