Twenty-two dogs (3 males and 19 females) with transmissible venereal sarcoma were observed hematologically and histologically. Grossly, the tumor was of “diffuse type” in 10 cases and of “localized typet” in 12 cases. That type was shown in quite young dogs and this type in quite old dogs. The tumor occurred to the external genitalia of both sexes and varied in size from 2×2×2cm to 15×17×6cm. No metastasis was observed. The diffuse type exhibited an increase in leukocytes and neutrophils.
Histological examination revealed that the tumor was canine transmissible venereal sarcoma. The mean rate of mitosis in tumor cells of diffuse and localized type was 0.375% and 0.738%, respectively. In the diffuse type, tumor cells showed variability in size, diffuse arrangement, and necrosis. Remarkable features were an increase in stroma, polynucleocyte infiltration on the surface of the tumor mass, and an hemorrhagic tendency and cellular infiltration in connective tissue surrounding the tumor. In the localized type, an active vascular reproduction. in connective tissue surroundingthe tumor was remarkable.

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In July, 1978, the trematode Isopararchis hypselobagri was found in the muscle of the freshwater fishes, Zacco temminckii and Z. platypus. Both mature and immature forms of the fluke were parasitic to the former, but only mature ones to the latter. The morphology of the fluke was described.

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Fasciola metacercariae were allowed to encyst on rice straws and polyethylene sheets left in the field in Sendai in August. They retained their infective capacity when examined in November and September, respectively. The same experiment was performed in December, and the metacercariae were found to maintain their infective power until April and February of the following year, respectively. In both experiments mice were used to examine infective power of the fluke every month.

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Extraction with a water bath at 100°C for 10 minutes was sufficient for the determination of NO₂-N and NO₃-N contained in feed of vegetable origin. Alumina cream was quite efficient for the decoloration of the extract from feed. In cattle which died from injection with nitrite, the NO₂-N and NO₃-N levels of organs were 77-170 and 313-457 μg/g of antemortem weight and those of blood plasma 550 and 10, 200 μg/dl, respectively. Blood methemoglobin was 87% at the time of death.

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In a 12-year-old mongrel male dog the diagnosis of reticulosarcoma was made clinically. At autopsy, there was generalized malignant lymphoma. Additionally, there was a firm cholecystic tumor 6×6cm in size obliterating the cavity of the gallbladder. Histologically, the tumor was cystopapillary adenocarcinoma. Metastasis was present in the lungs and their hilus lymph nodes where the reticulosarcome was located. No gallstones were present.
Spontaneous cholecystic carcinoma is extremely rare in dogs, and very seldom to appear with malignant lymphoma.

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