巻号一覧
後続誌
89 巻 (1986)
- 6 号 p. 689-
- 5 号 p. 559-
- 4 号 p. 419-
- 3 号 p. 261-
- 2 号 p. 135-
- 1 号 p. 1-
前身誌
89 巻, 4 号
選択された号の論文の9件中1～9を表示しています
- |<
- <
- 1
- >
- >|
-
特に臨床像について斎藤 久樹, 朴沢 二郎, 盛 庸, 福岡 敬二, 池野 敬一, 田沢 正之1986 年 89 巻 4 号 p. 419-424
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーFor the purpose of early diagnosis of maligant melanoma of nasal cavity and paranasal sinuses, a statistical survey on the initial subjective or objective symptoms was performed for 181 patients reported in Japanese literatures from 1965 to 1983. Twelve cases of them were authors' own patients. The most common initial symptom was unilateral nasal bleeding or obstruction. Colors of the tumor at the patients' first visit to the hospital were black or dark brown in 51.9%, dark or light red in 35.8%, and white or white gray in 12.3%. Abonormal shadow of nasal cavity and paranasal sinuses in X-ray films was observed in 76.9%, and bone destruction in 28.2%. Although 89.7% of the patients did not show metastasis at the first visit, the distant metastasis appeared after treatments and 53.4% of them died for the metastatic tumor. To prevent the metastasis, biopsy presupposing the radical operation is necessary, and adequate multidisciplinary treatment before and after the operation are desirable.抄録全体を表示PDF形式でダウンロード (1521K) -
牧山 清1986 年 89 巻 4 号 p. 425-432
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーIt is well known that histamine is the most important chemical mediator of nasal allergy, and histamine hypersensitivity of the nasal mucosa has been also recognized in the patients with nasal allergy. Therefore, the degradation or inactivation of histamine released from basophilic cells following reaginic antigen-antibody reaction is very important in the patients from a view point of the defence mechanism of the body.
The purpose of this study is to investigate the levels of plasma histaminase of allergic patients both in pollen season and in season without pollen of Japanese cedar. The patients have developed clear symptoms due to allergen challenge during the pollen season.
Higher plasma histaminase activity was revealed in pollen season than that out of season. Furthermore, close relations were recognized among the plasma histaminase activity and nasal symptoms, local findings, eosinophils in nasal secretion, and histamine sensitivity of nasal mucosa during the pollen season.抄録全体を表示PDF形式でダウンロード (560K) -
実験的研究五十嵐 文雄1986 年 89 巻 4 号 p. 433-440
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーThe effect of chronic middle ear inflammation on the development of mastoid air cell system was investigated in piglings, whose tympanic bullae closely resemble the human mastoid air cell system.
Experimental chronic otitis media was produced by the injection of glycerin into the middle ear cleft of piglings aged from 5 days to 5 weeks after birth. The piglings were subsequently decapitated and the temporal bones removed at 50 days, 2 months, 4 months and 6 months after birth, to examine and compare the degree of pneumatization of the tympanic bullae histologically, against that of non-treated control group.
In the non-treated control group free of inflammations, the tympanic bullae were developed as a result of the bone formation by the osteoblasts, and the air cell system was developed widely inside of the cortex due to the bone resorption by osteoclasts. On the other hand, in the tympanic bullae of treated animals, non-specific chronic middle ear inflammation was noted and, although the bone formation by osteoblasts progressed as in normal tympanic bullae, very few osteoclasts were observed. This suggested reduced bone resorption by osteoclasts due to the inflammatory stimulus. Moreover, it was found that later the time of removal of the temporal bone, the larger the proportion of the bone mass occupying the tympanic bullae, and only slight remnants of the air cell system was detectable near the middle ear cleft in glycerin treated 6 months old piglings.
The tympanic bullae and the air cell system of normal piglings were well developed due to the bone formation and the bone resorption inside the cortex, whereas the tympanic bullae of piglings afflicted with chronic otitis media in the early stages of life exhibited retardation of pneumatization arizing from the disturbance of bone resorption by inflammatory stimulus, resulting in thickened residual bone mass with development. Therefore, the development of air cell system was inhibited severely in spite of the normal growth of tympanic bulla itself.
In conclusion, it was thought that affliction with chronic middle ear inflammation in the early stages of life induces the inhibition of pneumatization by hindering the developmental process of the air cell system.抄録全体を表示PDF形式でダウンロード (3363K) -
Wet-SEMによる観察とX線分析竹内 亘1986 年 89 巻 4 号 p. 441-447
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーChemical fixation and dehydration are known to alter ionic components of the specimens, so specimens are desired to be observed and analyzed in their native state. Recently low pressure SEM (Wet-SEM) having been developed, specimen are able to be observed and analyzed without fixation and dehydration. In this study, the soft tumor from the right side maxillary sinus was studied by the Wet-SEM (SW-300, Akashi Seisakusho Ltd.) and fine structures and ionic components were investigated. The tumor removed was cut into two parts ; one for light microscopic study another for Wet-SEM study. For Wet-SEM, samples were fixed with acrolein gas to prevent ionic movement. The specimen were observed and analyzed under 0.3-0.5 Torr and at 25kV. Light microscopic examination showed that the major of the tumor was lined with degenerated epitherial like substances. The inner part of the tumor was not stained with hematoxyline and eosin, and filled with unstained foamy structures. A remarkable peak of iodine, which was not able to be detected by routine specimen preparation methods, was detected from the foamy structures. Judging from the results obtained, the tumor is likely to be derived from the remnants of a contrast medium containing iodine. And it was suggested that the tumor may become endogenous nucleus of the maxillolith.抄録全体を表示PDF形式でダウンロード (2013K) -
河村 裕二, 丘村 煕, 湯本 英二1986 年 89 巻 4 号 p. 448-454
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーThe authors proposed a new method of the multiparametric display of vocal function using a radar chart. The purpose is to visualize the degree and feature of vocal dysfunction in various laryngeal diseases. The parameters analyzed were the fundamental frequency (F0), intensity of the voice, the transglottic air flow rate (F.R.) and AC/DC ratio of the expiratory air flow, which were simultaneously recorded during phonation of the vowel /a/ in the following five different fashions: easy, high-loud, high-soft low-loud and low-soft. The radar chart for easy phonation consists of four axes (F0, Intensity, F.R. and AC/DC ratio) arranged rectangularly, and the scales were determined to give a regular square for normal subjects. The radar charts for high and low pitched voices consist of six axes (F.R. and AC/DC ratio of loud and soft voices respectively, Fα and Intensity), and the scales were determined to give a regular hexagon for normal subjects.
The new display was valuable for investigating the degree and feature of vocal dysfunction and for judging therapeutic effects.抄録全体を表示PDF形式でダウンロード (550K) -
高原 哲夫, 藤谷 哲造, 井上 健造, 納 一功, 服部 浩, 溝尻 源太郎, 押谷 高志1986 年 89 巻 4 号 p. 455-461
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーSixty-one patients with carcinoma of the soft palate and uvula seen at the Kobe University Hospital, from 1966 to 1984, were reviewed. The results obtained from this study were as follows.
(1) The overall 3- and 5-year-survival rate for all patients in all stages was 60.6% and 46.8 %, respectively.
(2) Histologic tumor type and the presence of regional lymph node metastasis appeared to be the most important factors influencing prognosis; the 5-year-survival rate of patients with squamous cell carcinoma (36.5%) was lower than those of the other carcinomas of minor salivary gland origin (90.9%) and the 5-year-survival rate of NO patients (68.4%) was better than that of N+patients (11.4%).
(3) Irradiation was the first choice of treatment for most patients, but residual or recurrent tumors were often observed in both the local area and regional neck lymph node in N+patients. These N+cases should be treated by irradiation with careful evaluation of the radiation effect, and if it proves ineffective, surgical procedure at the early period of radiotherapy is recommended.抄録全体を表示PDF形式でダウンロード (576K) -
中島 格1986 年 89 巻 4 号 p. 462-467
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーImmunohistological presence of the olfactory marker protein (OMP) which is specific to the olfactory neuronal system was studied in the olfactory tissues of rats, Mongolian gerbils and humans. OMP was detected in the perikarya of the olfactory receptor neurons, olfactory vesicles, and processes extending from the olfactory neuroepithelium to the olfactory blub of rats and gerbils. Mucus materials on the surface epithelium also contained OMP. However, supporting cells, basal cells and Bowman's glands did not react to anti-OMP. In the olfactory bulb, olfactory nerve layers and glomerular layers were clearly demonstrated by anti-OMP. Cross reactivity of OMP in human olfactory tissues to anti rat-OMP allowed histologic demonstration of the human olfactory neurons in the neuroepithelium and bulb. Although the human olfactory neuroepithelium was thin and degenerated in greater or lesser degrees, OMP was determined in the perikarya and axonal or dendritic processes of the olfactory receptor neurons.抄録全体を表示PDF形式でダウンロード (2643K) -
西岡 出雄1986 年 89 巻 4 号 p. 468-477
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーPerilymphatic fistula has been believed to cause acute, profound and reversible sensory hearing loss. Over the past five years, exploratory tympanotomy were performed in 27 patients with perilymphatic fistula. In three patients, air bubbles came out of the round window niche in the course of perilymphatic leakage. The perilymphatic fistulae observed in these three patients were attributable to the implosive route. These clinical evidence prompted the experiments using guinea pigs in order to answer the following questions:
1. Can an air bubble enter the perilymphatic space when pressure in the middle ear suddenly rises beyond a certain clitical level?
2. Does an air bubble in the perilymphatic space cause serious but reversible hearing impairment? As a result, experiments showed that:
1. The round window membrane is ruptured when pressure in the middle ear is elevated suddenly even at a level of 400 mmH2O.
2. Air can enter the scala tympani through the rupture.
3. The air bubbles in the perilymphatic space increased the AP (Action Potential) threshold of the auditory nerve immediately. The increase in the threshold was on the order of 10 dB or 50 dB.
4. That change of the AP threshold was reversible after eliminating the air bubbles.
These experimental findings might indicate that the air bubbles disturbed the propagation of traveling waves of the perilymph. Thus the present study strongly supports the assumption that air bubbles in the perilymph may cause profound but reversible hearing loss in patients with perilymphatic fistulae.抄録全体を表示PDF形式でダウンロード (2267K) -
青柳 優1986 年 89 巻 4 号 p. 478-490
発行日: 1986/04/20
公開日: 2008/03/19
ジャーナル フリーThe current status of the application of the fast Fourier transform (FFT) for the auditory evoked response was summarised under for items of importance to the auditory brain stem response (ABR) as follows.
(1) Digital filter: The most common way to use FFT, which facilitates quick isolation of fast and slow components from data of the same ABR wave. In addition, the proper setting of digital filter increase the rate of detection of waves II and IV, the frequencies of which have conventionally been considered to be low.
(2) Power spectrum analysis: It is difficult to obtain clinically significant information from power spectrum in the present situation. However, it seems significant in ABR to isolate and analyze slow, middle (tentative name) and fast components from the Fourier components revolving around each peak of the power spectrum with a three-peak pattern by inverse fast Fourier transform (IFFT).
(3) Cross correlation function: This method is the way to analyze the relationship between two signals from the viewpoint of the phase. Clinical application including application to the diagnosis of multiple sclerosis, application to automatic detection for ABR, etc. are expected in the future.
(4) Phase specteral analysis: The synchrony measure method (Fridman, 1982) is one of the phase spectral analysis made by means of FFT. In this method, phase variance for selected Fourier components are calculated among the averaging groups of 200 sweeps under the same stimulating conditions, in order to determine the presence or absence of response by the degree of the timelocked condition of the Fourier components for stimuli. Its clinical application to automatic evaluation of ABR, etc. is being studied.抄録全体を表示PDF形式でダウンロード (2757K)
- |<
- <
- 1
- >
- >|