Clinical symptoms common to five representative canine cases of graft disease induced by homologous. partial, whole-layer keratoplasty were vascularization of the original corneal ring appearing within 7 days after operation, split of wound in the host-graft junction within 20 days, and white turbidity of the whole graft within a month.
Characteristic histological changes were the appearance of a distinct retrocorneal membrane in 4 cases and the formation of a Descemet's membrane-like structure in the other case. Adhesion of the iris to i he retrocorneal membrane was observed in 3 cases. It seemed to have exerted great influence upon the pathological changes of the graft.

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A total of 72 abscess lesions were found in 37 of 194 pigs examined. Of them, 59 were clinically detectable on limbs, body surface, and tail, suggesting the invasion of causal agents through an injury or scratch on the body surface. Mixed cultures at a few bacterial species and a limited number of pure cultures were obtained. The majority of the isolates were identified as corynebacterium pyogenes (63.8%) and Corynebacterium pseudopyogenes (33.3%). A few species of emidentified Gram-negative bacilli and anaerobic bacilli also ap peared in 30-40% of the mixed cultures. The appearace of streptococci and staphylococcus aureus was rather limited. C. pyogenes was isolated from 25 of the 37 pigs (66%) bearing abscess.
The gel diffasion precipitation test (GDPT) of Takeuchi et al. employing the protease of C. pyogenes as antigen was found to he a reliable serological test for the diagnosis of C. pyogenes infection in pigs. A modified GDPT enploying two pieces of filter paper soaked with test blood and antigen, respectively, was found to be a practical method which presented almost the same efficacy as the original method.

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Toxoplasmosis broke out collectively on a breeding swine farm. There was a relationship between the stage of rearing of swine and the time of clinical manifestation or morbidity of the disease. Pigs weighing 45-120 kg showed a morbidity of 98% 1-4 days after the outbreak, pigs weighing 10-40kg 59% 4-5 days, adult pigs 57% 5-8 days, and suckling piglets 17% 15 days. On the whole farm 74 of 137 head (54%) showed clinical manifestations.
Infected animals were detected by taking body temperature and treated immediately with sulfamonomethoxine. As a result, they recovered 3-9 days later. Ten of eleven of them were negative for protozoa, suggesting the effect of early treatment with the agent.
Hemagglutination antibody against Toxoplasma increased remarkably in titer in all the swine, both clinically infected and not clinically infected, on the farm, indicating that no animals were exempt from infection. An antibody survey revealed that all the young born 1-2 months after the outbreak had been infected, but that those born 6-7 months after the outbreak were free from infection. The present outbreak may have been caused by oral infection with Toxoplasma oocysts.

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