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65 巻, 10 号
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新井 泰1962 年 65 巻 10 号 p. 1131-1148
発行日: 1962年
公開日: 2007/06/29
ジャーナル フリーTo study the effects of intense sound stimulation on ear-labyrinth right ear of rabbits were subjected to the acoustic stimuli with the white noise at 130 phon.
Clinical and histopathological observation of the organ were wade and the following results were obtained.
A) Clinical findings
1) Spontaneous nystagmus was seen in many cases, and at first it was seen to be fowards the stimulated side, and afterwards towards the nonstimulated side,
2) Cupulogram was of the parallel-type, and there were directional preponderance to the left (non-stimulated side).
3) Compensative eye-deviations were decreased to about 10°-15° in the lower position of the stimulated side.
4) Head-position nystagmus was maximum in the lower position of the non-stimulated side,
Morever, dilatation of the pupille, deviation of the ey-ball, and disapperance or decrease of the position reflex were found.
From these results it was surmised that saccle was the site which most influenced by intense sound stimulation.
B) Histologieal findings
1) Representative findings at the cochlear labyrinth were degeneration of outer hair cell and removal or disapperane of the corti's organ at the second turn. Localisation of the Changes in the corti's organ was of particular interest.
2) Spiral ganglion cells exhibited a slight degree of atrophy on the V group.
3) Representative findings at the vestibular labyrinth were mainly changes of Saccule: Namely sinking of the saccular membran, atrophy or degeneration of the sensory cell, and exudation substance or bleeding of the endlymphatic cavity of saccule.
Changes in the Utriclar macula and cupula, however, was not seen.抄録全体を表示PDF形式でダウンロード (3933K) -
高原 定幸1962 年 65 巻 10 号 p. 1149-1158
発行日: 1962年
公開日: 2007/06/29
ジャーナル フリーThe reliability of the results of EEG-audiometry was studied on 20 examinees of 2 to 24 years of age. Pure tones of 500cps and 2000cps were used as auditory stimulus. In order to exclude the reader's prejudice and expectancy in the judgement of EEG records, a series of 40 different arrangements of 6 signs were made by using the random number table, half of these 6 signs indicating the auditory stimulation of 3 respective intensities of 20, 50 and 80db and the remaining half the sign of nostimulus. The reader (the present author) operated the tone-interrupter of an audiometer, while an assistant set the intensity dial of the audiometer according to one of the 40 arrangements of the signs without information to the reader. Thus the varied stimuli, interspersed irregularly with no-stimulus phase, was presented at random to the examinees, and the reader had to decide the presence or absence of a response solely on the basis of objective characteristics of the EEG records.
The results obtained were summarized as follows:
1. The ratio of the recognizable responses in the EEG records to the auditory stimuli ranged from 71.8 per cent (500cps at 20db) to 90.0 per cent (2000cps at 50 and 80db), revealing the fact that the ratio of the correct judgement became higher as the intensity of the stimulus increased.
2. The ratio of the correct judgement for nostimulus phase was 76.1 per cent at the initial judgement, while it reached to 83.0 per cent by the re-examination of the records.
3. In general, the ratio of the correct judgement tended to be higher in the adult EEG records than those of children. However, when the auditory stimulation was near the hearing threshold of the examinees, no age difference was found in the ratio.抄録全体を表示PDF形式でダウンロード (2505K) -
南立 純一郎1962 年 65 巻 10 号 p. 1159-1164
発行日: 1962年
公開日: 2007/06/29
ジャーナル フリーFrom four hundred and fifty nine cases of nerve deafness of various degree, cause of deafness and its relationship with the audiogram symmetry were studied.
Symmetrical audiograms was most frequently seen in presbyacusis, streptmycine deafness and so called occupational deafness, and the frequency decreased in order of deafness complicated with general infection, acute acoustic trauma, ménièr's syndrom, brain tumor and lastly, sudden deafness.
Since Langenbeck's Symmetric Gesetz 1936, congenital disposition has been emphasized as a most primary factor determining audiogram symmetry.
From above the order of symmetrical audiogram frequency, however, it has been noticed that when the cause was more intense or the onset was more acute, the changes in symmetrical audiogram became less.
When mechanism of the cause was added, the following conclusion was proposed. Primary factor determining audiogram symmetry was the balance of the effect of the cause on each ear, rather than existence of congenital disposition.抄録全体を表示PDF形式でダウンロード (528K) -
坂田 英治1962 年 65 巻 10 号 p. 1165-1177
発行日: 1962年
公開日: 2007/06/29
ジャーナル フリー12 Normalhörenden and 54 Patienten wurden über den Otolithenreflex klinisch untersucht, darunter bei grösstenteils der Patienten der rein rotierende bzw. horizontal-rotierende Nystagmus zu beobachtet und Vestibularisstörungen vor allem durch periphere Vestibularisläsionen erklärbar sind.
Als Gegenstand des Studiums des Otolithenreflexes wurde die Messung der kompensatorischen Gegenrollung der Augen, besonders die schnelle Phase der vorübergehenden Gegenrollung (sog. rotatorischer Neigungsnystagmus), aufgenommen.
Unsere Untersuchungsergebnisse können wie folgt geordnet werden.
1. Durchschnittswert dieser Messung bei Normalhörenden zeigte 20.0° (rechts) und 21.3° (links).
Das stimmt mit dem Messungswert von Bárány überein.
2. Bei Patienten steht der Messungswert in allen Fällen mit Ausnahme von 3, ausserhalb des normalen Bereiches.
Trotz des normalen Ergebnisses in den kalorischen oder audiometrischen Prüfungen zeigten 12 Fällen bei der Prüfung der Gegenrollung der Augen den abnormen Wert.
Und bei der kalorischen Prüfung zeigten 50% der untersuchten Fällen Kanalparese oder Nystagmusüberwiegen. In der kalorischen Prüfung bzw. der Gegenrollung der Augen stand ein Zweitel der 22 einseitigen Abnormhörenden ausserhalb des normalen Bereiches.
3. Da der rein rotierende oder horizontal-rotievende Nystagmus relativ häufig bei gleichzeitiger Ohrerkrankung beobachtet wird und noch mehr bei obengenannten Fällen Messungswert der Gegenrollung der Augen oft abnorm ist, kommen wir zu der Überzeugung, class die Gegenrollung der Aungen vom Otolithenapparat ausgelöst sei, auch wenn sie kein anderes Ohrsymptom beglitten ist.
Wiederum haben wir geschlossen, class Schalltrauma u. chronische Mittelohrentzündung, Streptomysin-Vergiftung u. Hypotension als einer der Ursachen der Ménièréschén Krankheit bzw. sog. “Lagenystagmus vom gutartigen paroxysmalen Typ” mehr oder weniger in Betracht gezogen werden können, denn Schalltrauma usw. sind in obengenannten Patienten sehr häufig beobachtet.
Wie oben erwähnt können wir durch die Prüfung der kompensatorishen Gegenrollung der Aungen nicht nur Otolithenfunktion, sondern auch die Beteiligung des Otolithenapparates an den rotierenden Nystagmus erforschen.
Deswegen haben wir ferner betont, dass die Uutersuchung der kompensatorischen Gegenrollung der Augen grosse klinische Wichtigkeiten wie die anderen haben müsste.抄録全体を表示PDF形式でダウンロード (1697K) -
Otitis ext. granulosa 及び myringitis granulosa後藤 敏郎, 村島 二郎1962 年 65 巻 10 号 p. 1178-1181
発行日: 1962年
公開日: 2007/06/29
ジャーナル フリーSix cases of granulating otitis externa and two cases of myringitis granulosa were reported. In the literatures of these diseases the repots by Moffett, Clark, Johnston and Punt were found, but they are not common or usual type of external otitis and myringitis. It may be supposed that these diseases might be miss-diagnosed as chronic purulent otitis media with marginal perforation.
In Japan there has been only one report on this subject by S. Fuwa, our co-worker, in 1953, but little attention has been drawn to these diseases.
Bacteriological examination of these diseases could not confirm any causing microorganisms including fungi.
Histological study of granulation tissue revealed subacute nonspecific inflammation.
On pathogenesis of these diseases the a_??_ have the following opinion. Moist condition _??_ external meatus due to variable conditions _??_ cause desquamation of not the superficial laye_??_ the whole layer of the epithelium in the deep_??_ atus or on the tympanic membrane, becaus_??_ epithelium in these area is extremly thin.
Desquamation of the epithelium might _??_ in growth of granulation, which takes a c_??_ course following secondary infection.
As the treatment curretage or cauterization _??_ granulation, with combined use of antibiotion _??_ effective.抄録全体を表示PDF形式でダウンロード (669K) -
高須 照男, 丹羽 脩, 馬場 駿吉, 中野 弘雄, 月山 昌夫, 岡 節郎, 岩田 重信, 近藤 登, 間宮 敦1962 年 65 巻 10 号 p. 1182-1192
発行日: 1962年
公開日: 2007/06/29
ジャーナル フリー111 cases of patients with chronic sinusitis were treated locally with new antibiotics such as Phenoxyethyl penicillin, Dimethoxyphenyl penicillin, Pyrrolidinomethyl tetracycline, Kanamycin and partially with Leucomycin.
The following results were obtained: Marked improvement 42.3%, moderate improvement 29.7%, slight improvement 20.7% and ineffective 7.2%. But, the long term results were lowered to about one-third of the results obtained above.
These effects were rather closely related to the age of patients, course of onset, pathological changing of nasal cavity and sorts of bacteria in middle meatus. Furthermore, there was some difference between the antibiotics employed.
From the comparative investigation of the sensitivity against staphylococcus which was obtained from the secretion of middle meatus the effects show that the selection of antibiotics must be made more carefully.抄録全体を表示PDF形式でダウンロード (1289K) -
本杉 雅英, 佐藤 喜一1962 年 65 巻 10 号 p. 1193-1196
発行日: 1962年
公開日: 2008/07/31
ジャーナル フリーA case of 17 year-old female, which showed the Parkinsonismus localized in her face and side of the neck as the side effect of perphenazine applied to improve the postoperative nausea of radical mastoidectomy was reported.
There is still no report of the side effect of perphenazine applied even by usual dose during long term in ear nose and throat clinic, much less such a small dose within short term (12mg a day, 3 days). The reason why there is no report of the side effect of perphenazine was discussed.
Although the syndrome of side effect was completely reversible, the inhibitory effect on the development of foetus if the derivatives of this drug was administered to pregnant patients in large enough doses as to cause the side effect can be surmised.抄録全体を表示PDF形式でダウンロード (872K)
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