An 11-year-old male dachshund was found to have a pink cauliflower-like tumor on the gingival mucosa of the lower jaw at the right second and third premolar teeth. No adjacent lymph nodes were swollen. The tumor recurred in spite of repeated surgical removal. Biopsy revealed that no epithelium was cornified, that few mitotic cells were present, and that keratinization took place in many indivitual tumor cells, which proliferated to infiltrate into the submucosa. As a result, this case was diagnosed as oral florid papillomatosis. It responded satisfactorily to treatment with bleomycin.
A 3-year-old tortoise-shell female cat was laparotomized on account of pot-belly and celialgia. An excessively large fetus was found free in the peritoneal cavity. The uterus was enlarged with no laceration. The placenta was attached to the omentum majus.
Infectious bovine rhinotracheitis (IBR) occurred on three farms adjacent to one another. Conjunctival congestion, lecrimation, palpebral sebum, and rhinorrhea were observed, but no respiratory symptoms appeared at all. On one farm raising 95 cattle IBR attacked 83 cattle in about 10 days. IBR virus was isolated from ocular and nasal swabs from 11 of 19 cattle clinically infected. At autopsy on cattle showing a high antibody titer, IBR virus was isolated from tonsils and lymph nodes, suggesting that the virus might be discharged from infected cattle for a long time. M. bovis was also isolated from four cattle with severe ophthalmic symptoms which had no abnormality in the cornea.
Monensin is a biologically active compound produced by Streptomyces cinnamonensis. Chicks were administered continually with monensin at a level of 240 ppm in feed, the highest concentration tested. An almost complete preventive effect was seen against infections with Eimeria tenella, E. acervulina, E. maxima, and E. brunetti, judging from the lesion scores and counts of oocysts reproduced. Sufficient growth rates were obtained from chicks medicated with 120 ppm of monensin in feed. Culture media containing monensin in various concentrations were added to BHK 21 cell cultures, to which E. tenella sporozoites were inoculated. A complete inhibitory effect was demonstrated against the development of organisms at a level of 0.001 ppm (10-9) of the drug added to the culture medium. Effective anticoccidial activity against E. tenella was observed when the drug was administered at 120 ppm for chicks and at 0.001 ppm for BHK 21 cell cultures within 24 hours after inoculation. Monensin was highly effective in early developmental stages of coccidia.
Two canine hearts with persistent left superior vena cava (PLSVC) were found among 22 normal canine hearts collected at the Heart Institute of Japan. They had no communication between the right and left superior vena cava (SVC). Therefore, they had bilateral SVC. LSVC was connected with the right atrium through the coronary sinus, taking the same course as the ligament of Marshall. In one case PLSVC was complicated with ventricular septal defect the other case was free from any associated lesion. On the other hand, PLSVC was found in 51 of 1, 236 human specimens of congenital heart disease. In 46 of the 51 cases, this anomalous vein was connected with the coronary sinus in the same mannet as in the dog. In the remaining five cases, PLSVC entered the left atrium (LA) directly. No dogs have ever been reported up to the present to have PLSVC entering the LA. This anomalous vein is not clinically significant unless it opens into the LA. Knowledge of its appearance will aid an angiocadiographic interpretation.