Giardia trophozoites were detected in fecal samples from a pet dog (4 years old) with diarrhea. After treatment with metronidazole, the dog recovered from illness and
Giardia was not found in its fecal samples. But detailed examination of the feces revealed
Cryptosporidium oocysts too. Consequently this case was diagnosed as a mixed infection of both
Cryptosporidium and
Giardia. Even after treatment with metronidazole,
Cryptosporidiumoocysts persisted in the fecal samples. This suggests that metronidazole has no anti-cryptosporidial effects. The
Cryptosporidium isolate from this dog was identified as C. canis, specific to dogs, by PCR-RFLP analysis. This is the second report of
Cryptosporidium infection in a pet dog and the first case of mixed infection of
Cryptosporidium and
Giardia in Japan.
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