A goat showed loss of appetite and astasia, and died at a goat-breeding farm in Okinawa Prefecture, Japan. The mesenteric and hepatic lymph nodes were enlarged. Histopathologically, granulomatous ileitis with ulcer formation and necrotic granulomatous lymphadenitis of the mesenteric lymph node and colic lymph node were observed. Gram-positive bacteria and Rhodococcus (R.) equi antigens were mainly detected in the macrophages of the lesions by Gram staining and immunohistochemical staining using anti-R. equi. R. equi was isolated from the liver, spleen, lungs, intestinal tract and mesenteric lymph nodes. All R. equi were found to be avirulent by plasmid profiles and PCR. The present case was finally diagnosed as R. equi infection. This is the first case of R. equi infection in goats in Japan.
Feline breed predisposition for ureterolithiasis was determined by calculating the odds ratios in 64 cats that were diagnosed with ureteral stones between April 2007 and March 2014 at Azabu University Veterinary Teaching Hospital. Mixed breeds were most frequently presented to the hospital, but they had significantly low odds ratios for ureterolithiasis, whereas purebred cats had higher odds ratios. Specifically, the odds ratios were significantly high in the Himalayan, American Shorthair and Scottish Fold breeds, indicating that these breeds were more likely predisposed to the disease. Other breeds did not show statistically significant results. These results suggest that breed can be a risk factor for ureterolithiasis in certain purebred cats.
We examined the distribution of Corynebacterium ulcerans in dogs, cats and rats in Osaka city. C. ulcerans was detected in five of 137 cats (3.6 %), but not in the dogs and rats examined. The five cats from which C. ulcerans was isolated showed poor physical condition. The five isolates from the positive cats produced diphtheria toxin and showed biochemically identical, common antibiotic susceptibility patterns, genotypes for pulsed-field gel electrophoresis and ribotyping. These results indicated the possibility that genetically identical or closely related C. ulcerans is widely distributed among cats in Osaka city.