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Volume 38, Issue 9
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[in Japanese]1985 Volume 38 Issue 9 Pages 559-567
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSDownload PDF (10336K) -
YOSHIMITSU MAEDE, [in Japanese], [in Japanese], [in Japanese]1985 Volume 38 Issue 9 Pages 568-571
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSA cat died as a result of severe hemolytic anemia after oral administration of DL-methionine (3g/day) for 3 weeks to prevent the feline urolithiasis syndrome (FUS). To examine the toxicity of methionine against cats, 3 healthy cats were administered orally with 2g of DL-methionine daily for 20 days. As a result, many erythrocytes containing large Heinz bodies appeared in the peripheral blood of all the cats at 15 days. At 18 days, the concentration of methionine in the plasma and erythrocytes of the cats reached 9-13 mM (control; 29 μM) and 6 mM (control; 39 μM), respectively. The methemoglobin concentration also increased to 8-29%(control; 2%). Polychromatophilic erythrocytes, poikilocytes and neutrophils with cytoplasmic Dohle bodies markedly increased in number in the peripheral blood of all the cats. In addition, some erythrocytes containing basophilic stipplings appeared in the blood.
All the cats showed anorexia, ataxia and cyanosis between 17-20 days. After the end of methionine administration hematocrit value in each cat began to fall in proportion to a decrease of the erythrocytes with Heinz bodies, and it decreased to 20-26% on the 10th day after the last administration. These results clearly indicate that the administration of excessive methionine to cats induces methemoglobinemia and Heinz body formation in erythrocytes, resulting in hemolytic anemia.View full abstractDownload PDF (2556K) -
SHIGERU ICHIJO, [in Japanese], [in Japanese], [in Japanese], [in Japan ...1985 Volume 38 Issue 9 Pages 571-575
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSThe first occurrence of ovine scrapie in Japan was found over a period from 1981 to 1982. Then, the disease was observed in three Suffolk ewes 3 years old on two farms in Hokkaido in 1984. These ewes showed general pruritus and alopecia, and two of them central nervous symptoms, especially ataxia and convulsion, but none anorexia and emaciation.
They were autopsied 4.5 to 6 months after the onset of disease. Histopathologically, vacuolation of nerve cells and slight spongy state of gray matter of the central nervous system were observed in midbrain, pons and medulla oblongata.
The ewes affected had been introduced into these farms in the stage of lambs from a farm in Hokkaido where the first occurrence of ovine scrapie in Japan was reported. They were in the 3rd generation of ewes imported from Canada in 1974.View full abstractDownload PDF (6898K) -
TAKEO SAKAI, [in Japanese], [in Japanese], [in Japanese], [in Japanese ...1985 Volume 38 Issue 9 Pages 576-580
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSStudies were made on responses of insulin and glucagon contents in blood to a rapid or drip injection of 500mlof 50% glucose solution or 1000mlof 25%xylitol solution in 13 healthy mature Holstein-Friesian daily cows.
In 3 cows injected rapidly with the glucose solution, blood glucose and insulin levels began to increase immediately after injection to be 6.9 times (T1/2=30min, k=-2.29%/min) and 5.6 times, respectively, as high as the preinjection-values. In 3 cows receiving drip injection of the glucose solution, they began to increase immediately after injection to be 2.0 and 4.4 times respectively, as high as the preinjection-values.
In 4 cows injected rapidly with the xylitol solution, a peak in blood xylitol concentration appeared immediately after injection (T1/2 =11 min, k =6.35%/min). Blood glucose level was 2.1 times as high as the preinjection-value at 120 min after injection. Blood insulin level at 15 min and glucagon level at 45 min were 16.8 and 3.6 times as high as the preinjection-values, respectively. In 3 cows receiving drip injection of the xylitol solution, blood glucose and insulin levels were 1.3 and 2.3 times, respectively, immediately after injection, while the glucagon value showed little change during the experimental period.View full abstractDownload PDF (668K) -
HIROYUKI MAEDA, [in Japanese], [in Japanese], [in Japanese]1985 Volume 38 Issue 9 Pages 581-586
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSRigor mortis was noticed to develop very early in some pigs slaughtered in a usual slaughterhouse system. An attempt was made to clarify the relationship between the abnormal phenomenon and meat quality.
There were interesting similarities between Subgroup A of pigs showing early rigor mortis and Experimental Group I and between Subgroup C and Experimental Group, II concerning the developing time of rigor mortis, changes in temperature and pH value of the carcass, and meat quality. In this experiment it was possible to produce PSE pork and DFD-like porcine meat.View full abstractDownload PDF (7496K) -
KENICHI SAKURAI, [in Japanese], [in Japanese], [in Japanese], [in Japa ...1985 Volume 38 Issue 9 Pages 587-590
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSOn a daily farm, 7 cows were died suddenly. Autopsy on 3 of them revealed a muddy section of the spleen and the dark red muddy contents of the jejunum. Striking histologically wereedema in the abomasum and the large intestine, and edema and cell infiltration in the small intestine. Bacteriologically, 105-109 organisms of Clostridium perfringens per ml were isolated from the duodenal and jejunal contents of 3 cows. Toxin in the small intestine was proved. The isolated strains were toxigenic and of type A. They were derived from homemade assorted feed, littey in the cowhouse and feces of cows keptin the same barn with the dead cows. These cases were diagnosed as necrotic enteritis by C. Perfringens type A, which was considered to have contaminated an abnormally high protein ration fed.View full abstractDownload PDF (743K) -
KAMEO SHIMURA, SHINGO ITO1985 Volume 38 Issue 9 Pages 590-594
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSTwenty apparently healthy goats were examined for the isolation of Sarcocystis and other coccidia of dogs and cats. Saline suspensions were made from goat muscle for the examination of bradyzoites. Bradyzoite-like organisms were found in 5 goats. Goat muscle were fed to17 cats and 5 dogs. Toxoplasma-like oocysts were shed in the feces of 8 cats (isolates G-1 to G-8). No sporocysts were shed from any cat or dog within 50 days after feeding.
Mice were inoculated orally with oocysts of the 8 isolates. Isolates G-1 and G-6 were highlypathogenic for mice. The other 6 isolates showed mild pathogenicity for mice. All the isolates, except G-8, showed infectivity to mice and sero-positive for Toxoplasmagondii to be identified as T. gondii. One mouse died from among those fed 105 oocysts of isolate G-8. No cysts were found in the brain of any mouse fed 104 oocysts and surviving. No antibody against Toxoplasma was observed in the serum of any surviving mouse.
Two kids fed 106 oocysts of isolate G-5 showed fever, diarrhea and cough, suffering from parasitemia. One of then died 11 days and the other was killed 59 days after inoculation. Toxoplasma was isolated from all the organs examined in both kids.View full abstractDownload PDF (870K) -
KEIRO YAMAGUCHI, [in Japanese], [in Japanese]1985 Volume 38 Issue 9 Pages 594-597
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSA half-bred mare 13 years old showed the nephrosis syndrome, including severe proteinuria, hypoproteinemia with hypoalbuminemia and hyperalphaglobulinemia, and marked edema of long continuance. It was autopsied after clinical investigation for 568 days. Histopathologicalexamination revealed chronic membraneous glomerulonephritis with marked thickening of glomerular capillary walls and fibrous proliferation of interstitial tissue. No incidental causes were known for the renal changes.View full abstractDownload PDF (5390K) -
[in Japanese]1985 Volume 38 Issue 9 Pages 598-601
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSDownload PDF (649K) -
[in Japanese], [in Japanese]1985 Volume 38 Issue 9 Pages 602-604
Published: September 20, 1985
Released on J-STAGE: June 17, 2011
JOURNAL FREE ACCESSDownload PDF (710K)
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