1. Dichlorophen (dicestal) tablets possess a high antnelmintic action against the canine tapeworm at a dosage of about 500 mg per kg of body weight of a dog which requires the treatment.
2. No previous treatment of dogs prior to the medicatio nor administration of any purgative after the medication is necessary.
3. In many cases, dogs ceased to pass segments in the feces on the first day or second following the medication. The teniacidal action of the tablets was promptly lethal to the worm, which subsequently under went rapid degeneration and destruction in the intestine.
4. In the experiment on toxity, only one of eight dogs administered with such a large dose as 2, 000 mg/kg showed temporal diarrhea. In the treatment test, only one case of 15 dogs administered with doses of 110 to 500mg/kg showed slight vomiting. Therefore, the tablets can be given to sick dogs and puppies alike.
5. Dichlorophen tablets possess some anthelmintic action against dog ascarids, but no action against other internal helminths, such as Ancylostoma caninum and Trichuris vulpis.

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The authors found it difficult to remove whipworms from piglets by the medication of various drugs. The damage caused by these parasites is not negligible in the authors' breeding stock farm. Such being the case, some surgical operation was employed so that various kinds of liquid medicine might be introduced directly into the cecum. As a result, the following anthelmintic effects were made clear
1) No anthelmintic effect was observed at all when 0.1 to 0.4 cc of carbon tetrachloride per kg of body weight was given to a piglet
2) Only a part of the whole parasitic worms was reomved when 8 to 10cc of 5 per cent copper sulfate solution and 0.5 to 0.7g of thymol solution in alcohol were administered.
3) Very little anthelmintic effect was displayed by either of the following agents: 10cc of concentrated tincture of iodine, silver nitrate solution, acetic acid (Japanese Pharmacopoeia), thymol, oil of turpentine, or 10cc of 10 per cent mikezoru, a proprietary disinfectant.
4) When 5 to 7cc of 5 to 10 per cent copper sulfate solution and 1.5 to 1. 7cc of oil of chenopodium were mixed and introduced, a considerable effect was recognized, although a small number of worms still remained unremoved.
5) Almost the same effect as shown in paragraph 4 was obtained when 5 to 8cc of 10 per cent copper sulfate solution and 10 to 20cc of toluol were administered.
6) The ratio of male to female was 1 to 1.1 among 9, 109 whipworms collected by medication or dissection on piglets.

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An allergic type of food poisoning broke out in some district of Kagawa Prefecture, Shikoku Island, in November, 1955. The incriminated food was fish broiled with sauce, which had been prepared from a species of fish called karasu in Japanese. The previous report dealt with the results of investigations in which a large quantity of histamine (12 mg per gram of fish broiled with sauce) had been detected from the incriminated food, the symptoms manifested by the patients involved, and the histamine-producing ability of the Morganella organisms isolated from the incriminated food. After that, experiments were performed on the effect of the histamine produced by the isolated Morganella organisms upon guinea pigs, especially changes in the differential blood cell count and the actual count of circulating eosinophils in them. The results obtained from these experiments are summarized as follows.
1. When injected intraperitoneally with 3 cc of either histamine, the filtrate of the isolated strain through Seitz filter, or a mixture of histamine and “diphenhydramine hydrochloride, ” guinea pigs showed a sudden decrease in lymphocytes and a sudden increase in neutrophils in differential blood cell counts and a remarkable decrease in actual counts of circulating eosinophils. When the mixture of histamine and “diphenhydramine hydrochloride” was injected, the decrease in the actual counts of eosinophils was relatively a little slow.
2. In guinea pigs injected with “diphenhydramine hydrochloride” solution, a decrease in lymphocytes and an increase in neutrophils in number were observed as in those injected with histamine, the Seitz filtrate of the isolated strain, or the mixture of histamine and “diphenhydramine hydrochloride.” The trend of such decrease or increase, however, was slow and the recovery of these cells to their normal numbers was rather rapid. No conspicuous changes were recognized in the actual count of eosinophils.
3. In guinea pigs injected with a culture medium to which was added histidine, changes were hardly noticed in lymphocyte and neutrophil leukocyte counts and actual counts of eosinophils.
4. In 5 cases examined, there were no distinct changes in the number of monocytes and no definite trend in the fluctuation of white blood cell counts in which some increase or decrease had been observed.

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These studies were performed to obtain any basic data on patho-physiological investigation of serum protein in dairy cattle. Among dairy cattle kept in the suburbs of sapporo, Hokkaido, and regarded as healthy from clinical examination, 154 cows of the pure or hybrid Holstein breed and 10 Holstein bulls were selected for these purposes. The normal value of the serum protein level was determined in them by using a refracto-proteinometer of Hitachi model and paper electrophoresis. As a result, the following data were obtained.
Serum protein level in cows-total protein level 6.81±0.56 gidl, albumin: 41.7±5.8%, globulin: 58.3±5.3%, α-globulin: 13.9±2.5%, β-globulin: 10.7±1.9%, γ-globulin: 33.9±6.2%, and albumin /globulin: 0.71±0.18.
Serum protein level in buts-total protein level: 7.37g/di, albumin: 36.9±63.57%, globulin 63.1±63.57%, α-globulin: 11.2±12.11%, β-globulin: 13.3±4.11%, γ-globulin: 38.6±42.37%, and albumin/globulin: 0.58±0.043.
Discussion was also made by comparing these data with those described in other papers published.

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