Prostaglandin F2α (PGF) was injected intramuscularly into 76 cows suffering from uterine diseases with persistent corpus luteum. The results obtained are as follows. 1. Fetal death (mummification and maceration of the fetus) occurred in 25 of 27 cows within 3 days after treatment with 10-30mg of PGF. 2. Pyometra was treated successfully in four of 10 cows. 3. Estrus recurred and conception was caused by A. I. in 3 cows with myxometra injected with 12mg of PGF. 4. Retained lochia was evacuated in 33 cows 2-7 days after treatment. 5. Postendometritis with persistent corpus luteum was treated successfully in 5 cows given 12mg of PGF. 6. Progesterone levels in the plasma were below 1 ng/ml in all animals 1 day after PGF injection, though they were 3-7ng/ml at the time of PGF treatment. These results suggest that PGF may be effective against luteolysis with symptoms.
Eight strains of Pseudomonas aeruginosa were isolated from the fresh feces of 259 horses. Serologically, they consisted of 1 strain each of types A, I, and K, 2 strains of type G, and 3 strains of type B. Elastase, protease, and exotoxin were produced by 4 strains, protease and exotoxin by 3 strains, and only exotoxin was by 1 strain. All the strains were highly sensitive to CL, GM, PB, and DKB, many of them also sensitive to PcS and TC, and few to CER, KM, and PC.
A survey on antibiotic resistance and R plasmids was carried out in 9, 696 Escherichiacoli strains isolated from swine and their environment. Resistant strains and R plasmids were isolated at a high frequency from swine, flies and drainage from pig breeding houses. Of these strains, 95.0% was resistant and 34.7% of them had R plasmids was isolated from mother sows; 98.1% was resistant and 27.4% of them had R plasmids isolated from growing pigs; 93.6% was resistant and 30.4% of them had R plasmids isolated from newborn piglets. CL- or NA-resistant strains were not detected from any material.
A 22-day-old calf was found to have congenital fistula between the right coronary artery and the right atrium. The heart was severely hypertrophic. The ductus arteriosus and foramen ovale were widely patent. The right coronary artery was markedly dilated in the coronary groove to be 1.8cm in diameter. It was also enlarged further in the atrium, forming a saccular dilatation 2 by 3cm in size. This dilatation included six fistulae 0.7 to 3.5mm in caliber. As a result of hypertension of both atria due to a large shunt, general congestion followed by pulmonary hemorrhage was considered to be a cause of debility and death of the calf.