日本耳鼻咽喉科学会会報
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
64 巻, 5 号
選択された号の論文の9件中1~9を表示しています
  • 第1編 内耳液の総蛋白量測定に関する研究 第2編 内耳液の蛋白質分劃測定に関する研究 第3編 実験的伝音系障害時の内耳液蛋白質に関する研究 第4編 実験的感音系障害時の内耳液蛋白質に関する研究
    伊藤 明和
    1961 年 64 巻 5 号 p. 923-963
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    The author developed a new ultra micro method of protein determination for labyrinthine fluid, and labyrinthine fluid of guinea pigs and rabbits under various conditions was analysed and following results were obtained.
    1) The author developed a new ultra micro method of protein determination applying the principle of crystal pattern of drop. The principle of the method was discussed and by using this method, it was found that total protein level of the perilymph was higher than that of the endolymph or the spinal fluid, and lower than tnat of the serum.
    2) Applying the crystal pattern of drop and ultrafiltration under negative pressure, two new effective methods to concentrate ultra micro samples were developed. By these methods, the paper electrophoresis of protein in labyrinthine fluid was performed.
    3) In experimental otitis media and tubal stenosis, changes in protein level of perilymph was observed.
    4) Changes in protein level of labyrinthine fluid caused by sound stimulation, egg white allergy Reilly's phenomenon, liver and kidney disturbances were closely observed.
  • 第1篇 口蓋扁桃の A.ph 反応
    小松 宏休
    1961 年 64 巻 5 号 p. 964-979
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    The alkaline phosphatase in the palatine tonsil were examined and following results obtained.
    1) The alkaline phosphatase in the tonsil tissue was studied histochemically and biochmically, and its activity was found.
    2) As the distributional comparison of alkaline phosphatase in the tonsil tissue of man, dog and rabbit are similar to each other, they have no differences to kind of animals.
    3) The typical phosphatase reaction in the tonsil tissue was actively indicated to the circular dark layer and semi-circular dark zone surrounding the lymph folicles, being separated the stroma from the folicles by staining. On the other hand, the germinal center of the folicle was generally negativ to the same reaction.
    4) The reaction changes in positivity were recognized in the circular dark layer and semi-circular dark zone. The semi-circular dark zone of the folicles attached to the criptical epithelium and lymphatic masses which are infiltrated in the stroma under epithelium, was often decreased or negative.
    5) From the biochemical observation, the tonsils in the period of physiologic tonsilar hypertrophy were higher in the activity of alkaline phosphatase. It was higher in the school ages than adolescent and adult ages. These phenomenon were significant difference, and have been estimated that the acceleration of the tonsil function was higher than other periods.
    6) In the expermental tonsilitis of the rabbit, the alkaline phosphatase the activity decreased slightly at early period of the inflammation, and at the peaks of inflammation and also at the period of formation of necrosis, its activity was almost negative or obviously decreased. Thereafter, in the period of three or four weeks, the activity became normal, while during this period the infiltrating leucocytes in the inflammed tissue was shown distinct reaction.
    7) From these above mentioned results, the author discussed the relation of the theories of morphological changes of the folicles (Neo, Ueda, Nakagawa) and a hypothesis of tonsil structure and its function (Schwarz).
  • 嗅裂炎に対する私見
    北嶋 俊之
    1961 年 64 巻 5 号 p. 980-989
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    Sulcus olfactorius nasi has a great significance as osmatic locus, but great deal of its specific anatomy, structural state and also of morphological abnormalities remain still unknown.
    From autopsied 47 cases, ranging from the new born to the age of 74 years old, the nasal septum, the upper and the middle meatus on both sides and the ethmoid together with the ethmoidal canopy and the lamina orbitalis were taken out as a whole entity, preserving the structural relation of each other; and the specimens of the 47 cases, that is, 94 materials for both sides (9 cases for 0-4 years old, and 38 cases for over 17 years old) were prepared for continuous serial section of the frontal occiput for histopathological examination. The obtained result is as follows:
    1) Morphology of sulcus olfactorius is very complicated, and there are some observed with stricture, closure and adhesion. The absolute number of adhesion is relatively of low rate.
    2) When delicate differential diagnosis between the closure and the stricture is required, artifact in the process of preparation of the specimens should be taken into consideration.
    3) Any findings transgoing from closure to adhesion are hardly found. In such area as sulcus olfactorius with narrow space and exposed to the chance of infection, the possibility of the closure proceding to the adhesion due to inflammatory change is recognized. In other words, both clinically and histologically inflammation of sulcus olfactorius is to be regarded to exist.
    4) Among the specimens of the new born, the mucous membrances of the middle meatus and the nasal septum are sometimes observed to become adhesive and the sulcus closed. This is considered as congenital anomaly of sulcus formation.
    5) Therefore, the adhesion of sulcus olfactorius among the adult cases are not always of inflamatory change, and it is now revealed that the etiology of the change exists in.
    i. congenital malformation of sulcus olfactorius originated from the embryonic stage
    ii. acquired morphological anomaly of sulcus olfactorius plus inflammation due to the overgrowth of ethmoidal cells.
    It is, however, very difficult to presume its etiology from the finding of organizing adhesion.
    6) Clinical significance of the abnormality whether it is of congenital malformation of acquired inflammation or acquired inflammatory adhesion of sulcus olfactorius is great and should not be neglected.
  • 石丸 幹夫
    1961 年 64 巻 5 号 p. 990-995
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    Staphylococci collected in our department were examined for the sensitivity against Penicillin, Streptomycin, Sulfisoxazole, Sulfisomidin, Kanamycin, Oxytetracycline, Chloromycetin, Gramicidin and Iversal.
    The results obtained were as follows:
    1. The organisums were obtained from nasal vestibulum, pharynx and finger of patients. Fifty-three strains were coagulase-psitive and 79 strains were coagulase-negative. many of these strains were found to be resistant against Penicillin, Sulfisoxazole and Sulfisomidin.
    2. The Staphylococci collected from nose and pharyx were seemed to be less sensitive to the drugs than those from other parts of body.
    3. More resistant variants were found among the in-patients than among the out-patients.
  • 後藤 敏郎, 熊谷 静真
    1961 年 64 巻 5 号 p. 996-999
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    Carcinoma of the sphenoid sinus is rare, and even tumors found in the sphenoid sinus are mostly those tumors invading from the epipharynx or the nasal sinuses. Primary carcinoma case of this sinus has not been reported in the literature.
    In this paper we present a case of primary cancer of the sphenoid sinus. The patient was a 53-year-old male, whose main complaints were headache, amaurosis, exophthalmos and motor disturbance or the left eye without any nasal symptoms. A small polypoid tumor was found in the olfactory fissure on anterior rhinoscopy and not on posterior rhinoscopy.
    After dissection of the maxilla it was revealed that this tumor has originated and extended from the lateral wall of the sphenoid sinus which was destructed exposing the overlying dura mater. The sinus cavity was filled with papillomatons tumor, but the median wall was covered by thin and flat layer-which was later proved as proliferated squamous cell epithelium, and the rest was covered by the ciliated epithelium.
    The ethmoid ahd maxillary sinuses seemed intact and infiltration of the tumor was not confirmed histologically in their mucous membrane.
    The authors believed that this case could be the first case of primary cancer of the sphenoid sinus ever reported in the medical literature.
  • 向笠 朝彦
    1961 年 64 巻 5 号 p. 1000-1003
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    The patient was refered to our clinic becaus of disturbance of internal earfunction.
    For the past six months he had had the attack of Vertigo, ataxia, vomiting and headache. Syncope was accompanied at the first attack.
    On examination, hearing was proved to be within normal limit and vestibular function test also revealed no significant change. The vertigo of the patient was not rotatory type but was the result of instability of his posture due to undetermined cause. Serologytest was positive for syphilis. While examination of cerebrospinal fluid revealed high pressure and pleocytosis, but no xanthochromia was noted.
    On angiograms, there was found subdural hematoma in the fronto-parietal region.
    The signs aud symptoms were considered due to meningial irritation.
  • 吉江 親正
    1961 年 64 巻 5 号 p. 1004-1010
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    One hundred and sixty-two strains of micrococci which were obtained from the exudate in the middle ear of acute or chronic otitis media, were classified after Hucker and Hall's method, in which 112 strains were pathogenic and so staius were non-pathogenic. Pathogenicity of each strain was further studied by animal inoculation and other methods and it was found that 106 strains were pathogenic and 56 strains were non-pathogenic. Although there was slight diocrepancy in the results of the clas sification, Hucker and Hall's methods was thought to be satisfactory for otological bractice, becance of it's simplicity.
    In the acute cases, 3 out of 12 cases or 25% and in the chronicases, 13 out 38 or 38% were resistant to penicillin. Also in the acute cases, 3 out of 12 or 25% and 10 out of 38 cases or 38% were resistant to sulfathiazol.
    In acute otitismedia, the incidence of the demonstration of micrococci was high among the cases under 1 year of age, and it was very low among the cases over 5 years of age. In chronic otitis media, the incidence was high among the cases between the age of 5 and 25.
    Prognosis of the acute otitis media dueto micrococoi was generally favorable although in 7 out of 31 cases without mixed infection, convalescence was prolonged and in 2 cases, the disease was followed by chronic otitis media. In the cases with mixed infection, chromic otitis media followed in 3 out of 12 cases. Micrococci, especially micrococcus pyogenes appeared to have atendency to aguive drug-fastness easily.
  • 後藤 敏郎
    1961 年 64 巻 5 号 p. 1011-1016
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    The author emphasized his opinion in the Japanese Congress of oto-rhino-laryngology in 1960 that the mastoidcells should not be excentrated in tympanoplasty for simple chronic otitis media. As for the reason of his opinion he had stated that reaction in the middle ear are different in three different parts, namely the tympanum, the ossicles and the mastoid cells.
    The epithelium of the mastoid cells is single cuboidal, but in the well developed mastoid it reveals flat cells which resemble endothelial cells. The author could demonstrate phagacytosis of the epithelial cells of the mastoid cells in a case of chronic otitis media. This phenomenon in the mastoid cells epithelium is not so striking, because phagocytosis of the mastoid epithelial cells was found already by Y. Kurita, the author's co-operator, in exprimental otitis media in young pigs.
    On the other hand, there was able to recognize strong regenerating tendency in the epithelium of the mastoid cells, judging from his view point of pneumatization theory.
    In clinical cases the histologic findings of the epithelium of the mastoid cells in chronic otitis convinced us that histological changes in the mucosa are a progressive and reparative process, i. e. healing process, of inflammation. The author believes that this healing process of the mastoid cells in chronic otitis migh the accelerated by use of antibiotics.
    In most cases, otorrhea in acute exacervation of chronic otitis media might be originated from the tympanum or attic and not from the mastoid, because we observed in these cases that the aditus was obstructed by granulation tissue around the ossicles. It means that the mastoid cavity was isolated from the tympanum.
    Difficulty of epithelization of the mastoid cavity after tympanoplasty has been an annoying problem for clinical otologists. The postoperative epithelization of the mastoid cavity is difficut in the welldeveloped mastoid cells, according to our clinical experience. Even if the epithelization was once completed after the operation several weeks or months later the epithelium usually disappears again and will develope granulation tissue.
    In the discussion on this problem the author has described mechanism of the process and he pointed out the regeneration and cyst formation of the epithelial cells of the mastoid under the transplanted epidermis. This regeneration of the epithelial cells might cause the atrophy and ablation of the transplanted epidermis.
    Concerning prevention of this phenomenon he has recommended several methods. Among these the most effective method is to leave the retroauricular wound open after the completed excentration of the mastoid contents.
    The author would like to emphasize that the mastoid cells should not be excentrated in tympanoplasty in order to avoid this annoying phenomenon.
  • 柳野 権次郎, 坂本 芳夫
    1961 年 64 巻 5 号 p. 1017-1019
    発行日: 1961/05/20
    公開日: 2008/12/16
    ジャーナル フリー
    A case of maxillary sinus syphilis in a 63-year-old woman her chief complaint was recurrent nasal repoated. Maxillary cancer was suspected, but remarkably thickend mucous membrane bleding was was found in the fontanelle area of the sinus at the fime of the exploration. Biopsy from the mucous membrane revealed syphilitic change. The authors have carried out a statistical survey of syphilis of the nasal sinus and collected five cases from the Japanese literatures and five cases from the foreign literatures which have been reported in the past 10 years.
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