日本耳鼻咽喉科学会会報
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
86 巻, 12 号
選択された号の論文の7件中1~7を表示しています
  • 原田 克己, 河村 正三, 市川 銀一郎, 芳川 洋, 福田 正弘
    1983 年 86 巻 12 号 p. 1447-1454
    発行日: 1983/12/20
    公開日: 2008/03/19
    ジャーナル フリー
    40Hz ERP reported by Galambos et al, were recorded on 14 adults and 7 infants with normal hearing, on 2 patients with conductive hearing loss and 4 patients with sensori-neural hearing loss.
    The results were as follows. 1. The wave form of 40Hz ERP was similar to 40Hz sine waves and the prominent peak in the power spectrum was observed at 40Hz. 2. The amplitude of 40Hz ERP increased as the stimulus intensity was increased. 3. 40Hz ERP was obtained for the tone bursts of 500Hz, 1000Hz, 2000Hz and 4000Hz. However, the amplitude of the response decreased for the stimuli in the high frequency range. 4. The response thresholds were 0-30dB in adults and 5-40dB in infants. 5. The large response of 5μV was recorded on 2 out of 27 cases. This seems to be a myogenic response. 6. The response threshold curves both in patients with conductive hearing loss and sensorineural hearing loss, were parallel to their audiograms.
  • 石田 稔, 荻野 仁, 松永 亨, 堀 哲二, 林 治博
    1983 年 86 巻 12 号 p. 1455-1460
    発行日: 1983/12/20
    公開日: 2008/03/19
    ジャーナル フリー
    Investigation was made in 21 cases with chronic sinusitis where bacteria could be detected in the retention fluid in paranasal sinuses and mucous membrane. The results obtained are summarized as follows: 1. Bacteria were detected at a higher rate in the mucous membrane than in the retention fluid in paranasal sinuses. In 62% of the samples from the retention fluid, bacteria were not detected. 2. Anaerobic bacteria were mostly observed in the retention fluid, while aerobes were dominant in the mucous membrane. 3. In 7 out of 21 cases were detected bacteria in both samples from the retention fluid and mucous membrane, 6 out of them having the same strain in both. 4. The observation that the bacteria of chronic sinusitis were detected at a greater rate in the mucous membrane may be explained that inflammation developed primarily in the mucous membrane and therefore the retention fluid, which was a resultant residue of secretion and bacteria, contained bacteria at a low rate.
  • 深谷 卓, 奥野 妙子, 小松崎 篤
    1983 年 86 巻 12 号 p. 1461-1464
    発行日: 1983/12/20
    公開日: 2008/03/19
    ジャーナル フリー
    The origin of early acoustic nuromas was identified near the Bill's bar, during the translabyrinthine surgery. Findings were evaluated in regard to caloric testings in eight patients (4 ear tumors, 4 small tumors which extended less than 10mm into the posterior cranial fossa).
    In five cases, the tumor originated from the inferior vestibular nerve and in two cases from the superior vestibular nerve. The origin of the tumor could not be identified in one case.
    Two-of-five cases with the tumor from the inferior vestibular nerve showed almost normal caloric responses, and the other six cases showed reduced caloric responses. No relation was obtained between the tumor size and caloric responses. These findings suggest that in early acoustic neuromas caloric responses do not relate with the tumor size but with its origin.
  • 尾股 丈夫, 小針 啓生, 大内 仁, WALTER SCHATZLE
    1983 年 86 巻 12 号 p. 1465-1471
    発行日: 1983/12/20
    公開日: 2008/03/19
    ジャーナル フリー
    The afferent and efferent nerve endings of the outer hair cells of the rabbit after acoustic exposure were investigated with electron microscope. After acoustic stimulation the afferent nerve endings of normal range were 57%. And in the other nerve endings, the small vesicles decreased in number and mitochondriae were dilated.
    After acoustic stimulation the efferent nerve endings of normal range were 64%. And in the other nerve endings, the small vesicles decreased in number and mitochondriae were dilated or distributed in the whole nerve endings. Synaptic vesicles agglomerated at some sites fronting the synaptic cleft. These agglomerations of synaptic vesicles were observed in 67% of the nerve endings in the control group, but in only 26% of the nerve endings after acoustic exposure.
  • 2症例の経験
    熊川 孝三, 松本 和彦, 北原 伸郎, 船井 洋光, 船坂 宗太郎, 矢野 純, 牛嶋 達次郎
    1983 年 86 巻 12 号 p. 1472-1477
    発行日: 1983/12/20
    公開日: 2008/03/19
    ジャーナル フリー
    A large bony defect of the frontal sinus gives rise to a local retraction of the forehead unless the plastic reconstruction is performed. The pelvic bone, which is mainly used for this purpose as an autograft, has the following problems, that is, a new surgical intervention is necessary, and a large bone fragment is hard to get in the case with a wide frontal defect, and the cosmetic reconstruction is not always satisfactory. On the other hand, use of exogenous materials has not been popular for this kind of plasty because of their poor biocompatibility.
    Apatite ceramics have been attracted a special attention as a prosthetic inlay on account of its good biostability and biocompatibility. This led us to use apatite ceramics for the reconstruction of the bony defect of the frontal sinus.
    2 cases of clinical experience are reported. A porous apatite plate with 4mm. in thickness and 55% of pore rate was used. This plate has a curvature to fit to the forehead. After trimming of the apatite plate, it was inserted into the bony defect and periosteum was then sutured to cover it. Follow-up periods on these cases are 7 months and 4 months respectively, and patients are in the uneventful condition without infection or extrusion. This material seemed to be useful in the reconstruction of the bony defect of the frontal sinus.
    We propose that apatite seramics can be applied not only to the frontal sinus but to many other reconstructive surgeries.
  • 永田 雅英
    1983 年 86 巻 12 号 p. 1478-1486
    発行日: 1983/12/20
    公開日: 2008/03/19
    ジャーナル フリー
    Ninety four cases with head and neck cancer have been examined by delayed skin reaction to candida extract, streptokinase-streptodornase (SK-SD), OK-432 and phytohemaggulutinin (PHA) at one point of the pretreatment of the cancer patient. Additionary, number of total, T and B lymphocytes in the peripheral blood, alpha-fetoprotein and carcinoembryonic antigen (CEA) were also estimated.
    Relationship between the results obtained and the four following factors; (1) T classification, (2) size of the cancer, (3) immunological data of the patients who have no recurrence more than 3 years after therapy and (4) prognosis was statistically analysed.
    The results indicated following conclusions. 1) There were no significant correlations between lower immune response and volume of the cancer carried by the patient. 2) Lower immune response in the cancer-carried patient has not been recovered by removal of the cancer. 3) Individual lower immune-response is probable of one of the important back ground for the cancer generation. 4) The delayed skin reaction to SK-SD is immunologically the most reliable results to reflect a state of cancer-carried patient including the prognosis. 5) Population of total, T and B lymphocytes in peripheral blood and the titer of alpha-feto-paotein and CEA indicated no significant differences between the groups observed.
  • 大槻 好正, 大谷 巌, 相川 通, 佐藤 洋子, 安斉 友博, 大内 仁, 斉藤 武郎
    1983 年 86 巻 12 号 p. 1487-1496
    発行日: 1983/12/20
    公開日: 2008/03/19
    ジャーナル フリー
    The influence of Fosfomycin (FOM) on inner ear and renal damage due to Dibekacin(DKB) was investigated using Fischer 344 rats as the experimental animals. DKB (100mg/kg/dayor 50mg/kg/day) was administered in single daily either alone or in combination with 500mg/kg/day of FOM for 60 or 120 consecutive days. Four hours after the last injection the animalswere decapitated and the DKB levels of serum, kidney and perilymph were measured by the bioassay method. Using the surface preparation technique the hair cell damage of the inner ear was examined by means of a phase contrast microscope. The renal damage was examined with a light microscope. Renal function parameters, BUN, urinary NAG activity and urinary protein, were measured. DKB levels of the serum and kidneys were also observed after the first and fifth injection of DKB (50mg/kg) alone and in combination with FOM (500mg/kg).
    The results were as follows. 1. The hair cell damage and renal damage including both histological and functional damage due to DKB were reduced by combined administration with FOM. 2. When administered in combination with FOM, the DKB levels of the serum, kidneys and perilymph after 60 or 120 injections were lower than when DKB was administered alone. 3. After the first and fifth injection the serum DKB levels were not significantly different between the two groups but the kidney DKB levels after the fifth injection were lower in the animals receiving FOM, although the accumulation of DKB was observed in both groups.
    It is thought that the protective effect of FOM against DKB induced ototoxicity is related to the concentration of DKB in the kidneys, serum and perilymph. The decrease of the concentration of DKB was attributed to FOM's inhibition of the accumulation of DKB in the kidneys and not to the acceleration of DKB excretion from the kidneys by FOM.
    It is concluded that this combined administration first inhibits the accumulation of DKB in the kidneys and then decreases the serum and perilymph DKB levels, resulting in a subsequent reduction in inner ear damage.
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